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Agilent offers the largest, most modern liquid chromatography (LC) column portfolios for small molecule analysis, with columns suitable for nearly all separation modes and applications.


Whether you are performing conventional or ultra-fast chromatography, separating biomolecules, or analyzing complex compounds, the industry’s highest-performing compounds deliver fast, reproducible results – all engineered with unparalleled quality and reliability.

Catalog No. Product Net Price
AGIL821075-918 Poroshell StableBond 300 C8, 2.1 x 12.5 mm, 5 µm, guard cartridge (ZGC) 4/pk. Use with hardware kit 820999-901. A 4-pack of reversed-phase C8 HPLC guard cartridges with superficially porous particles. StableBond technology ensures stability at low pH. 335 
Add to Cart
  • Inner Diameter (ID)
  • 2.1 mm
  • Length
  • 13 mm
  • Phase
  • 300SB-C8
  • UNSPSC Code
  • 41115711
  • Brand
  • Poroshell 300
  • Guard Column
  • Yes
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 90 °C
  • Part Number Application
  • Aggregate & Fragment AnalysisMonoclonal Antibodies (mABs)PeptidesProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 5 µm
  • Particle Type
  • Superficially Porous
  • pH Range
  • 1-8
  • Pore Size
  • 300 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Methanol/Water
  • Technique
  • LC
AGIL821075-920 Poroshell StableBond 300 C18, 2.1 x 12.5 mm, 5 µm, guard cartridge (ZGC) 4/pk. Use with hardware kit 820999-901. A 4-pack of reversed-phase C18 HPLC guard cartridges with superficially porous particles. StableBond technology ensures stability at low pH. 335 
Add to Cart
  • Inner Diameter (ID)
  • 2.1 mm
  • Length
  • 13 mm
  • Phase
  • 300SB-C18
  • UNSPSC Code
  • 41115711
  • Brand
  • Poroshell 300
  • Guard Column
  • Yes
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 90 °C
  • Part Number Application
  • Aggregate & Fragment AnalysisMonoclonal Antibodies (mABs)PeptidesProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 5 µm
  • Particle Type
  • Superficially Porous
  • pH Range
  • 1-8
  • Pore Size
  • 300 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Methanol/Water
  • Technique
  • LC
AGIL821075-924 Poroshell StableBond 300 C3, 2.1 x 12.5 mm, 5 µm, guard cartridge (ZGC) 4/pk. Use with hardware kit 820999-901. A 4-pack of reversed-phase C3 HPLC guard cartridges with superficially porous particles. StableBond technology ensures stability at low pH. 335 
Add to Cart
  • Inner Diameter (ID)
  • 2.1 mm
  • Length
  • 13 mm
  • Phase
  • 300SB-C3
  • UNSPSC Code
  • 41115711
  • Brand
  • Poroshell 300
  • Guard Column
  • Yes
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 90 °C
  • Part Number Application
  • Aggregate & Fragment AnalysisMonoclonal Antibodies (mABs)PeptidesProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 5 µm
  • Particle Type
  • Superficially Porous
  • pH Range
  • 1-8
  • Pore Size
  • 300 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Methanol/Water
  • Technique
  • LC
AGIL822600-909 Poroshell StableBond 300 C3, 1.0 x 30 mm, 5 µm. A reversed-phase C3 HPLC column with superficially porous particles. StableBond technology ensures stability at low pH. 942 
Add to Cart
  • Inner Diameter (ID)
  • 1 mm
  • Length
  • 30 mm
  • Phase
  • 300SB-C3
  • UNSPSC Code
  • 41115709
  • Brand
  • Poroshell 300
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 90 °C
  • Part Number Application
  • Aggregate & Fragment AnalysisMonoclonal Antibodies (mABs)PeptidesProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 5 µm
  • Particle Type
  • Superficially Porous
  • pH Range
  • 1-8
  • Pore Size
  • 300 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Methanol/Water
  • Technique
  • LC
PRA080505LS PROTEEMA Lux, 8 x 50 mm, 5 µm. GPC/SEC guard column, ships in water, pre-equilibrated for use with light scattering detectors 672 
Add to Cart
  • Inner Diameter (ID)
  • 8 mm
  • Length
  • 50 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • PROTEEMA
