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Agilent offers the largest, most modern liquid chromatography (LC) column portfolios for small molecule analysis, with columns suitable for nearly all separation modes and applications.


Whether you are performing conventional or ultra-fast chromatography, separating biomolecules, or analyzing complex compounds, the industry’s highest-performing compounds deliver fast, reproducible results – all engineered with unparalleled quality and reliability.

Catalog No. Product Net Price
AGIL5190-6877 Agilent Bio WAX, NP5, 21.2 x 250 mm, 5 µm. A weak anion exchange prep sized HPLC column with nonporous particles. Particle size is 5 μm. Nonporous particles are best for efficient mass transfer and high resolution separations. 22505 
Add to Cart
  • Inner Diameter (ID)
  • 21.2 mm
  • Length
  • 250 mm
  • Phase
  • WAX
  • UNSPSC Code
  • 41115709
  • Brand
  • Agilent Bio WAX
  • Hardware
  • SS
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 80 °C
  • Part Number Application
  • Monoclonal Antibodies (mABs) Proteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 5 µm
  • Particle Type
  • Non-porous
  • pH Range
  • 2-12
  • Pressure Rating
  • 413 bar
  • Separation Mode
  • Ion Exchange (IEX)
  • Shipping Solvent
  • Phosphate Buffer
  • Technique
  • LC
AGIL5190-6878 Agilent Bio SCX, NP5, 10 x 250 mm, 5 µm. A strong cation exchange semi-prep sized HPLC column with nonporous particles. Particle size is 5 μm. Nonporous particles are best for efficient mass transfer and high resolution separations. 6930 
Add to Cart
  • Inner Diameter (ID)
  • 10 mm
  • Length
  • 250 mm
  • Phase
  • SCX
  • UNSPSC Code
  • 41115709
  • Brand
  • Agilent Bio SCX
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 80 °C
  • Part Number Application
  • Charge Variant Analysis PeptidesProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 5 µm
  • Particle Type
  • Non-porous
  • pH Range
  • 2-12
  • Pressure Rating
  • 413 bar
  • Separation Mode
  • Ion Exchange (IEX)
  • Shipping Solvent
  • Phosphate Buffer
  • Technique
  • LC
AGIL5190-6879 Agilent Bio SCX, NP5, 21.2 x 250 mm, 5 µm. A strong cation exchange prep sized HPLC column with nonporous particles. Particle size is 5 μm. Nonporous particles are best for efficient mass transfer and high resolution separations. 22505 
Add to Cart
  • Inner Diameter (ID)
  • 21.2 mm
  • Length
  • 250 mm
  • Phase
  • SCX
  • UNSPSC Code
  • 41115709
  • Brand
  • Agilent Bio SCX
  • Hardware
  • SS
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 80 °C
  • Part Number Application
  • Charge Variant Analysis PeptidesProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 5 µm
  • Particle Type
  • Non-porous
  • pH Range
  • 2-12
  • Pressure Rating
  • 413 bar
  • Separation Mode
  • Ion Exchange (IEX)
  • Shipping Solvent
  • Phosphate Buffer
  • Technique
  • LC
AGIL5190-6880 Agilent Bio WCX, NP5, 10 x 250 mm, 5 µm. A weak cation exchange semi-prep sized HPLC column with nonporous particles. Particle size is 5 μm. Nonporous particles are best for efficient mass transfer and high resolution separations. 6930 
Add to Cart
  • Inner Diameter (ID)
  • 10 mm
  • Length
  • 250 mm
  • Phase
  • WCX
  • UNSPSC Code
  • 41115709
  • Brand
  • Agilent Bio WCX
  • Hardware
  • SS
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 80 °C
  • Part Number Application
  • Charge Variant Analysis PeptidesProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 5 µm
  • Particle Type
  • Non-porous
  • pH Range
  • 2-12
  • Pressure Rating
  • 413 bar
  • Separation Mode
  • Ion Exchange (IEX)
  • Shipping Solvent
  • Phosphate Buffer
  • Technique
  • LC
AGIL5190-6881 Agilent Bio WCX, NP5, 21.2 x 250 mm, 5 µm. A weak cation exchange prep sized HPLC column with nonporous particles. Particle size is 5 μm. Nonporous particles are best for efficient mass transfer and high resolution separations. 22505 
Add to Cart
  • Inner Diameter (ID)
  • 21.2 mm
  • Length
  • 250 mm
  • Phase
  • WCX
  • UNSPSC Code
  • 41115709
  • Brand
  • Agilent Bio WCX
  • Hardware
  • SS
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 80 °C
  • Part Number Application
  • Charge Variant Analysis PeptidesProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 5 µm
  • Particle Type
  • Non-porous
  • pH Range
  • 2-12
  • Pressure Rating
  • 413 bar
  • Separation Mode
  • Ion Exchange (IEX)
  • Shipping Solvent
  • Phosphate Buffer
  • Technique
  • LC
AGIL5190-6882 Agilent Bio SAX, NP5, 10 x 250 mm, 5 µm. A strong anion exchange semi-prep sized HPLC column with nonporous particles. Particle size is 5 μm. Nonporous particles are best for efficient mass transfer and high resolution separations. 6930 
Add to Cart
  • Inner Diameter (ID)
  • 10 mm
  • Length
  • 250 mm
  • Phase
  • SAX
  • UNSPSC Code
  • 41115709
