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Agilent offers the largest, most modern liquid chromatography (LC) column portfolios for small molecule analysis, with columns suitable for nearly all separation modes and applications.


Whether you are performing conventional or ultra-fast chromatography, separating biomolecules, or analyzing complex compounds, the industry’s highest-performing compounds deliver fast, reproducible results – all engineered with unparalleled quality and reliability.

Catalog No. Product Net Price
AGIL820212-928 ZORBAX Bonus-RP, 15.8 x 10 mm, guard cartridge (PrepHT), 5 µm, 2/PK (use with end-fitting 820444-901, or standalone hardware kit 420420-901) 341 
Add to Cart
  • Inner Diameter (ID)
  • 17 mm
  • Length
  • 8 mm
  • Phase
  • Bonus-RP
  • UNSPSC Code
  • 41115711
  • Brand
  • ZORBAX
  • Carbon Load
  • 9.5 %
  • Endcapped
  • Triple
  • Guard Column
  • Yes
  • Hardware
  • Cartridge
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 40 °C from pH 8-9 60 °C up to pH 8 40from pH 8-9 °C60up to pH 8 °C
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 340 bar
  • Separation Mode
  • Reversed Phase
AGIL820212-930 ZORBAX Extend 80Å C18, 15.8 x 10 mm guard cartridge (PrepHT), 5 µm, 2/pk (use with end-fitting 820444-901, or standalone hardware kit 420420-901) 341 
Add to Cart
  • Inner Diameter (ID)
  • 16 mm
  • Length
  • 8 mm
  • Phase
  • Extend-C18
  • UNSPSC Code
  • 41115711
  • USP Designation
  • L1
  • Brand
  • ZORBAX
  • Carbon Load
  • 12.5 %
  • Endcapped
  • Double
  • Guard Column
  • Yes
  • Hardware
  • Cartridge
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 40 °C at pH 8-9 60 °C at pH 2-8 40 °C at pH 8-11.560 °C at pH 2-8
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-11.5
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 350 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
AGIL820212-933 ZORBAX StableBond, 15.8 x 10 mm, Aq guard cartridge (PrepHT), 5 µm, 2/PK. Use with end-fitting 820444-901, or standalone hardware kit 420420-901. 341 
Add to Cart
  • Inner Diameter (ID)
  • 16 mm
  • Length
  • 10 mm
  • Phase
  • SB-Aq
  • UNSPSC Code
  • 41115711
  • USP Designation
  • L96
  • Brand
  • ZORBAX
  • Endcapped
  • No
  • Guard Column
  • Yes
  • Hardware
  • Cartridge
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 40 °C at pH 6-8 80 °C at pH 1-6 40 °C at pH 6-880 °C at pH 1-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 340 bar
  • Separation Mode
  • Reversed Phase
AGIL868100-901 ZORBAX Bonus-RP, PrepHT cartridge, 21.2, 100 mm, 5 µm (use with hardware kit 820400-901) 3264 
Add to Cart
  • Inner Diameter (ID)
  • 21.2 mm
  • Length
  • 100 mm
  • Phase
  • Bonus-RP
  • UNSPSC Code
  • 41115711
  • USP Designation
  • L60
  • Brand
  • ZORBAX
  • Carbon Load
  • 9.5 %
  • Endcapped
  • Triple
  • Guard Column
  • Yes
  • Hardware
  • Cartridge
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 40 °C from pH 8-9 60 °C up to pH 8 40from pH 8-9 °C60up to pH 8 °C
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-9
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 340 bar
  • Separation Mode
  • Reversed Phase
AGIL870050-906 ZORBAX Rx, PrepHT cartridge, Rx-C8, 21.2, 50 mm, 7 µm (use with hardware kit 820400-901) 1598 
Add to Cart
  • Inner Diameter (ID)
  • 21.2 mm
  • Length
  • 50 mm
  • Phase
  • Rx-C8
  • UNSPSC Code
  • 41115709
  • Brand
  • ZORBAX
  • Carbon Load
  • 5.5 %
  • Endcapped
  • No
  • Guard Column
  • Yes
  • Hardware
  • Cartridge
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 40 °C at pH 6-8 80 °C at pH 1-6 40 °C at pH 6-880 °C at pH 1-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 340 bar
  • Separation Mode
  • Reversed Phase
AGIL870050-914 ZORBAX PrepHT StableBond Aq, 21.2 x 50 mm, 5 µm. 80Å, use with hardware kit 820400-901. 1454 
Add to Cart
  • Inner Diameter (ID)
  • 21.2 mm
  • Length
  • 50 mm
