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Agilent offers the largest, most modern liquid chromatography (LC) column portfolios for small molecule analysis, with columns suitable for nearly all separation modes and applications.


Whether you are performing conventional or ultra-fast chromatography, separating biomolecules, or analyzing complex compounds, the industry’s highest-performing compounds deliver fast, reproducible results – all engineered with unparalleled quality and reliability.

Catalog No. Product Net Price
AGIL827700-901 ZORBAX Rx-SIL, 80Å, 2.1 x 50 mm, 1.8 µm, 600 bar pressure limit 665 
Add to Cart
  • Inner Diameter (ID)
  • 2.1 mm
  • Length
  • 50 mm
  • Phase
  • Rx-SIL
  • UNSPSC Code
  • 41115711
  • USP Designation
  • L3
  • Brand
  • ZORBAX
  • Carbon Load
  • 0 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • UHPLC
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 1.8 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 0.8-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 600 bar
  • Separation Mode
  • Normal Phase SFC
  • Shipping Solvent
  • Hexane
AGIL827700-905 ZORBAX RRHT StableBond CN, 2.1 x 50 mm, 1.8 µm, 600 bar. 80Å, 600 bar pressure limit 655 
Add to Cart
  • Inner Diameter (ID)
  • 2.1 mm
  • Length
  • 50 mm
  • Phase
  • SB-CN
  • UNSPSC Code
  • 41115709
  • USP Designation
  • L10
  • Brand
  • ZORBAX
  • Carbon Load
  • 4 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • UHPLC
  • Maximum Temperature
  • 40 °C at pH 6-8 80 °C at pH 1-6 40 °C at pH 6-880 °C at pH 1-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 1.8 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 600 bar
  • Separation Mode
  • Normal Phase Reversed Phase SFC
  • Shipping Solvent
  • Acetonitrile/Water
AGIL827975-901 ZORBAX Rx-SIL, 80Å, 4.6 x 50 mm, 1.8 µm, 600 bar pressure limit 665 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 50 mm
  • Phase
  • Rx-SIL
  • UNSPSC Code
  • 41115711
  • USP Designation
  • L3
  • Brand
  • ZORBAX
  • Carbon Load
  • 0 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • UHPLC
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 1.8 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 0.8-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 600 bar
  • Separation Mode
  • Normal Phase SFC
  • Shipping Solvent
  • Hexane
AGIL828700-905 ZORBAX RRHT StableBond CN, 2.1 x 100 mm, 1.8 µm, 600 bar. 80Å, 600 bar pressure limit 739 
Add to Cart
  • Inner Diameter (ID)
  • 2.1 mm
  • Length
  • 100 mm
  • Phase
  • SB-CN
  • UNSPSC Code
  • 41115709
  • USP Designation
  • L10
  • Brand
  • ZORBAX
  • Carbon Load
  • 4 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • UHPLC
  • Maximum Temperature
  • 40 °C at pH 6-8 80 °C at pH 1-6 40 °C at pH 6-880 °C at pH 1-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 1.8 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 600 bar
  • Separation Mode
  • Normal Phase Reversed Phase SFC
  • Shipping Solvent
  • Acetonitrile/Water
AGIL828975-301 ZORBAX Rx-SIL, 80Å, 3.0 x 100 mm, 1.8 µm, 600 bar pressure limit 769 
Add to Cart
  • Inner Diameter (ID)
  • 3 mm
  • Length
  • 100 mm
  • Phase
  • Rx-SIL
  • UNSPSC Code
  • 41115711
  • USP Designation
  • L3
  • Brand
  • ZORBAX
  • Carbon Load
  • 0 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • UHPLC
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 1.8 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 0.8-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 600 bar
  • Separation Mode
  • Normal Phase SFC
  • Shipping Solvent
  • Hexane
AGIL828975-901 ZORBAX Rx-SIL, 80Å, 4.6 x 100 mm, 1.8 µm, 600 bar pressure limit 769 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 100 mm
  • Phase
  • Rx-SIL
  • UNSPSC Code
  • 41115711
  • USP Designation
  • L3
  • Brand
  • ZORBAX
  • Carbon Load
  • 0 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • UHPLC
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 1.8 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 0.8-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 600 bar
