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Agilent offers the largest, most modern liquid chromatography (LC) column portfolios for small molecule analysis, with columns suitable for nearly all separation modes and applications.


Whether you are performing conventional or ultra-fast chromatography, separating biomolecules, or analyzing complex compounds, the industry’s highest-performing compounds deliver fast, reproducible results – all engineered with unparalleled quality and reliability.

Catalog No. Product Net Price
AGIL821725-938 ZORBAX RRHD HILIC Plus, 95Å, 2.1 mm, 1.8 μm, 1200 bar pressure limit, UHPLC guard, 3/pk 583 
Add to Cart
  • Inner Diameter (ID)
  • 2.1 mm
  • Length
  • 5 mm
  • Phase
  • HILIC Plus
  • UNSPSC Code
  • 41115709
  • USP Designation
  • L3
  • Brand
  • ZORBAX
  • Carbon Load
  • 0 %
  • Endcapped
  • No
  • Guard Column
  • Yes
  • Hardware
  • Conventional
  • LC Platform
  • HPLC UHPLC Low Dispersion U
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 1.8 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 0-8
  • Pore Size
  • 95 Å
  • Pressure Rating
  • 1200 bar
  • Separation Mode
  • HILIC Normal Phase SFC
  • Shipping Solvent
  • Acetonitrile/Water
AGIL860700-708 ZORBAX Original NH2, 70Å, 2.1 x 50 mm, 5 µm, 400 bar pressure limit 510 
Add to Cart
  • Inner Diameter (ID)
  • 2.1 mm
  • Length
  • 50 mm
  • Phase
  • Original NH2
  • UNSPSC Code
  • 41115711
  • Brand
  • ZORBAX
  • Carbon Load
  • 4 %
  • Endcapped
  • Yes
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC
  • Maximum Temperature
  • 60 °C
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-7
  • Pore Size
  • 70 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • HILIC Normal Phase SFC
  • Shipping Solvent
  • Hexane
AGIL877952-108 ZORBAX Original SIL, normal-phase, PrepHT cartridge, NH2, 21.2, 250 mm, 7 µm (use with hardware kit 820400-901) 3182 
Add to Cart
  • Inner Diameter (ID)
  • 21.2 mm
  • Length
  • 250 mm
  • Phase
  • Original NH2
  • UNSPSC Code
  • 41115711
  • Brand
  • ZORBAX
  • Carbon Load
  • 4 %
  • Endcapped
  • Yes
  • Guard Column
  • No
  • Hardware
  • Cartridge
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 60 °C
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 7 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-7
  • Pore Size
  • 70 Å
  • Pressure Rating
  • 340 bar
  • Separation Mode
  • HILIC Normal Phase SFC
AGIL880952-708 ZORBAX Original NH2, 70Å, 4.6 x 250 mm, 5 µm, 400 bar pressure limit 647 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 250 mm
  • Phase
  • Original NH2
  • UNSPSC Code
  • 41115711
  • Agency Method
  • ASTM D6379,ASTM D6591
  • Brand
  • ZORBAX
  • Carbon Load
  • 4 %
  • Endcapped
  • Yes
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC
  • Maximum Temperature
  • 60 °C
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-7
  • Pore Size
  • 70 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • HILIC Normal Phase SFC
  • Shipping Solvent
  • Hexane
AGIL883952-708 ZORBAX Original NH2, 70Å, 4.6 x 150 mm, 5 µm, 400 bar pressure limit 569 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 150 mm
  • Phase
  • Original NH2
  • UNSPSC Code
  • 41115711
  • Brand
  • ZORBAX
  • Carbon Load
  • 4 %
  • Endcapped
  • Yes
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC
  • Maximum Temperature
  • 60 °C
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-7
  • Pore Size
  • 70 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • HILIC Normal Phase SFC
  • Shipping Solvent
  • Hexane
AGIL959743-901 ZORBAX RR HILIC Plus, 95Å, 2.1 x 50 mm, 3.5 µm 481 
Add to Cart
  • Inner Diameter (ID)
  • 2.1 mm
  • Length
  • 50 mm
  • Phase
  • HILIC Plus
  • UNSPSC Code
  • 41115709
  • USP Designation
  • L3
  • Brand
  • ZORBAX
  • Carbon Load
