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Agilent offers the largest, most modern liquid chromatography (LC) column portfolios for small molecule analysis, with columns suitable for nearly all separation modes and applications.


Whether you are performing conventional or ultra-fast chromatography, separating biomolecules, or analyzing complex compounds, the industry’s highest-performing compounds deliver fast, reproducible results – all engineered with unparalleled quality and reliability.

Catalog No. Product Net Price
AGIL959943-901 ZORBAX RR HILIC Plus, 95Å, 4.6 x 50 mm, 3.5 µm 476 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 50 mm
  • Phase
  • HILIC Plus
  • UNSPSC Code
  • 41115709
  • USP Designation
  • L3
  • Brand
  • ZORBAX
  • Carbon Load
  • 0 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 3.5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 0-8
  • Pore Size
  • 95 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • HILIC Normal Phase SFC
  • Shipping Solvent
  • Acetonitrile/Water
AGIL820950-904 ZORBAX 300Å SCX, 5 µm, 4.6 x 12.5 mm guard cartridge (ZGC), 4/pk. Use with hardware kit 820999-901. A 4-pack of strong cation exchange HPLC guard cartridges that are based on ZORBAX 5 μm silica particles. 237 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 13 mm
  • Phase
  • SCX
  • UNSPSC Code
  • 41115711
  • Brand
  • ZORBAX
  • Guard Column
  • Yes
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 80 °C
  • Part Number Application
  • Peptides Proteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 6 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-7
  • Pore Size
  • 300 Å
  • Pressure Rating
  • 350 bar
  • Separation Mode
  • Ion Exchange (IEX)
  • Shipping Solvent
  • Phosphate Buffer
  • Technique
  • LC
AGIL846952-704 ZORBAX 300Å SCX, 4.6 x 50 mm, 5 µm. A strong cation exchange HPLC column that is based on ZORBAX 5 μm silica particles. 460 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 50 mm
  • Phase
  • SCX
  • UNSPSC Code
  • 41115711
  • Brand
  • ZORBAX
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 80 °C
  • Part Number Application
  • Peptides Proteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-7
  • Pore Size
  • 300 Å
  • Pressure Rating
  • 350 bar
  • Separation Mode
  • Ion Exchange (IEX)
  • Shipping Solvent
  • Phosphate Buffer
  • Technique
  • LC
AGIL860700-304 ZORBAX 300Å SCX, 3.0 x 50 mm, 5 µm. A strong cation exchange HPLC column that is based on ZORBAX 5 μm silica particles. 460 
Add to Cart
  • Inner Diameter (ID)
  • 3 mm
  • Length
  • 50 mm
  • Phase
  • SCX
  • UNSPSC Code
  • 41115711
  • Brand
  • ZORBAX
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 80 °C
  • Part Number Application
  • Peptides Proteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-7
  • Pore Size
  • 300 Å
  • Pressure Rating
  • 350 bar
  • Separation Mode
  • Ion Exchange (IEX)
  • Shipping Solvent
  • Phosphate Buffer
  • Technique
  • LC
AGIL860700-704 ZORBAX 300Å SCX, 2.1 x 50 mm, 5 µm. A strong cation exchange HPLC column that is based on ZORBAX 5 μm silica particles. 460 
Add to Cart
  • Inner Diameter (ID)
  • 2.1 mm
  • Length
  • 50 mm
  • Phase
  • SCX
  • UNSPSC Code
  • 41115711
  • Brand
  • ZORBAX
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 80 °C
  • Part Number Application
  • Peptides Proteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-7
  • Pore Size
  • 300 Å
  • Pressure Rating
  • 350 bar
  • Separation Mode
  • Ion Exchange (IEX)
  • Shipping Solvent
  • Phosphate Buffer
  • Technique
  • LC
AGIL880952-203 ZORBAX 70Å SAX, 9.4 x 250 mm, 5 µm. A strong anion exchange HPLC semi-prep column that is based on ZORBAX 5 μm silica particles. The pore size of the strong anion exchange column is 70Å and more suited for small molecule separations. 1492 
Add to Cart
  • Inner Diameter (ID)
  • 9.4 mm
  • Length
  • 250 mm
  • Phase
  • SAX
  • UNSPSC Code
  • 41115711
  • Brand
  • ZORBAX
  • Hardware
  • SS
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 80 °C
