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Thin layer chromatography (TLC) and high performance thin layer chromatography (HPTLC), also called planar chromatography are based on a multistage distribution process involving

* Suitable adsorbents (the stationary phase) coated as a thin layer onto a suitable support / backing (e.g., glass plate, polyester or aluminum sheet)

* Solvents or solvent mixtures (the mobile phase or eluent)

* Sample molecules (analytes)

Today TLC has gained increasing importance as an analytical separation technique, which is probably due to effects of instrumentation and automation. At the same time the applicability of thin layer chromatography was enhanced by development of new adsorbents and backings. MACHEREY-NAGEL offers a versatile range of ready-to-use layers, which are the result of 50 years of continuous research and development.


Catalog No. Product Net Price
MN818147 HPTLC/TLC aluminum sheets, modified silica gel, ALUGRAM RP-18W UV254, 10x10 cm Special offer 
Add to Cart
  • Hazardous material
  • No
  • Method
  • Thin layer chromatography (HPTLC/TLC)
  • Brand
  • ALUGRAM
  • Phase
  • RP-18 W UV254
  • Mode
  • Reversed phase (RP)
  • Base material
  • Aluminum sheets coated with modified silica gel
  • Surface chemistry
  • Silica gel with octadecyl (C18, ODS, RP18) modification
  • Recommended application(s)
  • Aminophenols, Barbiturates, HPTLC, Nucleobases, Phthalates, Plasticizers, Polycyclic aromatic hydrocarbons (PAH), Preservatives, Reversed phase, Steroids, Tetracyclines, Wettable with water
  • Particle type
  • Fully porous particles (FPP)
  • Particle size
  • 2–10 µm
  • Particle shape
  • Irregular
  • pH stability
  • 2.0–10.0
  • Storage temperature
  • RT
MN818152 HPTLC/TLC aluminum sheets, modified silica gel, ALUGRAM RP-18W UV254, 5x10 cm Special offer 
Add to Cart
  • Hazardous material
  • No
  • Method
  • Thin layer chromatography (HPTLC/TLC)
  • Brand
  • ALUGRAM
  • Phase
  • RP-18 W UV254
  • Mode
  • Reversed phase (RP)
  • Base material
  • Aluminum sheets coated with modified silica gel
  • Surface chemistry
  • Silica gel with octadecyl (C18, ODS, RP18) modification
  • Recommended application(s)
  • Aminophenols, Barbiturates, HPTLC, Nucleobases, Phthalates, Plasticizers, Polycyclic aromatic hydrocarbons (PAH), Preservatives, Reversed phase, Steroids, Tetracyclines, Wettable with water
  • Particle type
  • Fully porous particles (FPP)
  • Particle size
  • 2–10 µm
  • Particle shape
  • Irregular
  • pH stability
  • 2.0–10.0
  • Storage temperature
  • RT
MN818240 HPTLC/TLC aluminum sheets, silica gel layer, ALUGRAM Xtra Nano-SIL G, 5x20 cm Special offer 
Add to Cart
  • Hazardous material
  • No
  • Method
  • Thin layer chromatography (HPTLC/TLC)
  • Brand
  • ALUGRAM Xtra
  • Phase
  • Xtra Nano-SIL G
  • Mode
  • Normal phase (NP)
  • Base material
  • Aluminum sheets coated with silica gel
  • Surface chemistry
  • Unmodified silica gel (SiOH)
  • Recommended application(s)
  • Aflatoxins, Alkaloids, Amines, Amino acids, Analgesics, Antibiotics, Hormones, Marihuana compounds, Normal phase (NP), Patulin, Steroids, Sweeteners, Vitamins
  • Particle type
