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Agilent offers the largest, most modern liquid chromatography (LC) column portfolios for small molecule analysis, with columns suitable for nearly all separation modes and applications.


Whether you are performing conventional or ultra-fast chromatography, separating biomolecules, or analyzing complex compounds, the industry’s highest-performing compounds deliver fast, reproducible results – all engineered with unparalleled quality and reliability.

Catalog No. Product Net Price
AGIL863668-301 ZORBAX RR Bonus-RP, 80Å, 3.0 x 150 mm, 3.5 µm, 600 bar pressure limit 716 
Add to Cart
  • Inner Diameter (ID)
  • 3 mm
  • Length
  • 150 mm
  • Phase
  • Bonus-RP
  • UNSPSC Code
  • 41115711
  • USP Designation
  • L60
  • Brand
  • ZORBAX
  • Carbon Load
  • 9.5 %
  • Endcapped
  • Triple
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC
  • Maximum Temperature
  • 40 °C at pH 8-9 60 °C at pH 2-8 40 °C at pH 8-960 °C at pH 2-8
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 3.5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-9
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 600 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Methanol/Water
AGIL863954-305 ZORBAX RR StableBond CN, 3.0 x 150 mm, 3.5 µm. 80Å 723 
Add to Cart
  • Inner Diameter (ID)
  • 3 mm
  • Length
  • 150 mm
  • Phase
  • SB-CN
  • UNSPSC Code
  • 41115709
  • USP Designation
  • L10
  • Brand
  • ZORBAX
  • Carbon Load
  • 4 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC
  • Maximum Temperature
  • 40 °C at pH 6-8 80 °C at pH 1-6 40 °C at pH 6-880 °C at pH 1-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 3.5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Normal Phase Reversed Phase SFC
  • Shipping Solvent
  • Acetonitrile/Water
AGIL863954-312 ZORBAX RR StableBondPhenyl, 3.0 x 150 mm, 3.5 µm. 80Å 723 
Add to Cart
  • Inner Diameter (ID)
  • 3 mm
  • Length
  • 150 mm
  • Phase
  • SB-Phenyl
  • UNSPSC Code
  • 41115711
  • Brand
  • ZORBAX
  • Carbon Load
  • 5.5 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC
  • Maximum Temperature
  • 40 °C at pH 6-8 80 °C at pH 1-6 40 °C at pH 6-880 °C at pH 1-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 3.5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
AGIL863967-302 ZORBAX RR Rx-C18, 80Å, 3.0 x 150 mm, 3.5 µm, 400 bar pressure limit 645 
Add to Cart
  • Inner Diameter (ID)
  • 3 mm
  • Length
  • 150 mm
  • Phase
  • Rx-C18
  • UNSPSC Code
  • 41115709
  • Brand
  • ZORBAX
  • Carbon Load
  • 12 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC
  • Maximum Temperature
  • 40 °C at pH 6-9 60 °C at pH 2-6 40 °C at pH 6-860 °C at pH 2-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 3.5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
AGIL863974-302 ZORBAX StableBond 300 C18, 3.0 x 150 mm, 3.5 µm. A reversed-phase C18 HPLC column with fully porous ZORBAX particles. StableBond technology ensures stability at low pH. 686 
Add to Cart
  • Inner Diameter (ID)
  • 3 mm
  • Length
  • 150 mm
  • Phase
  • 300SB-C18
  • UNSPSC Code
  • 41115709
  • Brand
  • ZORBAX 300SB-C18
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 90 °C
  • Part Number Application
  • Monoclonal Antibodies (mABs) PeptidesProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 3.5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-8
  • Pore Size
  • 300 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC LC & LC/MS
AGIL863974-302 ZORBAX StableBond 300 C18, 3.0 x 150 mm, 3.5 µm. A reversed-phase C18 HPLC column with fully porous ZORBAX particles. StableBond technology ensures stability at low pH. 686 
Add to Cart
  • Inner Diameter (ID)
  • 3 mm
  • Length
  • 150 mm
  • Phase
  • 300SB-C18
  • UNSPSC Code
  • 41115709
  • Brand
  • ZORBAX 300SB-C18