  • Separation Mode
  • Normal Phase SFC
  • Shipping Solvent
  • Hexane
AGIL828975-905 ZORBAX RRHT StableBond CN, 4.6 x 100 mm, 1.8 µm, 600 bar. 80Å, 600 bar pressure limit 739 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 100 mm
  • Phase
  • SB-CN
  • UNSPSC Code
  • 41115709
  • USP Designation
  • L10
  • Brand
  • ZORBAX
  • Carbon Load
  • 4 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • UHPLC
  • Maximum Temperature
  • 40 °C at pH 6-8 80 °C at pH 1-6 40 °C at pH 6-880 °C at pH 1-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 1.8 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 600 bar
  • Separation Mode
  • Normal Phase Reversed Phase SFC
  • Shipping Solvent
  • Acetonitrile/Water
AGIL829975-305 ZORBAX RRHT StableBond CN, 3.0 x 150 mm, 1.8 µm, 600 bar. 80Å, 600 bar pressure limit 921 
Add to Cart
  • Inner Diameter (ID)
  • 3 mm
  • Length
  • 150 mm
  • Phase
  • SB-CN
  • UNSPSC Code
  • 41115709
  • USP Designation
  • L10
  • Brand
  • ZORBAX
  • Carbon Load
  • 4 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • UHPLC
  • Maximum Temperature
  • 40 °C at pH 6-8 80 °C at pH 1-6 40 °C at pH 6-880 °C at pH 1-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 1.8 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 600 bar
  • Separation Mode
  • Normal Phase Reversed Phase SFC
  • Shipping Solvent
  • Acetonitrile/Water
AGIL857700-905 ZORBAX RRHD StableBond CN, 1.8 µm, 2.1 x 50 mm, 1200 bar. 80Å, 1200 bar pressure limit. 723 
Add to Cart
  • Inner Diameter (ID)
  • 2.1 mm
  • Length
  • 50 mm
  • Phase
  • SB-CN
  • UNSPSC Code
  • 41115709
  • USP Designation
  • L10
  • Brand
  • ZORBAX
  • Carbon Load
  • 4 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC UHPLC Low Dispersion U
  • Maximum Temperature
  • 40 °C at pH 6-8 80 °C at pH 1-6 40 °C at pH 6-880 °C at pH 1-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 1.8 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 1200 bar
  • Separation Mode
  • Normal Phase Reversed Phase SFC
  • Shipping Solvent
  • Acetonitrile/Water
AGIL859700-905 ZORBAX RRHD StableBond CN, 1.8 µm, 2.1 x 150 mm, 1200 bar. 80Å, 1200 bar pressure limit. 921 
Add to Cart
  • Inner Diameter (ID)
  • 2.1 mm
  • Length
  • 150 mm
  • Phase
  • SB-CN
  • UNSPSC Code
  • 41115709
  • USP Designation
  • L10
  • Brand
  • ZORBAX
  • Carbon Load
  • 4 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC UHPLC Low Dispersion U
  • Maximum Temperature
  • 40 °C at pH 6-8 80 °C at pH 1-6 40 °C at pH 6-880 °C at pH 1-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 1.8 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 1200 bar
  • Separation Mode
  • Normal Phase Reversed Phase SFC
  • Shipping Solvent
  • Acetonitrile/Water

Overview

The small molecule column portfolio includes state-of-the-art superficially porous InfinityLab Poroshell 120 columns as well as traditional fully porous ZORBAX, Polaris, and Pursuit columns.

When you choose Agilent small molecule LC columns, you get more than just a dependable product. You also get unmatched technical support from the world’s largest chromatography supplier.


Agilent gel permeation chromatography (GPC) and size exclusion chromatography (SEC) columns and standards have been the top-selling in the polymer industry for over 40 years. GPC and SEC is used to determine the molecular weight and size distribution of macromolecules. SEC and GPC columns generate accurate, reliable data for critical polymer parameters, including dispersity (PDI), molecular weight mass average (Mw), number average (Mn), and z-average (Mz).


The importance of understanding the attributes of a biologic drug, and the processes used to create it, cannot be underestimated.  Agilent AdvanceBio LC columns are designed and produced to provide results you can be sure of when analyzing highly complex biotherapeutic molecules and monitoring their purity, potency, and other critical quality attributes.



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