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Agilent offers the largest, most modern liquid chromatography (LC) column portfolios for small molecule analysis, with columns suitable for nearly all separation modes and applications.


Whether you are performing conventional or ultra-fast chromatography, separating biomolecules, or analyzing complex compounds, the industry’s highest-performing compounds deliver fast, reproducible results – all engineered with unparalleled quality and reliability.

Catalog No. Product Net Price
AGIL410910-302 Agilent Prep 100Å C18, 30 x 250 mm, 10 µm 5561 
Add to Cart
  • Inner Diameter (ID)
  • 30 mm
  • Length
  • 250 mm
  • Phase
  • C18
  • UNSPSC Code
  • 41115711
  • Brand
  • Agilent Prep
  • Carbon Load
  • 24 %
  • Endcapped
  • Yes
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 40 °C at pH 8-9 60 °C at pH 2-8 40 °C at pH 8-1060 °C at pH 2-8
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 10 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-10
  • Pore Size
  • 100 Å
  • Pressure Rating
  • 340 bar
  • Separation Mode
  • Reversed Phase
AGIL410910-502 Agilent Prep 100Å C18, 50 x 250 mm, 10 µm 12094 
Add to Cart
  • Inner Diameter (ID)
  • 50 mm
  • Length
  • 250 mm
  • Phase
  • C18
  • UNSPSC Code
  • 41115711
  • Brand
  • Agilent Prep
  • Carbon Load
  • 24 %
  • Endcapped
  • Yes
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 40 °C at pH 8-9 60 °C at pH 2-8 40 °C at pH 8-1060 °C at pH 2-8
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 10 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-10
  • Pore Size
  • 100 Å
  • Pressure Rating
  • 200 bar
  • Separation Mode
  • Reversed Phase
AGIL413910-302 Agilent Prep 100Å C18, 30 x 150 mm, 10 µm 3956 
Add to Cart
  • Inner Diameter (ID)
  • 30 mm
  • Length
  • 150 mm
  • Phase
  • C18
  • UNSPSC Code
  • 41115711
  • Brand
  • Agilent Prep
  • Carbon Load
  • 24 %
  • Endcapped
  • Yes
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 40 °C at pH 8-9 60 °C at pH 2-8 40 °C at pH 8-1060 °C at pH 2-8
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 10 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-10
  • Pore Size
  • 100 Å
  • Pressure Rating
  • 340 bar
  • Separation Mode
  • Reversed Phase
AGIL413910-502 Agilent Prep 100Å C18, 50 x 150 mm, 10 µm 7563 
Add to Cart
  • Inner Diameter (ID)
  • 50 mm
  • Length
  • 150 mm
  • Phase
  • C18
  • UNSPSC Code
  • 41115711
  • Brand
  • Agilent Prep
  • Carbon Load
  • 24 %
  • Endcapped
  • Yes
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 40 °C at pH 8-9 60 °C at pH 2-8 40 °C at pH 8-1060 °C at pH 2-8
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 10 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-10
  • Pore Size
  • 100 Å
  • Pressure Rating
  • 200 bar
  • Separation Mode
  • Reversed Phase
AGIL419910-302 Agilent Prep 100Å C18, 30 x 100 mm, 10 µm 2842 
Add to Cart
  • Inner Diameter (ID)
  • 30 mm
  • Length
  • 100 mm
  • Phase
  • C18
  • UNSPSC Code
  • 41115711
  • Brand
  • Agilent Prep
  • Carbon Load
  • 24 %
  • Endcapped
  • Yes
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 40 °C at pH 8-9 60 °C at pH 2-8 40 °C at pH 8-1060 °C at pH 2-8
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 10 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-10
  • Pore Size
  • 100 Å
  • Pressure Rating
  • 340 bar
  • Separation Mode
  • Reversed Phase
AGIL419910-502 Agilent Prep 100Å C18, 50 x 100 mm, 10 µm 5421 
Add to Cart
  • Inner Diameter (ID)
  • 50 mm
  • Length
  • 100 mm
  • Phase
  • C18
  • UNSPSC Code
  • 41115711
  • Brand
  • Agilent Prep
  • Carbon Load
  • 24 %
  • Endcapped
  • Yes
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 40 °C at pH 8-9 60 °C at pH 2-8 40 °C at pH 8-1060 °C at pH 2-8
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 10 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-10
  • Pore Size
  • 100 Å
  • Pressure Rating
  • 200 bar
  • Separation Mode
  • Reversed Phase
AGIL440905-902 Agilent Prep-C18 Scalar column, 100Å, 4.6 x 250 mm, 5 µm, 400 bar pressure limit 519 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 250 mm
  • Phase
  • Prep-C18
  • UNSPSC Code
  • 41115711
  • Brand
  • Agilent Prep
  • Carbon Load
  • 24 %
  • Endcapped
  • Yes
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 40 °C at pH 8-9 60 °C at pH 2-8 40 °C at pH 8-1060 °C at pH 2-8
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-10
  • Pore Size
  • 100 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Methanol
AGIL440910-902 Agilent Prep-C18 Scalar column, 100Å, 4.6 x 250 mm, 10 µm, 400 bar pressure limit 519 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 250 mm
  • Phase
  • Prep-C18
  • UNSPSC Code
  • 41115711
  • Brand
  • Agilent Prep
  • Carbon Load
  • 24 %
  • Endcapped
  • Yes
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 40 °C at pH 8-9 60 °C at pH 2-8 40 °C at pH 8-1060 °C at pH 2-8
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 10 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-10
  • Pore Size
  • 100 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Methanol
AGIL443905-902 Agilent Prep-C18 Scalar column, 100Å, 4.6 x 150 mm, 5 µm, 400 bar pressure limit 469 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 150 mm
  • Phase
  • Prep-C18
  • UNSPSC Code
  • 41115711
  • Brand
  • Agilent Prep
  • Carbon Load
  • 24 %
  • Endcapped
  • Yes
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 40 °C at pH 8-9 60 °C at pH 2-8 40 °C at pH 8-1060 °C at pH 2-8
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-10
  • Pore Size
  • 100 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Methanol
AGIL443910-902 Agilent Prep-C18 Scalar column, 100Å, 4.6 x 150 mm, 10 µm, 400 bar pressure limit 469 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 150 mm
  • Phase
  • Prep-C18
  • UNSPSC Code
  • 41115711
  • Brand
  • Agilent Prep
  • Carbon Load
  • 24 %
  • Endcapped
  • Yes
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 40 °C at pH 8-9 60 °C at pH 2-8 40 °C at pH 8-1060 °C at pH 2-8
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 10 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-10
  • Pore Size
  • 100 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Methanol

Overview

The small molecule column portfolio includes state-of-the-art superficially porous InfinityLab Poroshell 120 columns as well as traditional fully porous ZORBAX, Polaris, and Pursuit columns.

When you choose Agilent small molecule LC columns, you get more than just a dependable product. You also get unmatched technical support from the world’s largest chromatography supplier.


Agilent gel permeation chromatography (GPC) and size exclusion chromatography (SEC) columns and standards have been the top-selling in the polymer industry for over 40 years. GPC and SEC is used to determine the molecular weight and size distribution of macromolecules. SEC and GPC columns generate accurate, reliable data for critical polymer parameters, including dispersity (PDI), molecular weight mass average (Mw), number average (Mn), and z-average (Mz).


The importance of understanding the attributes of a biologic drug, and the processes used to create it, cannot be underestimated.  Agilent AdvanceBio LC columns are designed and produced to provide results you can be sure of when analyzing highly complex biotherapeutic molecules and monitoring their purity, potency, and other critical quality attributes.



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