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Agilent offers the largest, most modern liquid chromatography (LC) column portfolios for small molecule analysis, with columns suitable for nearly all separation modes and applications.


Whether you are performing conventional or ultra-fast chromatography, separating biomolecules, or analyzing complex compounds, the industry’s highest-performing compounds deliver fast, reproducible results – all engineered with unparalleled quality and reliability.

Catalog No. Product Net Price
AGIL820400-901 PrepHT cartridge hardware kit, 21.2 mm end fittings, 2/pk 391 
Add to Cart
  • Inner Diameter (ID)
  • 21.2 mm
  • UNSPSC Code
  • 41115716
  • Part Number Application Domain
  • Biopharma
  • Shipping Solvent
  • Phosphate Buffer
  • Technique
  • LC
AGIL820444-901 PrepHT Internal Guard Cartridge Hardware Kit 365 
Add to Cart
  • UNSPSC Code
  • 41115700
AGIL820950-911 ZORBAX Diol, 4.6 x 12.5 mm, 6 µm, guard cartridge (ZGC), 4/pk. Use with hardware kit 820999-901 310 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 13 mm
  • UNSPSC Code
  • 41115711
  • Brand
  • ZORBAX
  • Guard Column
  • Yes
  • Maximum Temperature
  • 60 °C
  • Part Number Application
  • Aggregate & Fragment Analysis PeptidesProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 6 µm
  • Separation Mode
  • Size Exclusion (SEC)
  • Shipping Solvent
  • Phosphate Buffer
  • Technique
  • LC
AGIL820999-901 High performance ZORBAX guard fittings kit (ZGC); includes low-volume guard holder, inlet end fitting (2), outlet end fitting with integrated column connector, and PEEK fingertight fitting, seals (2/pk) 278 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 12.5 mm
  • UNSPSC Code
  • 41115716
  • Brand
  • ZORBAX
  • Guard Column
  • Yes
  • Hardware
  • Kit
  • LC Platform
  • HPLC
  • Pressure Rating
  • 400 bar
AGIL840140-901 Semi-prep guard cartridge hardware kit, 9.4 mm ID cartridges (P system) 339 
Add to Cart
  • Inner Diameter (ID)
  • 9.4 mm
  • Length
  • 15 mm
  • UNSPSC Code
  • 41115700
  • Guard Column
  • Yes
  • Part Number Application Domain
  • Biopharma
  • Shipping Solvent
  • Phosphate Buffer
  • Technique
  • LC
AGIL877974-901 ZORBAX GF-250, 21.2 x 250 mm, 6 µm, cartridge (PrepHT). Use with hardware kit 820400-901 5697 
Add to Cart
  • Inner Diameter (ID)
  • 21.2 mm
  • Length
  • 250 mm
  • Phase
  • GF-250
  • UNSPSC Code
  • 41115711
  • Brand
  • ZORBAX
  • Hardware
  • SS
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 60 °C
  • Molecular Weight Lower Limit
  • 4000 Da
  • Part Number Application
  • Aggregate & Fragment Analysis PeptidesProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 6 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 3-8.5
  • Pore Size
  • 150 Å
  • Separation Mode
  • Size Exclusion (SEC)
  • Shipping Solvent
  • Phosphate Buffer
  • Technique
  • LC
AGIL877974-910 ZORBAX GF-450, 21.2 x 250 mm, 5 µm, cartridge (PrepHT). Use with hardware kit 820400-901 5697 
Add to Cart
  • Inner Diameter (ID)
  • 21.2 mm
  • Length
  • 250 mm
  • Phase
  • GF-450
  • UNSPSC Code
  • 41115711
  • Brand
  • ZORBAX
  • Hardware
  • SS
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 60 °C
  • Molecular Weight Lower Limit
  • 10000 Da
  • Part Number Application
  • Aggregate & Fragment Analysis PeptidesProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 6 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 3-8.5
  • Pore Size
  • 300 Å
  • Separation Mode
  • Size Exclusion (SEC)
  • Shipping Solvent
  • Phosphate Buffer
  • Technique
  • LC
AGIL884973-701 ZORBAX GF-250, 4.6 x 250 mm, 4 µm 991 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 250 mm
  • Phase
  • GF-250
  • UNSPSC Code
  • 41115711
  • Brand
  • ZORBAX
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 60 °C
  • Molecular Weight Lower Limit
  • 4000 Da
  • Part Number Application
  • Aggregate & Fragment Analysis PeptidesProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 4 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 3-8.5
  • Pore Size
  • 150 Å
  • Separation Mode
  • Size Exclusion (SEC)
  • Shipping Solvent
  • Phosphate Buffer
  • Technique
  • LC
AGIL884973-761 ZORBAX GF-250, 4.6 x 250 mm, 6 µm 991 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 250 mm
  • Phase
  • GF-250
  • UNSPSC Code
  • 41115711
  • Brand
  • ZORBAX
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 60 °C
  • Molecular Weight Lower Limit
  • 4000 Da
  • Part Number Application
  • Aggregate & Fragment Analysis PeptidesProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 6 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 3-8.5
  • Pore Size
  • 150 Å
  • Separation Mode
  • Size Exclusion (SEC)
  • Shipping Solvent
  • Phosphate Buffer
  • Technique
  • LC
AGIL820950-908 ZORBAX Original NH2, 70Å, 4.6 x 12.5 mm, 5 µm, 400 bar pressure limit, guard cartridge (ZGC), 4/pk 244 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 13 mm
  • Phase
  • Original NH2
  • UNSPSC Code
  • 41115711
  • Agency Method
  • ASTM D6379
  • Brand
  • ZORBAX
  • Carbon Load
  • 4 %
  • Endcapped
  • Yes
  • Guard Column
  • Yes
  • Hardware
  • Cartridge
  • LC Platform
  • HPLC
  • Maximum Temperature
  • 60 °C
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-7
  • Pore Size
  • 70 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • HILIC Normal Phase SFC

Overview

The small molecule column portfolio includes state-of-the-art superficially porous InfinityLab Poroshell 120 columns as well as traditional fully porous ZORBAX, Polaris, and Pursuit columns.

When you choose Agilent small molecule LC columns, you get more than just a dependable product. You also get unmatched technical support from the world’s largest chromatography supplier.


Agilent gel permeation chromatography (GPC) and size exclusion chromatography (SEC) columns and standards have been the top-selling in the polymer industry for over 40 years. GPC and SEC is used to determine the molecular weight and size distribution of macromolecules. SEC and GPC columns generate accurate, reliable data for critical polymer parameters, including dispersity (PDI), molecular weight mass average (Mw), number average (Mn), and z-average (Mz).


The importance of understanding the attributes of a biologic drug, and the processes used to create it, cannot be underestimated.  Agilent AdvanceBio LC columns are designed and produced to provide results you can be sure of when analyzing highly complex biotherapeutic molecules and monitoring their purity, potency, and other critical quality attributes.



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