  • Fully porous particles (FPP)
  • Particle size
  • 2–10 µm
  • Particle shape
  • Irregular
  • pH stability
  • 2.0–8.0
  • Storage temperature
  • RT
MN818241 HPTLC/TLC aluminum sheets, silica gel layer, ALUGRAM Xtra Nano-SIL G, 20x20 cm Special offer 
Add to Cart
  • Hazardous material
  • No
  • Method
  • Thin layer chromatography (HPTLC/TLC)
  • Brand
  • ALUGRAM Xtra
  • Phase
  • Xtra Nano-SIL G
  • Mode
  • Normal phase (NP)
  • Base material
  • Aluminum sheets coated with silica gel
  • Surface chemistry
  • Unmodified silica gel (SiOH)
  • Recommended application(s)
  • Aflatoxins, Alkaloids, Amines, Amino acids, Analgesics, Antibiotics, Hormones, Marihuana compounds, Normal phase (NP), Patulin, Steroids, Sweeteners, Vitamins
  • Particle type
  • Fully porous particles (FPP)
  • Particle size
  • 2–10 µm
  • Particle shape
  • Irregular
  • pH stability
  • 2.0–8.0
  • Storage temperature
  • RT
MN818342 HPTLC/TLC aluminum sheets, silica gel, ALUGRAM Xtra Nano-SIL G UV254, 5x20 cm Special offer 
Add to Cart
  • Hazardous material
  • No
  • Method
  • Thin layer chromatography (HPTLC/TLC)
  • Brand
  • ALUGRAM Xtra
  • Phase
  • Xtra Nano-SIL G UV254
  • Mode
  • Normal phase (NP)
  • Base material
  • Aluminum sheets coated with silica gel
  • Surface chemistry
  • Unmodified silica gel (SiOH)
  • Recommended application(s)
  • Aflatoxins, Alkaloids, Amines, Amino acids, Analgesics, Antibiotics, Hormones, Marihuana compounds, Normal phase (NP), Patulin, Steroids, Sweeteners, Vitamins
  • Particle type
  • Fully porous particles (FPP)
  • Particle size
  • 2–10 µm
  • Particle shape
  • Irregular
  • pH stability
  • 2.0–8.0
  • Storage temperature
  • RT
MN818343 HPTLC/TLC aluminum sheets, silica gel, ALUGRAM Xtra Nano-SIL G UV254, 20x20 cm Special offer 
Add to Cart
  • Hazardous material
  • No
  • Method
  • Thin layer chromatography (HPTLC/TLC)
  • Brand
  • ALUGRAM Xtra
  • Phase
  • Xtra Nano-SIL G UV254
  • Mode
  • Normal phase (NP)
  • Base material
  • Aluminum sheets coated with silica gel
  • Surface chemistry
  • Unmodified silica gel (SiOH)
  • Recommended application(s)
  • Aflatoxins, Alkaloids, Amines, Amino acids, Analgesics, Antibiotics, Hormones, Marihuana compounds, Normal phase (NP), Patulin, Steroids, Sweeteners, Vitamins
  • Particle type
  • Fully porous particles (FPP)
  • Particle size
  • 2–10 µm
  • Particle shape
  • Irregular
  • pH stability
  • 2.0–8.0
  • Storage temperature
  • RT
MN818432 HPTLC/TLC aluminum sheets, concentrating zone, ALUGRAM Xtra Nano-SILGUR, 10x10cm Special offer 
Add to Cart
  • Hazardous material
  • No
  • Method
  • Thin layer chromatography (HPTLC/TLC)
  • Brand
  • ALUGRAM Xtra
  • Phase
  • Xtra Nano-SILGUR
  • Mode
  • Normal phase (NP)
  • Base material
  • Aluminum sheets coated with silica gel and kieselguhr
  • Surface chemistry
  • Concentrating zone (kieselguhr, diatomaceous earth or diatomite), Unmodified silica gel (SiOH)
  • Recommended application(s)
  • Aflatoxins, Alkaloids, Amines, Amino acids, Analgesics, Antibiotics, Hormones, Marihuana compounds, Normal phase (NP), Patulin, Steroids, Sweeteners, Vitamins
  • Particle type
  • Fully porous particles (FPP)
