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Agilent offers the largest, most modern liquid chromatography (LC) column portfolios for small molecule analysis, with columns suitable for nearly all separation modes and applications.


Whether you are performing conventional or ultra-fast chromatography, separating biomolecules, or analyzing complex compounds, the industry’s highest-performing compounds deliver fast, reproducible results – all engineered with unparalleled quality and reliability.

Catalog No. Product Net Price
AGIL880975-901 ZORBAX Rx-SIL, 80Å, 4.6 x 250 mm, 5µm, 400 bar pressure limit 706 
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  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 250 mm
  • Phase
  • Rx-SIL
  • UNSPSC Code
  • 41115711
  • USP Designation
  • L3
  • Agency Method
  • ASTM D5297
  • Brand
  • ZORBAX
  • Carbon Load
  • 0 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 0.8-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Normal Phase SFC
  • Shipping Solvent
  • Hexane
AGIL880975-905 ZORBAX StableBond CN, 4.6 x 250 mm, 5 µm, 400 bar. 80Å, 400 bar pressure limit. 711 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 250 mm
  • Phase
  • SB-CN
  • UNSPSC Code
  • 41115709
  • USP Designation
  • L10
  • Brand
  • ZORBAX
  • Carbon Load
  • 4 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC
  • Maximum Temperature
  • 40 °C at pH 6-8 80 °C at pH 1-6 40 °C at pH 6-880 °C at pH 1-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Normal Phase Reversed Phase SFC
  • Shipping Solvent
  • Methanol/Water
AGIL883700-905 ZORBAX StableBond CN, 2.1 x 150 mm, 5 µm, 400 bar. 80Å, 400 bar pressure limit. 648 
Add to Cart
  • Inner Diameter (ID)
  • 2.1 mm
  • Length
  • 150 mm
  • Phase
  • SB-CN
  • UNSPSC Code
  • 41115709
  • USP Designation
  • L10
  • Brand
  • ZORBAX
  • Carbon Load
  • 4 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC
  • Maximum Temperature
  • 40 °C at pH 6-8 80 °C at pH 1-6 40 °C at pH 6-880 °C at pH 1-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Normal Phase Reversed Phase SFC
  • Shipping Solvent
  • Methanol/Water
AGIL883952-705 ZORBAX Original CN, 70Å, 4.6 x 150 mm, 5 µm, 400 bar pressure limit 569 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 150 mm
  • Phase
  • Original CN
  • UNSPSC Code
  • 41115709
  • Brand
  • ZORBAX
  • Carbon Load
  • 7 %
  • Endcapped
  • Yes
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC
  • Maximum Temperature
  • 60 °C
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-7
  • Pore Size
  • 70 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Normal Phase NReversed Phase
AGIL883975-901 ZORBAX Rx-SIL, 80Å, 4.6 x 150 mm, 5µm, 400 bar pressure limit 645 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 150 mm
  • Phase
  • Rx-SIL
  • UNSPSC Code
  • 41115711
  • USP Designation
  • L3
  • Brand
  • ZORBAX
  • Carbon Load
  • 0 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 0.8-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Normal Phase SFC
  • Shipping Solvent
  • Hexane
AGIL959757-301 ZORBAX RRHD HILIC Plus, 95Å, 3.0 x 50 mm, 1.8 µm, 1200 bar 724 
Add to Cart
  • Inner Diameter (ID)
  • 3 mm
  • Length
  • 50 mm
  • Phase
  • HILIC Plus
  • UNSPSC Code
  • 41115709
  • USP Designation
  • L3
  • Brand
  • ZORBAX
  • Carbon Load
  • 0 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC UHPLC Low Dispersion U
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 1.8 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 0-8
  • Pore Size
  • 95 Å
  • Pressure Rating
  • 1200 bar
  • Separation Mode
  • HILIC Normal Phase SFC
  • Shipping Solvent
  • Acetonitrile/Water
AGIL959758-301 ZORBAX RRHD HILIC Plus, 95Å, 3.0 x 100 mm, 1.8 µm, 1200 bar 755 
Add to Cart
  • Inner Diameter (ID)
  • 3 mm
  • Length
  • 100 mm
  • Phase
  • HILIC Plus
  • UNSPSC Code
  • 41115709
  • USP Designation
  • L3
  • Brand
  • ZORBAX
  • Carbon Load
  • 0 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC UHPLC Low Dispersion U
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 1.8 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 0-8
  • Pore Size
  • 95 Å
  • Pressure Rating
  • 1200 bar
  • Separation Mode
  • HILIC Normal Phase SFC
  • Shipping Solvent
  • Acetonitrile/Water
AGIL959961-901 ZORBAX RR HILIC Plus, 95Å, 4.6 x 100 mm, 3.5 µm 620 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 100 mm
  • Phase
  • HILIC Plus
  • UNSPSC Code
  • 41115709
  • USP Designation
  • L3
  • Brand
  • ZORBAX
  • Carbon Load
  • 0 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 3.5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 0-8
  • Pore Size
  • 95 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • HILIC Normal Phase SFC
  • Shipping Solvent
  • Acetonitrile/Water
AGIL420420-901 Agilent Prep External Guard Hardware Kit 449 
Add to Cart
  • UNSPSC Code
  • 41115700
AGIL820212-911 ZORBAX GF-450, 15.8 x 10 mm, guard cartridge (PrepHT), 5 µm, 2/pk. Use with end-fitting 820444-901, or standalone hardware kit 420420-901. 541 
Add to Cart
  • Inner Diameter (ID)
  • 17 mm
  • Length
  • 8 mm
  • Phase
  • GF-450
  • UNSPSC Code
  • 41115711
  • Brand
  • ZORBAX
  • Guard Column
  • Yes
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 60 °C
  • Molecular Weight Lower Limit
  • 10000 Da
  • Part Number Application
  • Aggregate & Fragment Analysis PeptidesProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 3-8.5
  • Pore Size
  • 300 Å
  • Separation Mode
  • Size Exclusion (SEC)
  • Shipping Solvent
  • Phosphate Buffer
  • Technique
  • LC

Overview

The small molecule column portfolio includes state-of-the-art superficially porous InfinityLab Poroshell 120 columns as well as traditional fully porous ZORBAX, Polaris, and Pursuit columns.

When you choose Agilent small molecule LC columns, you get more than just a dependable product. You also get unmatched technical support from the world’s largest chromatography supplier.


Agilent gel permeation chromatography (GPC) and size exclusion chromatography (SEC) columns and standards have been the top-selling in the polymer industry for over 40 years. GPC and SEC is used to determine the molecular weight and size distribution of macromolecules. SEC and GPC columns generate accurate, reliable data for critical polymer parameters, including dispersity (PDI), molecular weight mass average (Mw), number average (Mn), and z-average (Mz).


The importance of understanding the attributes of a biologic drug, and the processes used to create it, cannot be underestimated.  Agilent AdvanceBio LC columns are designed and produced to provide results you can be sure of when analyzing highly complex biotherapeutic molecules and monitoring their purity, potency, and other critical quality attributes.



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