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Agilent offers the largest, most modern liquid chromatography (LC) column portfolios for small molecule analysis, with columns suitable for nearly all separation modes and applications.


Whether you are performing conventional or ultra-fast chromatography, separating biomolecules, or analyzing complex compounds, the industry’s highest-performing compounds deliver fast, reproducible results – all engineered with unparalleled quality and reliability.

Catalog No. Product Net Price
AGIL5190-2404 Agilent Bio MAb, NP3, 4 x 10 mm, guard. This HPLC guard column has a densely packed weak cation exchange layer designed for monoclonal antibody separations. The particles are nonporous and promote higher resolution and faster separations. 689 
Add to Cart
  • Inner Diameter (ID)
  • 4 mm
  • Length
  • 10 mm
  • Phase
  • WCX
  • UNSPSC Code
  • 41115711
  • Brand
  • Agilent Bio MAb
  • Guard Column
  • Yes
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 80 °C
  • Part Number Application
  • Charge Variant Analysis PeptidesProteinsmAbs
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 3 µm
  • Particle Type
  • Non-porous
  • pH Range
  • 2-12
  • Pressure Rating
  • 551 bar
  • Separation Mode
  • Ion Exchange (IEX)
  • Shipping Solvent
  • Phosphate Buffer
  • Technique
  • LC
AGIL5190-2405 Agilent Bio MAb, NP5, 4.6 x 250 mm. This HPLC column has a densely packed weak cation exchange layer designed for monoclonal antibody separations. The particles are nonporous and promote higher resolution and faster separations. 1818 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 250 mm
  • Phase
  • WCX
  • UNSPSC Code
  • 41115711
  • Brand
  • Agilent Bio MAb
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 80 °C
  • Part Number Application
  • Charge Variant Analysis PeptidesProteinsmAbs
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 5 µm
  • Particle Type
  • Non-porous
  • pH Range
  • 2-12
  • Pressure Rating
  • 413 bar
  • Separation Mode
  • Ion Exchange (IEX)
  • Shipping Solvent
  • Phosphate Buffer
  • Technique
  • LC
AGIL5190-2406 Agilent Bio MAb, NP5, 4 x 10 mm, guard. This HPLC guard column has a densely packed weak cation exchange layer designed for monoclonal antibody separations. The particles are nonporous and promote higher resolution and faster separations. 618 
Add to Cart
  • Inner Diameter (ID)
  • 4 mm
  • Length
  • 10 mm
  • Phase
  • WCX
  • UNSPSC Code
  • 41115711
  • Brand
  • Agilent Bio MAb
  • Guard Column
  • Yes
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 80 °C
  • Part Number Application
  • Charge Variant Analysis PeptidesProteinsmAbs
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 5 µm
  • Particle Type
  • Non-porous
  • pH Range
  • 2-12
  • Pressure Rating
  • 413 bar
  • Separation Mode
  • Ion Exchange (IEX)
  • Shipping Solvent
  • Phosphate Buffer
  • Technique
  • LC
AGIL5190-2407 Agilent Bio MAb, NP5, 4.6 x 250 mm, PEEK. This HPLC column has a densely packed weak cation exchange layer designed for monoclonal antibody separations. The column is PEEK-lined to couple with bio-compatible LC systems. 2037 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 250 mm
  • Phase
  • WCX
  • UNSPSC Code
  • 41115711
  • Brand
  • Agilent Bio MAb
  • Hardware
  • PEEK
  • LC Platform
  • BioInert
  • Maximum Temperature
  • 80 °C
  • Part Number Application
  • Charge Variant Analysis PeptidesProteinsmAbs
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 5 µm
  • Particle Type
  • Non-porous
  • pH Range
  • 2-12
  • Pressure Rating
  • 413 bar
  • Separation Mode
  • Ion Exchange (IEX)
  • Shipping Solvent
  • Phosphate Buffer
  • Technique
  • LC
AGIL5190-2408 Agilent Bio MAb, NP5, 4.6 x 50 mm, PEEK. This HPLC column has a densely packed weak cation exchange layer designed for monoclonal antibody separations. The column is PEEK-lined to couple with bio-compatible LC systems. 1092 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 50 mm
  • Phase
  • WCX
  • UNSPSC Code
  • 41115711
  • Brand
  • Agilent Bio MAb
  • Hardware
  • PEEK
  • LC Platform
  • BioInert
  • Maximum Temperature
  • 80 °C
  • Part Number Application
  • Charge Variant Analysis PeptidesProteinsmAbs
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 5 µm
  • Particle Type
  • Non-porous
  • pH Range
  • 2-12
  • Pressure Rating
  • 413 bar
  • Separation Mode
  • Ion Exchange (IEX)
  • Shipping Solvent
  • Phosphate Buffer
  • Technique
  • LC
AGIL5190-2411 Agilent Bio MAb, NP5, 2.1 x 250 mm, PEEK. This HPLC column has a densely packed weak cation exchange layer designed for monoclonal antibody separations. The column is PEEK-lined to couple with bio-compatible LC systems. 2220 
Add to Cart
  • Inner Diameter (ID)
  • 2.1 mm
  • Length
  • 250 mm
  • Phase
  • WCX
  • UNSPSC Code
  • 41115711
  • Brand