  • Part Number Application
  • Peptides Proteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-7
  • Pore Size
  • 70 Å
  • Pressure Rating
  • 350 bar
  • Separation Mode
  • Ion Exchange (IEX)
  • Shipping Solvent
  • Phosphate Buffer
  • Technique
  • LC
AGIL880952-703 ZORBAX 70Å SAX, 4.6 x 250 mm, 5 µm. A strong anion exchange HPLC column that is based on ZORBAX 5 μm silica particles. The pore size of the strong anion exchange column is 70Å and more suited for small molecule separations. 612 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 250 mm
  • Phase
  • SAX
  • UNSPSC Code
  • 41115711
  • Brand
  • ZORBAX
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 80 °C
  • Part Number Application
  • Peptides Proteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-7
  • Pore Size
  • 70 Å
  • Pressure Rating
  • 350 bar
  • Separation Mode
  • Ion Exchange (IEX)
  • Shipping Solvent
  • Phosphate Buffer
  • Technique
  • LC
AGIL880952-704 ZORBAX 300Å SCX, 4.6 x 250 mm, 5 µm. A strong cation exchange HPLC column that is based on ZORBAX 5 μm silica particles. 702 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 250 mm
  • Phase
  • SCX
  • UNSPSC Code
  • 41115711
  • Brand
  • ZORBAX
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 80 °C
  • Part Number Application
  • Peptides Proteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-7
  • Pore Size
  • 300 Å
  • Pressure Rating
  • 350 bar
  • Separation Mode
  • Ion Exchange (IEX)
  • Shipping Solvent
  • Phosphate Buffer
  • Technique
  • LC
AGIL880952-714 ZORBAX 300Å SCX, 4.6 x 250 mm, 5 µm, SP. A strong cation exchange HPLC column that is based on ZORBAX 5 μm silica particles. 702 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 250 mm
  • Phase
  • SCX
  • UNSPSC Code
  • 41115711
  • Brand
  • ZORBAX
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 80 °C
  • Part Number Application
  • Peptides Proteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-7
  • Pore Size
  • 300 Å
  • Pressure Rating
  • 350 bar
  • Separation Mode
  • Ion Exchange (IEX)
  • Shipping Solvent
  • Phosphate Buffer
  • Technique
  • LC
AGIL883700-704 ZORBAX 300Å SCX, 2.1 x 150 mm, 5 µm. A strong cation exchange HPLC column that is based on ZORBAX 5 μm silica particles. 650 
Add to Cart
  • Inner Diameter (ID)
  • 2.1 mm
  • Length
  • 150 mm
  • Phase
  • SCX
  • UNSPSC Code
  • 41115711
  • Brand
  • ZORBAX
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 80 °C
  • Part Number Application
  • Peptides Proteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-7
  • Pore Size
  • 300 Å
  • Pressure Rating
  • 350 bar
  • Separation Mode
  • Ion Exchange (IEX)
  • Shipping Solvent
  • Phosphate Buffer
  • Technique
  • LC

Overview

The small molecule column portfolio includes state-of-the-art superficially porous InfinityLab Poroshell 120 columns as well as traditional fully porous ZORBAX, Polaris, and Pursuit columns.

When you choose Agilent small molecule LC columns, you get more than just a dependable product. You also get unmatched technical support from the world’s largest chromatography supplier.


Agilent gel permeation chromatography (GPC) and size exclusion chromatography (SEC) columns and standards have been the top-selling in the polymer industry for over 40 years. GPC and SEC is used to determine the molecular weight and size distribution of macromolecules. SEC and GPC columns generate accurate, reliable data for critical polymer parameters, including dispersity (PDI), molecular weight mass average (Mw), number average (Mn), and z-average (Mz).


The importance of understanding the attributes of a biologic drug, and the processes used to create it, cannot be underestimated.  Agilent AdvanceBio LC columns are designed and produced to provide results you can be sure of when analyzing highly complex biotherapeutic molecules and monitoring their purity, potency, and other critical quality attributes.



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