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Agilent offers the largest, most modern liquid chromatography (LC) column portfolios for small molecule analysis, with columns suitable for nearly all separation modes and applications.


Whether you are performing conventional or ultra-fast chromatography, separating biomolecules, or analyzing complex compounds, the industry’s highest-performing compounds deliver fast, reproducible results – all engineered with unparalleled quality and reliability.

Catalog No. Product Net Price
SUP20301E3 SUPREMA, 1000Å, 20 x 300 mm, 10 µm. GPC/SEC column, molecular weight range 100 to 10^6, ships in water 4586 
Add to Cart
  • Inner Diameter (ID)
  • 20 mm
  • Length
  • 300 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • SUPREMA
  • Guard Column
  • No
  • Maximum Temperature
  • 80 °C
  • Molecular Weight Lower Limit
  • 100 Da
  • Particle Size
  • 10 µm
  • Particle Type
  • Individual Pore Size
  • pH Range
  • 2-12
  • Pore Size
  • 1000 µm
  • Pressure Rating
  • 80 bar
  • Shipping Solvent
  • Water
SUP20303E1 SUPREMA, 30Å, 20 x 300 mm, 10 µm. GPC/SEC column, molecular weight range 100 to 3x10^4, ships in water 4586 
Add to Cart
  • Inner Diameter (ID)
  • 20 mm
  • Length
  • 300 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • SUPREMA
  • Guard Column
  • No
  • Maximum Temperature
  • 80 °C
  • Molecular Weight Lower Limit
  • 100 Da
  • Particle Size
  • 10 µm
  • Particle Type
  • Individual Pore Size
  • pH Range
  • 2-12
  • Pore Size
  • 30 µm
  • Pressure Rating
  • 80 bar
  • Shipping Solvent
  • Water
SUP2030LIM SUPREMA, Linear-M, 20 x 300 mm, 10 µm. GPC/SEC column, molecular weight range 100 to 10^6, ships in water 5032 
Add to Cart
  • Inner Diameter (ID)
  • 20 mm
  • Length
  • 300 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • SUPREMA
  • Guard Column
  • No
  • Maximum Temperature
  • 80 °C
  • Molecular Weight Lower Limit
  • 100 Da
  • Particle Size
  • 10 µm
  • Particle Type
  • Mixed Pore Size
  • pH Range
  • 2-12
  • Pressure Rating
  • 80 bar
  • Shipping Solvent
  • Water
SUA0830101E2LS SUPREMA Lux, 100Å, 8 x 300 mm, 10 µm. GPC/SEC column, molecular weight range 100 to 10^5, ships in water, pre-equilibrated for use with light scattering detectors 2108 
Add to Cart
  • Inner Diameter (ID)
  • 8 mm
  • Length
  • 300 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • SUPREMA
  • Guard Column
  • No
  • Maximum Temperature
  • 80 °C
  • Molecular Weight Lower Limit
  • 100 Da
  • Particle Size
  • 10 µm
  • Particle Type
  • Individual Pore Size
  • pH Range
  • 2-12
  • Pore Size
  • 100 µm
  • Pressure Rating
  • 80 bar
  • Shipping Solvent
  • Water
PL1012-5A05 VariTide RPC, 10 x 250 mm, 6 µm 1113 
Add to Cart
  • Inner Diameter (ID)
  • 10 mm
  • Length
  • 250 mm
  • Phase
  • DVB
  • UNSPSC Code
  • 41115711
  • Brand
  • VariTide RPC
  • Hardware
  • SS
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 200 °C
  • Part Number Application
  • Peptides Proteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 6 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-14
  • Pore Size
  • 200 Å
  • Pressure Rating
  • 207 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC LC & LC/MS
PL1512-5A05 VariTide RPC, 4.6 x 250 mm, 6 µm 722 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 250 mm
  • Phase
  • DVB
  • UNSPSC Code
  • 41115711
  • Brand
  • VariTide RPC
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 200 °C
  • Part Number Application
  • Peptides Proteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 6 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-14
  • Pore Size
  • 200 Å
  • Pressure Rating
  • 207 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC LC & LC/MS
PL1E12-5A05 VariTide RPC, 21.2 x 250 mm, 6 µm 4406 
Add to Cart
  • Inner Diameter (ID)
  • 21.2 mm
  • Length
  • 250 mm
  • Phase
  • DVB
  • UNSPSC Code
  • 41115711
  • Brand
  • VariTide RPC
  • Hardware
  • SS
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 200 °C
  • Part Number Application
  • Peptides Proteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 6 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-14
  • Pore Size
  • 200 Å
  • Pressure Rating
  • 207 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC LC & LC/MS
AGIL5064-8253 ZORBAX StableBond C18, 0.3 x 35 mm, 5 µm, Cap/Nano guard, 1/pk 408 
Add to Cart
  • Inner Diameter (ID)
  • 0.3 mm
  • Length
  • 35 mm
  • Phase
  • SB-C18
  • UNSPSC Code
  • 41115711
  • USP Designation
  • L1
  • Brand
  • ZORBAX
  • Carbon Load
  • 10 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • SS, Glass Lined
  • LC Platform
  • Capillary/Nano
  • Maximum Temperature
  • 40 °C at pH 6-8 90 °C at pH 1-6 40 °C at pH 6-890 °C at pH 1-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 0.8-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
AGIL5064-8254 ZORBAX StableBond C18, 0.5 x 35 mm, 5 µm, Cap/Nano guard, 1/pk 408 
Add to Cart
  • Inner Diameter (ID)
  • 0.5 mm
  • Length
  • 35 mm
  • Phase
  • SB-C18
  • UNSPSC Code
  • 41115711
  • USP Designation
  • L1
  • Brand
  • ZORBAX
  • Carbon Load
  • 10 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • SS, Glass Lined
  • LC Platform
  • Capillary/Nano
  • Maximum Temperature
  • 40 °C at pH 6-8 90 °C at pH 1-6 40 °C at pH 6-890 °C at pH 1-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 0.8-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
AGIL5064-8256 ZORBAX StableBond C18, 0.5 x 150 mm, 5 µm 633 
Add to Cart
  • Inner Diameter (ID)
  • 0.5 mm
  • Length
  • 150 mm
  • Phase
  • SB-C18
  • UNSPSC Code
  • 41115709
  • USP Designation
  • L1
  • Brand
  • ZORBAX
  • Carbon Load
  • 10 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • SS, Glass Lined
  • LC Platform
  • Capillary/Nano
  • Maximum Temperature
  • 40 °C at pH 6-8 90 °C at pH 1-6 40 °C at pH 6-890 °C at pH 1-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 0.8-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water

Overview

The small molecule column portfolio includes state-of-the-art superficially porous InfinityLab Poroshell 120 columns as well as traditional fully porous ZORBAX, Polaris, and Pursuit columns.

When you choose Agilent small molecule LC columns, you get more than just a dependable product. You also get unmatched technical support from the world’s largest chromatography supplier.


Agilent gel permeation chromatography (GPC) and size exclusion chromatography (SEC) columns and standards have been the top-selling in the polymer industry for over 40 years. GPC and SEC is used to determine the molecular weight and size distribution of macromolecules. SEC and GPC columns generate accurate, reliable data for critical polymer parameters, including dispersity (PDI), molecular weight mass average (Mw), number average (Mn), and z-average (Mz).


The importance of understanding the attributes of a biologic drug, and the processes used to create it, cannot be underestimated.  Agilent AdvanceBio LC columns are designed and produced to provide results you can be sure of when analyzing highly complex biotherapeutic molecules and monitoring their purity, potency, and other critical quality attributes.



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