  • Guard Column
  • Yes
  • Maximum Temperature
  • 70 °C
  • Particle Size
  • 5 µm
  • pH Range
  • 2-8
  • Pressure Rating
  • 120 bar
  • Shipping Solvent
  • Water
PRA0830051E2LS PROTEEMA Lux, 100Å, 8 x 300 mm, 5 µm. GPC/SEC column, molecular weight range 100 to 1.5x10^5, ships in water, pre-equilibrated for use with light scattering detectors 2197 
Add to Cart
  • Inner Diameter (ID)
  • 8 mm
  • Length
  • 300 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • PROTEEMA
  • Guard Column
  • No
  • Maximum Temperature
  • 70 °C
  • Molecular Weight Lower Limit
  • 100 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Individual Pore Size
  • pH Range
  • 2-8
  • Pore Size
  • 100 µm
  • Pressure Rating
  • 120 bar
  • Shipping Solvent
  • Water
PRA0830051E3LS PROTEEMA Lux, 1000Å, 8 x 300 mm, 5 µm. GPC/SEC column, molecular weight range 1000 to 7.5x10^6, ships in water, pre-equilibrated for use with light scattering detectors 2197 
Add to Cart
  • Inner Diameter (ID)
  • 8 mm
  • Length
  • 300 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • PROTEEMA
  • Guard Column
  • No
  • Maximum Temperature
  • 70 °C
  • Molecular Weight Lower Limit
  • 1000 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Individual Pore Size
  • pH Range
  • 2-8
  • Pore Size
  • 1000 µm
  • Pressure Rating
  • 120 bar
  • Shipping Solvent
  • Water
PRA0830053E2LS PROTEEMA Lux, 300Å, 8 x 300 mm, 5 µm. GPC/SEC column, molecular weight range 1000 to 1.2x10^6, ships in water, pre-equilibrated for use with light scattering detectors 2197 
Add to Cart
  • Inner Diameter (ID)
  • 8 mm
  • Length
  • 300 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • PROTEEMA
  • Guard Column
  • No
  • Maximum Temperature
  • 70 °C
  • Molecular Weight Lower Limit
  • 1000 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Individual Pore Size
  • pH Range
  • 2-8
  • Pore Size
  • 300 µm
  • Pressure Rating
  • 120 bar
  • Shipping Solvent
  • Water
AGIL585050-906 InfinityLab ZORBAX SB-C8, 21.2 x 50 mm, 5 µm. Preparative LC column 1804 
Add to Cart
  • Inner Diameter (ID)
  • 21.2 mm
  • Length
  • 50 mm
  • Phase
  • SB-C8
  • Brand
  • ZORBAX
  • Carbon Load
  • 5.5 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 40 °C at pH 6-8 80 °C at pH 1-6 40 °C at pH 6-880 °C at pH 1-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
AGIL585150-906 InfinityLab ZORBAX SB-C8, 21.2 x 150 mm, 5 µm. Preparative LC column 3007 
Add to Cart
  • Inner Diameter (ID)
  • 21.2 mm
  • Length
  • 150 mm
  • Phase
  • SB-C8
  • Brand
  • ZORBAX
  • Carbon Load
  • 5.5 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 40 °C at pH 6-8 80 °C at pH 1-6 40 °C at pH 6-880 °C at pH 1-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water

Overview

The small molecule column portfolio includes state-of-the-art superficially porous InfinityLab Poroshell 120 columns as well as traditional fully porous ZORBAX, Polaris, and Pursuit columns.

When you choose Agilent small molecule LC columns, you get more than just a dependable product. You also get unmatched technical support from the world’s largest chromatography supplier.


Agilent gel permeation chromatography (GPC) and size exclusion chromatography (SEC) columns and standards have been the top-selling in the polymer industry for over 40 years. GPC and SEC is used to determine the molecular weight and size distribution of macromolecules. SEC and GPC columns generate accurate, reliable data for critical polymer parameters, including dispersity (PDI), molecular weight mass average (Mw), number average (Mn), and z-average (Mz).


The importance of understanding the attributes of a biologic drug, and the processes used to create it, cannot be underestimated.  Agilent AdvanceBio LC columns are designed and produced to provide results you can be sure of when analyzing highly complex biotherapeutic molecules and monitoring their purity, potency, and other critical quality attributes.



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