  • 0 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 3.5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 0-8
  • Pore Size
  • 95 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • HILIC Normal Phase SFC
  • Shipping Solvent
  • Acetonitrile/Water
AGIL959757-901 ZORBAX RRHD HILIC Plus, 95Å, 2.1 x 50 mm, 1.8 µm, 1200 bar 724 
Add to Cart
  • Inner Diameter (ID)
  • 2.1 mm
  • Length
  • 50 mm
  • Phase
  • HILIC Plus
  • UNSPSC Code
  • 41115709
  • USP Designation
  • L3
  • Brand
  • ZORBAX
  • Carbon Load
  • 0 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC UHPLC Low Dispersion U
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 1.8 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 0-8
  • Pore Size
  • 95 Å
  • Pressure Rating
  • 1200 bar
  • Separation Mode
  • HILIC Normal Phase SFC
  • Shipping Solvent
  • Acetonitrile/Water
AGIL959758-901 ZORBAX RRHD HILIC Plus, 95Å, 2.1 x 100 mm, 1.8 µm, 1200 bar 755 
Add to Cart
  • Inner Diameter (ID)
  • 2.1 mm
  • Length
  • 100 mm
  • Phase
  • HILIC Plus
  • UNSPSC Code
  • 41115709
  • USP Designation
  • L3
  • Brand
  • ZORBAX
  • Carbon Load
  • 0 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC UHPLC Low Dispersion U
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 1.8 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 0-8
  • Pore Size
  • 95 Å
  • Pressure Rating
  • 1200 bar
  • Separation Mode
  • HILIC Normal Phase SFC
  • Shipping Solvent
  • Acetonitrile/Water
AGIL959759-901 ZORBAX RRHD HILIC Plus, 95Å, 2.1 x 150 mm, 1.8 µm, 1200 bar 921 
Add to Cart
  • Inner Diameter (ID)
  • 2.1 mm
  • Length
  • 150 mm
  • Phase
  • HILIC Plus
  • UNSPSC Code
  • 41115709
  • USP Designation
  • L3
  • Brand
  • ZORBAX
  • Carbon Load
  • 0 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC UHPLC Low Dispersion U
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 1.8 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 0-8
  • Pore Size
  • 95 Å
  • Pressure Rating
  • 1200 bar
  • Separation Mode
  • HILIC Normal Phase SFC
  • Shipping Solvent
  • Acetonitrile/Water
AGIL959793-901 ZORBAX RR HILIC Plus, 95Å,, 2.1 x 100 mm, 3.5 µm 626 
Add to Cart
  • Inner Diameter (ID)
  • 2.1 mm
  • Length
  • 100 mm
  • Phase
  • HILIC Plus
  • UNSPSC Code
  • 41115709
  • USP Designation
  • L3
  • Brand
  • ZORBAX
  • Carbon Load
  • 0 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 3.5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 0-8
  • Pore Size
  • 95 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • HILIC Normal Phase SFC
  • Shipping Solvent
  • Acetonitrile/Water

Overview

The small molecule column portfolio includes state-of-the-art superficially porous InfinityLab Poroshell 120 columns as well as traditional fully porous ZORBAX, Polaris, and Pursuit columns.

When you choose Agilent small molecule LC columns, you get more than just a dependable product. You also get unmatched technical support from the world’s largest chromatography supplier.


Agilent gel permeation chromatography (GPC) and size exclusion chromatography (SEC) columns and standards have been the top-selling in the polymer industry for over 40 years. GPC and SEC is used to determine the molecular weight and size distribution of macromolecules. SEC and GPC columns generate accurate, reliable data for critical polymer parameters, including dispersity (PDI), molecular weight mass average (Mw), number average (Mn), and z-average (Mz).


The importance of understanding the attributes of a biologic drug, and the processes used to create it, cannot be underestimated.  Agilent AdvanceBio LC columns are designed and produced to provide results you can be sure of when analyzing highly complex biotherapeutic molecules and monitoring their purity, potency, and other critical quality attributes.



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