  • Particle size
  • 2–10 µm
  • Particle shape
  • Irregular
  • pH stability
  • 2.0–8.0
  • Storage temperature
  • RT
MN818442 HPTLC/TLC aluminum sheets, conc. zone, ALUGRAM Xtra Nano-SILGUR UV254, 10x10 cm Special offer 
Add to Cart
  • Hazardous material
  • No
  • Method
  • Thin layer chromatography (HPTLC/TLC)
  • Brand
  • ALUGRAM Xtra
  • Phase
  • Xtra Nano-SILGUR UV254
  • Mode
  • Normal phase (NP)
  • Base material
  • Aluminum sheets coated with silica gel and kieselguhr
  • Surface chemistry
  • Concentrating zone (kieselguhr, diatomaceous earth or diatomite), Unmodified silica gel (SiOH)
  • Recommended application(s)
  • Aflatoxins, Alkaloids, Amines, Amino acids, Analgesics, Antibiotics, Hormones, Marihuana compounds, Normal phase (NP), Patulin, Steroids, Sweeteners, Vitamins
  • Particle type
  • Fully porous particles (FPP)
  • Particle size
  • 2–10 µm
  • Particle shape
  • Irregular
  • pH stability
  • 2.0–8.0
  • Storage temperature
  • RT
MN818141 HPTLC/TLC aluminum sheets, silica gel layer, ALUGRAM Nano-SIL G, 20x20 cm Special offer 
Add to Cart
  • Hazardous material
  • No
  • Method
  • Thin layer chromatography (HPTLC/TLC)
  • Brand
  • ALUGRAM
  • Phase
  • Nano-SIL G
  • Mode
  • Normal phase (NP)
  • Base material
  • Aluminum sheets coated with silica gel
  • Surface chemistry
  • Unmodified silica gel (SiOH)
  • Recommended application(s)
  • Aflatoxins, Alkaloids, Amines, Amino acids, Analgesics, Antibiotics, Hormones, Marihuana compounds, Normal phase (NP), Patulin, Steroids, Sweeteners, Vitamins
  • Particle type
  • Fully porous particles (FPP)
  • Particle size
  • 2–10 µm
  • Particle shape
  • Irregular
  • pH stability
  • 2.0–8.0
  • Storage temperature
  • RT
MN818143 HPTLC/TLC aluminum sheets, silica gel layer, ALUGRAM Nano-SIL G UV254, 20x20 cm Special offer 
Add to Cart
  • Hazardous material
  • No
  • Method
  • Thin layer chromatography (HPTLC/TLC)
  • Brand
  • ALUGRAM
  • Phase
  • Nano-SIL G UV254
  • Mode
  • Normal phase (NP)
  • Base material
  • Aluminum sheets coated with silica gel
  • Surface chemistry
  • Unmodified silica gel (SiOH)
  • Recommended application(s)
  • Aflatoxins, Alkaloids, Amines, Amino acids, Analgesics, Antibiotics, Hormones, Marihuana compounds, Normal phase (NP), Patulin, Steroids, Sweeteners, Vitamins
  • Particle type
  • Fully porous particles (FPP)
  • Particle size
  • 2–10 µm
  • Particle shape
  • Irregular
  • pH stability
  • 2.0–8.0
  • Storage temperature
  • RT

Overview

The success of thin layer chromatography as a highly efficient microanalytical separation method is based on a large number of advantageous properties:


High sample throughput in a short time

Suitable for screening tests

Pilot procedure for HPLC and Flash chromatography

After separation the analytical information can be stored for a longer period of time (the TLC ready-to-use layer acts as storage medium for data)

Separated substances can be subjected to subsequent analytical procedures (e.g., IR, MS) at a later date

Rapid and cost-efficient optimization of the separation due to easy change of mobile and stationary phase



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