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Agilent offers the largest, most modern liquid chromatography (LC) column portfolios for small molecule analysis, with columns suitable for nearly all separation modes and applications.


Whether you are performing conventional or ultra-fast chromatography, separating biomolecules, or analyzing complex compounds, the industry’s highest-performing compounds deliver fast, reproducible results – all engineered with unparalleled quality and reliability.

Catalog No. Product Net Price
AGIL963954-302 ZORBAX RR Eclipse XDB-C18, 80Å, 3.0 x 150 mm, 3.5 µm 725 
Add to Cart
  • Inner Diameter (ID)
  • 3 mm
  • Length
  • 150 mm
  • Phase
  • Eclipse XDB-C18
  • UNSPSC Code
  • 41115709
  • USP Designation
  • L1
  • Brand
  • ZORBAX
  • Carbon Load
  • 10 %
  • Endcapped
  • Double
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC
  • Maximum Temperature
  • 40 °C at pH 6-9 60 °C at pH 2-6 40 °C at pH 6-960 °C at pH 2-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 3.5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-9
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Methanol/Water
AGIL963954-305 ZORBAX RR Eclipse XDB-CN, 80Å, 3.0 x 150 mm, 3.5 µm 725 
Add to Cart
  • Inner Diameter (ID)
  • 3 mm
  • Length
  • 150 mm
  • Phase
  • Eclipse XDB-CN
  • UNSPSC Code
  • 41115709
  • USP Designation
  • L10
  • Brand
  • ZORBAX
  • Carbon Load
  • 4.3 %
  • Endcapped
  • Double
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC
  • Maximum Temperature
  • 40 °C at pH 6-9 60 °C at pH 2-6 40 °C at pH 6-960 °C at pH 2-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 3.5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-9
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
AGIL990967-302 ZORBAX Eclipse XDB-C18, 80Å, 3.0 x 250 mm, 5 µm, 400 bar pressure limit 706 
Add to Cart
  • Inner Diameter (ID)
  • 3 mm
  • Length
  • 250 mm
  • Phase
  • Eclipse XDB-C18
  • UNSPSC Code
  • 41115709
  • USP Designation
  • L1
  • Brand
  • ZORBAX
  • Carbon Load
  • 10 %
  • Endcapped
  • Double
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC
  • Maximum Temperature
  • 40 °C at pH 6-9 60 °C at pH 2-6 40 °C at pH 6-960 °C at pH 2-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-9
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Methanol/Water
AGIL990967-312 ZORBAX Eclipse XDB-Phenyl, 80Å, 3.0 x 250 mm,5 µm, 400 bar pressure limit 706 
Add to Cart
  • Inner Diameter (ID)
  • 3 mm
  • Length
  • 250 mm
  • Phase
  • Eclipse XDB-Phenyl
  • UNSPSC Code
  • 41115711
  • USP Designation
  • L11
  • Brand
  • ZORBAX
  • Carbon Load
  • 7.2 %
  • Endcapped
  • Double
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC
  • Maximum Temperature
  • 40 °C at pH 6-9 60 °C at pH 2-6 40 °C at pH 6-960 °C at pH 2-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-9
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Methanol/Water
AGIL993967-306 ZORBAX Eclipse XDB-C8, 80Å, 3.0 x 150 mm, 5 µm, 400 bar pressure limit 644 
Add to Cart
  • Inner Diameter (ID)
  • 3 mm
  • Length
  • 150 mm
  • Phase
  • Eclipse XDB-C8
  • UNSPSC Code
  • 41115709
  • USP Designation
  • L7
  • Brand
  • ZORBAX
  • Carbon Load
  • 7.6 %
  • Endcapped
  • Double
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC
  • Maximum Temperature
  • 40 °C at pH 6-9 60 °C at pH 2-6 40 °C at pH 6-960 °C at pH 2-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-9
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Methanol/Water
AGIL993967-312 ZORBAX Eclipse XDB-Phenyl, 80Å, 3.0 x 150 mm, 5 µm, 400 bar pressure limit 644 
Add to Cart
  • Inner Diameter (ID)
  • 3 mm
  • Length
  • 150 mm
  • Phase
  • Eclipse XDB-Phenyl
  • UNSPSC Code
  • 41115711
  • USP Designation
  • L11
  • Brand
  • ZORBAX
  • Carbon Load
  • 7.2 %
  • Endcapped
  • Double
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC
  • Maximum Temperature
  • 40 °C at pH 6-9 60 °C at pH 2-6 40 °C at pH 6-960 °C at pH 2-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-9
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Methanol/Water
AGIL5188-5202 Spin Concentrators, 50K MWCO, 4 mL capacity 25/pk 196 
Add to Cart
  • UNSPSC Code
  • 41104800
SUA080505 SUPREMA, 8 x 50 mm, 5 µm. GPC/SEC guard column, ships in water 591 
Add to Cart
  • Inner Diameter (ID)
  • 8 mm
  • Length
  • 50 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • SUPREMA
  • Guard Column
  • Yes
  • Maximum Temperature
  • 80 °C
  • Particle Size
  • 5 µm
  • pH Range
  • 2-12
  • Pressure Rating
  • 120 bar
  • Shipping Solvent
  • Water
SUA080510LS SUPREMA Lux, 8 x 50 mm, 10 µm. GPC/SEC guard column, ships in water, pre-equilibrated for use with light scattering detectors 672 
Add to Cart
  • Inner Diameter (ID)
  • 8 mm
  • Length
  • 50 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • SUPREMA
  • Guard Column
  • Yes
  • Maximum Temperature
  • 80 °C
  • Particle Size
  • 10 µm
  • pH Range
  • 2-12
  • Pressure Rating
  • 80 bar
  • Shipping Solvent
  • Water
SUA0830031E2 SUPREMA, 100Å, 8 x 300 mm, 3 µm. GPC/SEC column, molecular weight range 100 to 10^5, ships in water 2448 
Add to Cart
  • Inner Diameter (ID)
  • 8 mm
  • Length
  • 300 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • SUPREMA
  • Guard Column
  • No
  • Maximum Temperature
  • 80 °C
  • Molecular Weight Lower Limit
  • 100 Da
  • Particle Size
  • 3 µm
  • Particle Type
  • Individual Pore Size
  • pH Range
  • 2-12
  • Pore Size
  • 100 µm
  • Pressure Rating
  • 150 bar
  • Shipping Solvent
  • Water

Overview

The small molecule column portfolio includes state-of-the-art superficially porous InfinityLab Poroshell 120 columns as well as traditional fully porous ZORBAX, Polaris, and Pursuit columns.

When you choose Agilent small molecule LC columns, you get more than just a dependable product. You also get unmatched technical support from the world’s largest chromatography supplier.


Agilent gel permeation chromatography (GPC) and size exclusion chromatography (SEC) columns and standards have been the top-selling in the polymer industry for over 40 years. GPC and SEC is used to determine the molecular weight and size distribution of macromolecules. SEC and GPC columns generate accurate, reliable data for critical polymer parameters, including dispersity (PDI), molecular weight mass average (Mw), number average (Mn), and z-average (Mz).


The importance of understanding the attributes of a biologic drug, and the processes used to create it, cannot be underestimated.  Agilent AdvanceBio LC columns are designed and produced to provide results you can be sure of when analyzing highly complex biotherapeutic molecules and monitoring their purity, potency, and other critical quality attributes.



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