  • Agilent Bio MAb
  • Hardware
  • PEEK
  • LC Platform
  • BioInert
  • Maximum Temperature
  • 80 °C
  • Part Number Application
  • Charge Variant Analysis PeptidesProteinsmAbs
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 5 µm
  • Particle Type
  • Non-porous
  • pH Range
  • 2-12
  • Pressure Rating
  • 413 bar
  • Separation Mode
  • Ion Exchange (IEX)
  • Shipping Solvent
  • Phosphate Buffer
  • Technique
  • LC
AGIL5190-2412 Agilent Bio MAb, NP5, 2.1 x 50 mm, PEEK. This HPLC column has a densely packed weak cation exchange layer designed for monoclonal antibody separations. The column is PEEK-lined to couple with bio-compatible LC systems. 1092 
Add to Cart
  • Inner Diameter (ID)
  • 2.1 mm
  • Length
  • 50 mm
  • Phase
  • WCX
  • UNSPSC Code
  • 41115711
  • Brand
  • Agilent Bio MAb
  • Hardware
  • PEEK
  • LC Platform
  • BioInert
  • Maximum Temperature
  • 80 °C
  • Part Number Application
  • Charge Variant Analysis PeptidesProteinsmAbs
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 5 µm
  • Particle Type
  • Non-porous
  • pH Range
  • 2-12
  • Pressure Rating
  • 413 bar
  • Separation Mode
  • Ion Exchange (IEX)
  • Shipping Solvent
  • Phosphate Buffer
  • Technique
  • LC
AGIL5190-2413 Agilent Bio MAb, NP10, 4.6 x 250 mm. This HPLC column has a densely packed weak cation exchange layer designed for monoclonal antibody separations. The particles are nonporous and promote higher resolution and faster separations. 1559 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 250 mm
  • Phase
  • WCX
  • UNSPSC Code
  • 41115711
  • Brand
  • Agilent Bio MAb
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 80 °C
  • Part Number Application
  • Charge Variant Analysis PeptidesProteinsmAbs
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 10 µm
  • Particle Type
  • Non-porous
  • pH Range
  • 2-12
  • Pressure Rating
  • 275 bar
  • Separation Mode
  • Ion Exchange (IEX)
  • Shipping Solvent
  • Phosphate Buffer
  • Technique
  • LC
AGIL5190-2414 Agilent Bio MAb, NP10, 4 x 10 mm, guard. This HPLC guard column has a densely packed weak cation exchange layer designed for monoclonal antibody separations. The particles are nonporous and promote higher resolution and faster separations. 545 
Add to Cart
  • Inner Diameter (ID)
  • 4 mm
  • Length
  • 10 mm
  • Phase
  • WCX
  • UNSPSC Code
  • 41115711
  • Brand
  • Agilent Bio MAb
  • Guard Column
  • Yes
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 80 °C
  • Part Number Application
  • Charge Variant Analysis PeptidesProteinsmAbs
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 10 µm
  • Particle Type
  • Non-porous
  • pH Range
  • 2-12
  • Pressure Rating
  • 275 bar
  • Separation Mode
  • Ion Exchange (IEX)
  • Shipping Solvent
  • Phosphate Buffer
  • Technique
  • LC
AGIL5190-2415 Agilent Bio MAb, NP10, 4.6 x 250 mm, PEEK. This HPLC column has a densely packed weak cation exchange layer designed for monoclonal antibody separations. The column is PEEK-lined to couple with bio-compatible LC systems. 1748 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 250 mm
  • Phase
  • WCX
  • UNSPSC Code
  • 41115711
  • Brand
  • Agilent Bio MAb
  • Hardware
  • PEEK
  • LC Platform
  • BioInert
  • Maximum Temperature
  • 80 °C
  • Part Number Application
  • Charge Variant Analysis PeptidesProteinsmAbs
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 10 µm
  • Particle Type
  • Non-porous
  • pH Range
  • 2-12
  • Pressure Rating
  • 275 bar
  • Separation Mode
  • Ion Exchange (IEX)
  • Shipping Solvent
  • Phosphate Buffer
  • Technique
  • LC

Overview

The small molecule column portfolio includes state-of-the-art superficially porous InfinityLab Poroshell 120 columns as well as traditional fully porous ZORBAX, Polaris, and Pursuit columns.

When you choose Agilent small molecule LC columns, you get more than just a dependable product. You also get unmatched technical support from the world’s largest chromatography supplier.


Agilent gel permeation chromatography (GPC) and size exclusion chromatography (SEC) columns and standards have been the top-selling in the polymer industry for over 40 years. GPC and SEC is used to determine the molecular weight and size distribution of macromolecules. SEC and GPC columns generate accurate, reliable data for critical polymer parameters, including dispersity (PDI), molecular weight mass average (Mw), number average (Mn), and z-average (Mz).


The importance of understanding the attributes of a biologic drug, and the processes used to create it, cannot be underestimated.  Agilent AdvanceBio LC columns are designed and produced to provide results you can be sure of when analyzing highly complex biotherapeutic molecules and monitoring their purity, potency, and other critical quality attributes.



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