  • Brand
  • Agilent Bio SAX
  • Hardware
  • SS
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 80 °C
  • Part Number Application
  • Monoclonal Antibodies (mABs) Proteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 5 µm
  • Particle Type
  • Non-porous
  • pH Range
  • 2-12
  • Pressure Rating
  • 413 bar
  • Separation Mode
  • Ion Exchange (IEX)
  • Shipping Solvent
  • Phosphate Buffer
  • Technique
  • LC
AGIL5190-6883 Agilent Bio SAX, NP5, 21.2 x 250 mm, 5 µm. A strong anion exchange prep sized HPLC column with nonporous particles. Particle size is 5 μm. Nonporous particles are best for efficient mass transfer and high resolution separations. 22505 
Add to Cart
  • Inner Diameter (ID)
  • 21.2 mm
  • Length
  • 250 mm
  • Phase
  • SAX
  • UNSPSC Code
  • 41115709
  • Brand
  • Agilent Bio SAX
  • Hardware
  • SS
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 80 °C
  • Part Number Application
  • Monoclonal Antibodies (mABs) Proteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 5 µm
  • Particle Type
  • Non-porous
  • pH Range
  • 2-12
  • Pressure Rating
  • 413 bar
  • Separation Mode
  • Ion Exchange (IEX)
  • Shipping Solvent
  • Phosphate Buffer
  • Technique
  • LC
AGIL5190-2401 Agilent Bio MAb, NP1.7, 4.6 x 50 mm. This HPLC column has a densely packed weak cation exchange layer designed for monoclonal antibody separations. The particles are nonporous and promote higher resolution and faster separations. 1530 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 50 mm
  • Phase
  • WCX
  • UNSPSC Code
  • 41115711
  • Brand
  • Agilent Bio MAb
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 80 °C
  • Part Number Application
  • Charge Variant Analysis PeptidesProteinsmAbs
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 1.7 µm
  • Particle Type
  • Non-porous
  • pH Range
  • 2-12
  • Pressure Rating
  • 689 bar
  • Separation Mode
  • Ion Exchange (IEX)
  • Shipping Solvent
  • Phosphate Buffer
  • Technique
  • LC
AGIL5190-2402 Agilent Bio MAb, NP1.7, 4 x 10 mm, guard. This HPLC guard column has a densely packed weak cation exchange layer designed for monoclonal antibody separations. The particles are nonporous and promote higher resolution and faster separations. 763 
Add to Cart
  • Inner Diameter (ID)
  • 4 mm
  • Length
  • 10 mm
  • Phase
  • WCX
  • UNSPSC Code
  • 41115711
  • Brand
  • Agilent Bio MAb
  • Guard Column
  • Yes
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 80 °C
  • Part Number Application
  • Charge Variant Analysis PeptidesProteinsmAbs
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 1.7 µm
  • Particle Type
  • Non-porous
  • pH Range
  • 2-12
  • Pressure Rating
  • 689 bar
  • Separation Mode
  • Ion Exchange (IEX)
  • Shipping Solvent
  • Phosphate Buffer
  • Technique
  • LC
AGIL5190-2403 Agilent Bio MAb, NP3, 4.5 x 50 mm. This HPLC column has a densely packed weak cation exchange layer designed for monoclonal antibody separations. The particles are nonporous and promote higher resolution and faster separations. 1383 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 50 mm
  • Phase
  • WCX
  • UNSPSC Code
  • 41115711
  • Brand
  • Agilent Bio MAb
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 80 °C
  • Part Number Application
  • Charge Variant Analysis PeptidesProteinsmAbs
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 3 µm
  • Particle Type
  • Non-porous
  • pH Range
  • 2-12
  • Pressure Rating
  • 551 bar
  • Separation Mode
  • Ion Exchange (IEX)
  • Shipping Solvent
  • Phosphate Buffer
  • Technique
  • LC

Overview

The small molecule column portfolio includes state-of-the-art superficially porous InfinityLab Poroshell 120 columns as well as traditional fully porous ZORBAX, Polaris, and Pursuit columns.

When you choose Agilent small molecule LC columns, you get more than just a dependable product. You also get unmatched technical support from the world’s largest chromatography supplier.


Agilent gel permeation chromatography (GPC) and size exclusion chromatography (SEC) columns and standards have been the top-selling in the polymer industry for over 40 years. GPC and SEC is used to determine the molecular weight and size distribution of macromolecules. SEC and GPC columns generate accurate, reliable data for critical polymer parameters, including dispersity (PDI), molecular weight mass average (Mw), number average (Mn), and z-average (Mz).


The importance of understanding the attributes of a biologic drug, and the processes used to create it, cannot be underestimated.  Agilent AdvanceBio LC columns are designed and produced to provide results you can be sure of when analyzing highly complex biotherapeutic molecules and monitoring their purity, potency, and other critical quality attributes.



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