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 90 °C
  • Part Number Application
  • Monoclonal Antibodies (mABs) PeptidesProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 3.5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-8
  • Pore Size
  • 300 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC LC & LC/MS
AGIL863974-306 ZORBAX StableBond 300 C8, 3.0 x 150 mm, 3.5 µm. A reversed-phase C8 HPLC column with fully porous ZORBAX particles. StableBond technology ensures stability at low pH. 688 
Add to Cart
  • Inner Diameter (ID)
  • 3 mm
  • Length
  • 150 mm
  • Phase
  • 300SB-C8
  • UNSPSC Code
  • 41115709
  • Brand
  • ZORBAX 300SB-C8
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 80 °C
  • Part Number Application
  • Monoclonal Antibodies (mABs) PeptidesProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 3.5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-8
  • Pore Size
  • 300 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC LC & LC/MS
AGIL863974-309 ZORBAX StableBond 300 C3, 3.0 x 150 mm, 3.5 µm. A reversed-phase C3 HPLC column with fully porous ZORBAX particles. StableBond technology ensures stability at low pH. 686 
Add to Cart
  • Inner Diameter (ID)
  • 3 mm
  • Length
  • 150 mm
  • Phase
  • 300SB-C3
  • UNSPSC Code
  • 41115709
  • Brand
  • ZORBAX 300SB-C3
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 80 °C
  • Part Number Application
  • Monoclonal Antibodies (mABs) PeptidesProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 3.5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-8
  • Pore Size
  • 300 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC LC & LC/MS
AGIL880967-302 ZORBAX Rx-C18, 80Å, 3.0 x 250 mm, 5 µm, 400 bar pressure limit 706 
Add to Cart
  • Inner Diameter (ID)
  • 3 mm
  • Length
  • 250 mm
  • Phase
  • Rx-C18
  • UNSPSC Code
  • 41115709
  • Brand
  • ZORBAX
  • Carbon Load
  • 12 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC
  • Maximum Temperature
  • 40 °C at pH 6-9 60 °C at pH 2-6 40 °C at pH 6-860 °C at pH 2-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
AGIL880975-306 ZORBAX Rx-C8, 80Å, 3.0 x 250 mm, 5 µm, 400 bar pressure limit 706 
Add to Cart
  • Inner Diameter (ID)
  • 3 mm
  • Length
  • 250 mm
  • Phase
  • Rx-C8
  • UNSPSC Code
  • 41115709
  • Brand
  • ZORBAX
  • Carbon Load
  • 5.5 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC
  • Maximum Temperature
  • 40 °C at pH 6-8 80 °C at pH 1-6 40 °C at pH 6-880 °C at pH 1-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Methanol/Water

Overview

The small molecule column portfolio includes state-of-the-art superficially porous InfinityLab Poroshell 120 columns as well as traditional fully porous ZORBAX, Polaris, and Pursuit columns.

When you choose Agilent small molecule LC columns, you get more than just a dependable product. You also get unmatched technical support from the world’s largest chromatography supplier.


Agilent gel permeation chromatography (GPC) and size exclusion chromatography (SEC) columns and standards have been the top-selling in the polymer industry for over 40 years. GPC and SEC is used to determine the molecular weight and size distribution of macromolecules. SEC and GPC columns generate accurate, reliable data for critical polymer parameters, including dispersity (PDI), molecular weight mass average (Mw), number average (Mn), and z-average (Mz).


The importance of understanding the attributes of a biologic drug, and the processes used to create it, cannot be underestimated.  Agilent AdvanceBio LC columns are designed and produced to provide results you can be sure of when analyzing highly complex biotherapeutic molecules and monitoring their purity, potency, and other critical quality attributes.



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