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Agilent offers the largest, most modern liquid chromatography (LC) column portfolios for small molecule analysis, with columns suitable for nearly all separation modes and applications.


Whether you are performing conventional or ultra-fast chromatography, separating biomolecules, or analyzing complex compounds, the industry’s highest-performing compounds deliver fast, reproducible results – all engineered with unparalleled quality and reliability.

Catalog No. Product Net Price
SUA0830103E3LS SUPREMA Lux, 3000Å, 8 x 300 mm, 10 µm. GPC/SEC column, molecular weight range 1000 to 3x10^6, ships in water, pre-equilibrated for use with light scattering detectors 2108 
Add to Cart
  • Inner Diameter (ID)
  • 8 mm
  • Length
  • 300 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • SUPREMA
  • Guard Column
  • No
  • Maximum Temperature
  • 80 °C
  • Molecular Weight Lower Limit
  • 1000 Da
  • Particle Size
  • 10 µm
  • Particle Type
  • Individual Pore Size
  • pH Range
  • 2-12
  • Pore Size
  • 3000 µm
  • Pressure Rating
  • 80 bar
  • Shipping Solvent
  • Water
EASYVALIDA-02 EasyValid replacement column for aqueous applications, 8 x 300 mm. GPC/SEC column, reference materials (part number PSS-DXTVAL) and user documentation (included with kit PSS-DXTKITVAL) required for use, ships in water 2180 
Add to Cart
  • Inner Diameter (ID)
  • 8 mm
  • Length
  • 300 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • EasyValid Aqueous
  • Guard Column
  • No
  • Maximum Temperature
  • 70 °C
  • pH Range
  • 2-8
  • Pressure Rating
  • 100 bar
  • Shipping Solvent
  • Water
PL2080-0700 Aqueous SEC start-up kit. Includes PL aquagel-OH MIXED-H 8 µm, 7.5 x 300 mm SEC column (p/n PL1149-6800), 9 EasiVial PEG/PEO 2 mL vials (3 x red,yellow,green), 3 Broad Dextran standard vials, with certifications and literature. 2785 
Add to Cart
  • Inner Diameter (ID)
  • 7.5 mm
  • Length
  • 300 mm
  • UNSPSC Code
  • 41115711
  • Guard Column
  • No
  • Maximum Temperature
  • 90 °C
  • Molecular Weight Lower Limit
  • 6000 Da
  • Particle Size
  • 8 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-10
  • Pressure Rating
  • 150 bar
  • Shipping Solvent
  • 0.02% Sodium azide
AGIL5069-3635 Bio-Monolith QA, 4.95 x 5.2 mm. Polymer-based, monolith HPLC columns designed for macro bio-molecule separations. Bio-Monolith QA is a strong anion exchange column. 1369 
Add to Cart
  • Inner Diameter (ID)
  • 5.2 mm
  • Length
  • 5 mm
  • Phase
  • SAX
  • UNSPSC Code
  • 41115711
  • Brand
  • Bio-Monolith
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 40 °C
  • Part Number Application
  • Monoclonal Antibodies (mABs) Proteins
  • Part Number Application Domain
  • Biopharma
  • Particle Type
  • Monolith
  • pH Range
  • 2-11
  • Pressure Rating
  • 150 bar
  • Separation Mode
  • Ion Exchange (IEX)
  • Shipping Solvent
  • 20% Ethanol
  • Technique
  • LC
AGIL5069-3636 Bio-Monolith DEAE, 4.95 x 5.2 mm. Polymer-based, monolith HPLC columns designed for macro bio-molecule separations. Bio-Monolith DEAE is a weak anion exchange column. 1369 
Add to Cart
  • Inner Diameter (ID)
  • 5.2 mm
  • Length
  • 5 mm
  • Phase
  • DEAE
  • UNSPSC Code
  • 41115711
  • Brand
  • Bio-Monolith
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 40 °C
  • Part Number Application
  • Monoclonal Antibodies (mABs) OligosProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Type
  • Monolith
  • pH Range
  • 2-11
  • Pressure Rating
  • 150 bar
  • Separation Mode
  • Ion Exchange (IEX)
  • Shipping Solvent
  • 20% Ethanol
  • Technique
  • LC
AGIL5069-3637 Bio-Monolith SO3, 4.95 x 5.2 mm. Polymer-based, monolith HPLC columns designed for macro bio-molecule separations. Bio-Monolith SO3 is a strong cation exchange column. 1369 
Add to Cart
  • Inner Diameter (ID)
  • 5.2 mm
  • Length
  • 5 mm
  • Phase
  • SCX
  • UNSPSC Code
  • 41115711
  • Brand
  • Bio-Monolith
