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Agilent offers the largest, most modern liquid chromatography (LC) column portfolios for small molecule analysis, with columns suitable for nearly all separation modes and applications.


Whether you are performing conventional or ultra-fast chromatography, separating biomolecules, or analyzing complex compounds, the industry’s highest-performing compounds deliver fast, reproducible results – all engineered with unparalleled quality and reliability.

Catalog No. Product Net Price
AGIL880952-205 ZORBAX Original 70Å CN, 5 µm, 9.4 x 250 mm 1601 
Add to Cart
  • Inner Diameter (ID)
  • 9.4 mm
  • Length
  • 250 mm
  • Phase
  • Original CN
  • UNSPSC Code
  • 41115709
  • Brand
  • ZORBAX
  • Carbon Load
  • 7 %
  • Endcapped
  • Yes
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 60 °C
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-7
  • Pore Size
  • 70 Å
  • Pressure Rating
  • 340 bar
  • Separation Mode
  • Normal Phase
AGIL880952-206 ZORBAX Original 70Å C8, 9.4 x 250 mm, 5 µm HPLC column 1601 
Add to Cart
  • Inner Diameter (ID)
  • 9.4 mm
  • Length
  • 250 mm
  • Phase
  • Original C8
  • UNSPSC Code
  • 41115709
  • Brand
  • ZORBAX
  • Carbon Load
  • 12 %
  • Endcapped
  • Yes
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 60 °C
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-8
  • Pore Size
  • 70 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
AGIL880967-201 ZORBAX Rx 80Å C8, 9.4 x 250 mm, 5 µm. 80Å 1659 
Add to Cart
  • Inner Diameter (ID)
  • 9.4 mm
  • Length
  • 250 mm
  • Phase
  • Rx-C8
  • UNSPSC Code
  • 41115709
  • Brand
  • ZORBAX
  • Carbon Load
  • 5.5 %
  • Endcapped
  • No
  • Guard Column
  • Yes
  • Hardware
  • Conventional
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 40 °C at pH 6-8 80 °C at pH 1-6 40 °C at pH 6-880 °C at pH 1-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 340 bar
  • Separation Mode
  • Reversed Phase
AGIL880975-205 ZORBAX StableBond CN, 9.4 x 250 mm, 5 µm. 80Å 1625 
Add to Cart
  • Inner Diameter (ID)
  • 9.4 mm
  • Length
  • 250 mm
  • Phase
  • SB-CN
  • UNSPSC Code
  • 41115709
  • USP Designation
  • L10
  • Brand
  • ZORBAX
  • Carbon Load
  • 4 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 40 °C at pH 6-8 80 °C at pH 1-6 40 °C at pH 6-880 °C at pH 1-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 350 bar
  • Separation Mode
  • Reversed Phase
AGIL880975-209 ZORBAX StableBond C3, 9.4 x 250 mm, 5 µm. 80Å 1625 
Add to Cart
  • Inner Diameter (ID)
  • 9.4 mm
  • Length
  • 250 mm
  • Phase
  • SB-C3
  • UNSPSC Code
  • 41115709
  • USP Designation
  • L56
  • Brand
  • ZORBAX
  • Carbon Load
  • 4 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 40 °C at pH 6-8 80 °C at pH 1-6 40 °C at pH 6-880 °C at pH 1-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 350 bar
  • Separation Mode
  • Reversed Phase
AGIL880975-212 ZORBAX StableBond Phenyl, 9.4 x 250 mm, 5 µm. 80Å 1625 
Add to Cart
  • Inner Diameter (ID)
  • 9.4 mm
  • Length
  • 250 mm
  • Phase
  • SB-Phenyl
  • UNSPSC Code
  • 41115711
  • Brand
  • ZORBAX
  • Carbon Load
  • 5.5 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 40 °C at pH 6-8 80 °C at pH 1-6 40 °C at pH 6-880 °C at pH 1-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 350 bar
  • Separation Mode
  • Reversed Phase
AGIL880995-206 ZORBAX StableBond 300 C8, 9.4 x 250 mm, 5 µm. A reversed-phase C8 semi-prep HPLC column with fully porous ZORBAX particles. StableBond technology ensures stability at low pH. 1591 
Add to Cart
  • Inner Diameter (ID)