  • Phase
  • SB-Aq
  • UNSPSC Code
  • 41115711
  • USP Designation
  • L96
  • Brand
  • ZORBAX
  • Endcapped
  • No
  • Guard Column
  • Yes
  • Hardware
  • Cartridge
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 40 °C at pH 6-8 80 °C at pH 1-6 40 °C at pH 6-880 °C at pH 1-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 340 bar
  • Separation Mode
  • Reversed Phase
AGIL870100-906 ZORBAX Rx, PrepHT cartridge, Rx-C8, 21.2, 100 mm, 7 µm (use with hardware kit 820400-901) 2338 
Add to Cart
  • Inner Diameter (ID)
  • 21.2 mm
  • Length
  • 100 mm
  • Phase
  • Rx-C8
  • UNSPSC Code
  • 41115709
  • Brand
  • ZORBAX
  • Carbon Load
  • 5.5 %
  • Endcapped
  • No
  • Guard Column
  • Yes
  • Hardware
  • Cartridge
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 40 °C at pH 6-8 80 °C at pH 1-6 40 °C at pH 6-880 °C at pH 1-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 340 bar
  • Separation Mode
  • Reversed Phase
AGIL870100-914 ZORBAX PrepHT StableBond Aq, 21.2 x 100 mm, 5 µm. 80Å, use with hardware kit 820400-901. 2125 
Add to Cart
  • Inner Diameter (ID)
  • 21.2 mm
  • Length
  • 100 mm
  • Phase
  • SB-Aq
  • UNSPSC Code
  • 41115711
  • USP Designation
  • L96
  • Brand
  • ZORBAX
  • Endcapped
  • No
  • Guard Column
  • Yes
  • Hardware
  • Cartridge
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 40 °C at pH 6-8 80 °C at pH 1-6 40 °C at pH 6-880 °C at pH 1-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 340 bar
  • Separation Mode
  • Reversed Phase
AGIL870150-906 ZORBAX PrepHT StableBond C8, 21.2 x 150 mm, 5 µm. 80Å, use with hardware kit 820400-901. 3215 
Add to Cart
  • Inner Diameter (ID)
  • 21.2 mm
  • Length
  • 150 mm
  • Phase
  • SB-C8
  • UNSPSC Code
  • 41115709
  • Brand
  • ZORBAX
  • Carbon Load
  • 5.5 %
  • Endcapped
  • No
  • Guard Column
  • Yes
  • Hardware
  • Cartridge
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 40 °C at pH 6-8 80 °C at pH 1-6 40 °C at pH 6-880 °C at pH 1-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 340 bar
  • Separation Mode
  • Reversed Phase
AGIL870150-914 ZORBAX PrepHT StableBond Aq, 21.2 x 150 mm, 5 µm. 80Å, use with hardware kit 820400-901. 2921 
Add to Cart
  • Inner Diameter (ID)
  • 21.2 mm
  • Length
  • 150 mm
  • Phase
  • SB-Aq
  • UNSPSC Code
  • 41115711
  • USP Designation
  • L96
  • Brand
  • ZORBAX
  • Endcapped
  • No
  • Guard Column
  • Yes
  • Hardware
  • Cartridge
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 40 °C at pH 6-8 80 °C at pH 1-6 40 °C at pH 6-880 °C at pH 1-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 340 bar
  • Separation Mode
  • Reversed Phase

Overview

The small molecule column portfolio includes state-of-the-art superficially porous InfinityLab Poroshell 120 columns as well as traditional fully porous ZORBAX, Polaris, and Pursuit columns.

When you choose Agilent small molecule LC columns, you get more than just a dependable product. You also get unmatched technical support from the world’s largest chromatography supplier.


Agilent gel permeation chromatography (GPC) and size exclusion chromatography (SEC) columns and standards have been the top-selling in the polymer industry for over 40 years. GPC and SEC is used to determine the molecular weight and size distribution of macromolecules. SEC and GPC columns generate accurate, reliable data for critical polymer parameters, including dispersity (PDI), molecular weight mass average (Mw), number average (Mn), and z-average (Mz).


The importance of understanding the attributes of a biologic drug, and the processes used to create it, cannot be underestimated.  Agilent AdvanceBio LC columns are designed and produced to provide results you can be sure of when analyzing highly complex biotherapeutic molecules and monitoring their purity, potency, and other critical quality attributes.



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