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 40 °C
  • Part Number Application
  • Monoclonal Antibodies (mABs) Proteins
  • Part Number Application Domain
  • Biopharma
  • Particle Type
  • Monolith
  • pH Range
  • 2-11
  • Pressure Rating
  • 150 bar
  • Separation Mode
  • Ion Exchange (IEX)
  • Shipping Solvent
  • 20% Ethanol
  • Technique
  • LC
AGIL5069-3639 Bio-Monolith Protein A, 4.95 x 5.2 mm. Store columns at 4-8 °C before and after use, extra delivery cost for cold shipment. 1595 
Add to Cart
  • Inner Diameter (ID)
  • 5.2 mm
  • Length
  • 5 mm
  • Phase
  • Protein A
  • UNSPSC Code
  • 41115711
  • Brand
  • Bio-Monolith
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 40 °C
  • Part Number Application
  • Antibody Titer Determination
  • Part Number Application Domain
  • Biopharma
  • Particle Type
  • Monolith
  • pH Range
  • 2-11
  • Pressure Rating
  • 150 bar
  • Separation Mode
  • Affinity
  • Shipping Solvent
  • 20mM Tris + 20% Ethanol
  • Technique
  • LC
AGIL5190-6900 Bio-Monolith Protein G, 4.95 x 5.2 mm, LC column. Store columns at 4-8 °C before and after use, extra delivery cost for cold shipment. 1556 
Add to Cart
  • Inner Diameter (ID)
  • 5.2 mm
  • Length
  • 5 mm
  • Phase
  • Protein G
  • UNSPSC Code
  • 41115711
  • Brand
  • Bio-Monolith Protein G
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 40 °C
  • Part Number Application
  • Antibody Titer Determination
  • Part Number Application Domain
  • Biopharma
  • Particle Type
  • Monolith
  • pH Range
  • 2-11
  • Pressure Rating
  • 150 bar
  • Separation Mode
  • Affinity
  • Shipping Solvent
  • 20mM Tris + 20% Ethanol
  • Technique
  • LC
AGIL5190-6903 Bio-Monolith Recombinant Protein A, 4.95 x 5.2 mm 1217 
Add to Cart
  • Inner Diameter (ID)
  • 5.2 mm
  • Length
  • 5 mm
  • Phase
  • Protein A
  • Brand
  • Bio-Monolith Protein A
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 40 °C
  • Particle Type
  • Monolith
  • pH Range
  • 2-11
  • Pressure Rating
  • 150 bar
  • Separation Mode
  • Affinity
  • Shipping Solvent
  • 20mM Tris + 20% Ethanol
  • Technique
  • LC
AGIL5064-8255 ZORBAX StableBond C18, 0.3 x 150 mm, 5 µm 633 
Add to Cart
  • Inner Diameter (ID)
  • 0.3 mm
  • Length
  • 150 mm
  • Phase
  • SB-C18
  • UNSPSC Code
  • 41115709
  • USP Designation
  • L1
  • Brand
  • ZORBAX
  • Carbon Load
  • 10 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • SS, Glass Lined
  • LC Platform
  • Capillary/Nano
  • Maximum Temperature
  • 40 °C at pH 6-8 90 °C at pH 1-6 40 °C at pH 6-890 °C at pH 1-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 0.8-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water

Overview

The small molecule column portfolio includes state-of-the-art superficially porous InfinityLab Poroshell 120 columns as well as traditional fully porous ZORBAX, Polaris, and Pursuit columns.

When you choose Agilent small molecule LC columns, you get more than just a dependable product. You also get unmatched technical support from the world’s largest chromatography supplier.


Agilent gel permeation chromatography (GPC) and size exclusion chromatography (SEC) columns and standards have been the top-selling in the polymer industry for over 40 years. GPC and SEC is used to determine the molecular weight and size distribution of macromolecules. SEC and GPC columns generate accurate, reliable data for critical polymer parameters, including dispersity (PDI), molecular weight mass average (Mw), number average (Mn), and z-average (Mz).


The importance of understanding the attributes of a biologic drug, and the processes used to create it, cannot be underestimated.  Agilent AdvanceBio LC columns are designed and produced to provide results you can be sure of when analyzing highly complex biotherapeutic molecules and monitoring their purity, potency, and other critical quality attributes.



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