  • 9.4 mm
  • Length
  • 250 mm
  • Phase
  • 300SB-C8
  • UNSPSC Code
  • 41115709
  • Brand
  • ZORBAX 300SB-C8
  • Hardware
  • SS
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 80 °C
  • Part Number Application
  • Monoclonal Antibodies (mABs) PeptidesProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-8
  • Pore Size
  • 300 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC LC & LC/MS
AGIL880995-206 ZORBAX StableBond 300 C8, 9.4 x 250 mm, 5 µm. A reversed-phase C8 semi-prep HPLC column with fully porous ZORBAX particles. StableBond technology ensures stability at low pH. 1591 
Add to Cart
  • Inner Diameter (ID)
  • 9.4 mm
  • Length
  • 250 mm
  • Phase
  • 300SB-C8
  • UNSPSC Code
  • 41115709
  • Brand
  • ZORBAX 300SB-C8
  • Hardware
  • SS
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 80 °C
  • Part Number Application
  • Monoclonal Antibodies (mABs) PeptidesProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-8
  • Pore Size
  • 300 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC LC & LC/MS
AGIL884973-901 ZORBAX GF-250, 9.4 x 250 mm, 4 µm 2003 
Add to Cart
  • Inner Diameter (ID)
  • 9.4 mm
  • Length
  • 250 mm
  • Phase
  • GF-250
  • UNSPSC Code
  • 41115711
  • Brand
  • ZORBAX
  • Hardware
  • SS
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 60 °C
  • Molecular Weight Lower Limit
  • 4000 Da
  • Part Number Application
  • Aggregate & Fragment Analysis PeptidesProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 4 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 3-8.5
  • Pore Size
  • 150 Å
  • Separation Mode
  • Size Exclusion (SEC)
  • Shipping Solvent
  • Phosphate Buffer
  • Technique
  • LC
AGIL884973-902 ZORBAX GF-450, 9.4 x 250 mm, 6 µm 2003 
Add to Cart
  • Inner Diameter (ID)
  • 9.4 mm
  • Length
  • 250 mm
  • Phase
  • GF-450
  • UNSPSC Code
  • 41115711
  • Brand
  • ZORBAX
  • Hardware
  • SS
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 60 °C
  • Molecular Weight Lower Limit
  • 10000 Da
  • Part Number Application
  • Aggregate & Fragment Analysis PeptidesProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 6 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 3-8.5
  • Pore Size
  • 300 Å
  • Separation Mode
  • Size Exclusion (SEC)
  • Shipping Solvent
  • Phosphate Buffer
  • Technique
  • LC

Overview

The small molecule column portfolio includes state-of-the-art superficially porous InfinityLab Poroshell 120 columns as well as traditional fully porous ZORBAX, Polaris, and Pursuit columns.

When you choose Agilent small molecule LC columns, you get more than just a dependable product. You also get unmatched technical support from the world’s largest chromatography supplier.


Agilent gel permeation chromatography (GPC) and size exclusion chromatography (SEC) columns and standards have been the top-selling in the polymer industry for over 40 years. GPC and SEC is used to determine the molecular weight and size distribution of macromolecules. SEC and GPC columns generate accurate, reliable data for critical polymer parameters, including dispersity (PDI), molecular weight mass average (Mw), number average (Mn), and z-average (Mz).


The importance of understanding the attributes of a biologic drug, and the processes used to create it, cannot be underestimated.  Agilent AdvanceBio LC columns are designed and produced to provide results you can be sure of when analyzing highly complex biotherapeutic molecules and monitoring their purity, potency, and other critical quality attributes.



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