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Agilent offers the largest, most modern liquid chromatography (LC) column portfolios for small molecule analysis, with columns suitable for nearly all separation modes and applications.


Whether you are performing conventional or ultra-fast chromatography, separating biomolecules, or analyzing complex compounds, the industry’s highest-performing compounds deliver fast, reproducible results – all engineered with unparalleled quality and reliability.

Catalog No. Product Net Price
SDM052503LIM SDV, Linear-M, 4.6 x 250 mm, 3 µm. GPC/SEC column, molecular weight range 100 to 10^6, ships in THF 2516 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 250 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • SDV
  • Guard Column
  • No
  • Maximum Temperature
  • 100 °C
  • Molecular Weight Lower Limit
  • 100 Da
  • Particle Size
  • 3 µm
  • Particle Type
  • Mixed Pore Size
  • Pressure Rating
  • 150 bar
  • Shipping Solvent
  • THF
SDM052503LIS SDV, Linear-S, 4.6 x 250 mm, 3 µm. GPC/SEC column, molecular weight range 100 to 1.5x10^5, ships in THF 2516 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 250 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • SDV
  • Guard Column
  • No
  • Maximum Temperature
  • 100 °C
  • Molecular Weight Lower Limit
  • 100 Da
  • Particle Size
  • 3 µm
  • Particle Type
  • Mixed Pore Size
  • Pressure Rating
  • 150 bar
  • Shipping Solvent
  • THF
SDM052505LIM SDV, Linear-M, 4.6 x 250 mm, 5 µm. GPC/SEC column, molecular weight range 100 to 10^6, ships in THF 2189 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 250 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • SDV
  • Guard Column
  • No
  • Maximum Temperature
  • 100 °C
  • Molecular Weight Lower Limit
  • 100 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Mixed Pore Size
  • Pressure Rating
  • 100 bar
  • Shipping Solvent
  • THF
SDP20301E2 SDV, 100Å, 20 x 300 mm, 20 µm. GPC/SEC column, molecular weight range 100 to 10^4, ships in THF 4437 
Add to Cart
  • Inner Diameter (ID)
  • 20 mm
  • Length
  • 300 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • SDV
  • Guard Column
  • No
  • Maximum Temperature
  • 100 °C
  • Molecular Weight Lower Limit
  • 100 Da
  • Particle Size
  • 20 µm
  • Particle Type
  • Individual Pore Size
  • Pore Size
  • 100 µm
  • Pressure Rating
  • 60 bar
  • Shipping Solvent
  • THF
SDP20301E5 SDV, 10^5Å, 20 x 300 mm, 20 µm. GPC/SEC column, molecular weight range 1000 to 10^6, ships in THF 4437 
Add to Cart
  • Inner Diameter (ID)
  • 20 mm
  • Length
  • 300 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • SDV
  • Guard Column
  • No
  • Maximum Temperature
  • 100 °C
  • Molecular Weight Lower Limit
  • 1000 Da
  • Particle Size
  • 20 µm
  • Particle Type
  • Individual Pore Size
  • Pore Size
  • 100000 µm
  • Pressure Rating
  • 60 bar
  • Shipping Solvent
  • THF
SDP20301E6 SDV, 10^6Å, 20 x 300 mm, 20 µm. GPC/SEC column, molecular weight range 1000 to 3x10^6, ships in THF 4437 
Add to Cart
  • Inner Diameter (ID)
  • 20 mm
  • Length
  • 300 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • SDV
  • Guard Column
  • No
  • Maximum Temperature
  • 100 °C
  • Molecular Weight Lower Limit
  • 1000 Da
  • Particle Size
  • 20 µm
  • Particle Type
  • Individual Pore Size
  • Pore Size
  • 1000000 µm
  • Pressure Rating
  • 60 bar
  • Shipping Solvent
  • THF
SDP2030LIS SDV, Linear-S, 20 x 300 mm, 20 µm. GPC/SEC column, molecular weight range 100 to 1.5x10^5, ships in THF 4794 
Add to Cart
  • Inner Diameter (ID)
  • 20 mm
  • Length
  • 300 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • SDV
  • Guard Column
  • No
  • Maximum Temperature
  • 100 °C
  • Molecular Weight Lower Limit
  • 100 Da
  • Particle Size
  • 20 µm
  • Particle Type
  • Mixed Pore Size
  • Pressure Rating
  • 60 bar
  • Shipping Solvent
  • THF
SDS2005051E5 SDV, 10^5Å, 20 x 50 mm, 5 µm. GPC/SEC column, molecular weight range 1000 to 10^6, ships in THF 1743 
Add to Cart
  • Inner Diameter (ID)
  • 20 mm
  • Length
  • 50 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • SDV
  • Guard Column
  • No
  • Maximum Temperature
  • 100 °C
  • Molecular Weight Lower Limit
  • 1000 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Individual Pore Size
  • Pore Size
  • 100000 µm
  • Pressure Rating
  • 100 bar
  • Shipping Solvent
  • THF
AGIL763954-302 ZORBAX RR Extend-C18, 80Å, 3.0 x 150 mm, 3.5 µm 757 
Add to Cart
  • Inner Diameter (ID)
  • 3 mm
  • Length
  • 150 mm
  • Phase
  • Extend-C18
  • UNSPSC Code
  • 41115709
  • USP Designation
  • L1
  • Brand
  • ZORBAX
  • Carbon Load
  • 12.5 %
  • Endcapped
  • Double
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC
  • Maximum Temperature
  • 40 °C at pH 8-9 60 °C at pH 2-8 40 °C at pH 8-11.560 °C at pH 2-8
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 3.5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-11.5
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Methanol/Water
AGIL764953-302 ZORBAX RR Extend-C18, 80Å, 3.0 x 100 mm, 3.5 µm 693 
Add to Cart
  • Inner Diameter (ID)
  • 3 mm
  • Length
  • 100 mm
  • Phase
  • Extend-C18
  • UNSPSC Code
  • 41115709
  • USP Designation
  • L1
  • Brand
  • ZORBAX
  • Carbon Load
  • 12.5 %
  • Endcapped
  • Double
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC
  • Maximum Temperature
  • 40 °C at pH 8-9 60 °C at pH 2-8 40 °C at pH 8-11.560 °C at pH 2-8
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 3.5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-11.5
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Methanol/Water

Overview

The small molecule column portfolio includes state-of-the-art superficially porous InfinityLab Poroshell 120 columns as well as traditional fully porous ZORBAX, Polaris, and Pursuit columns.

When you choose Agilent small molecule LC columns, you get more than just a dependable product. You also get unmatched technical support from the world’s largest chromatography supplier.


Agilent gel permeation chromatography (GPC) and size exclusion chromatography (SEC) columns and standards have been the top-selling in the polymer industry for over 40 years. GPC and SEC is used to determine the molecular weight and size distribution of macromolecules. SEC and GPC columns generate accurate, reliable data for critical polymer parameters, including dispersity (PDI), molecular weight mass average (Mw), number average (Mn), and z-average (Mz).


The importance of understanding the attributes of a biologic drug, and the processes used to create it, cannot be underestimated.  Agilent AdvanceBio LC columns are designed and produced to provide results you can be sure of when analyzing highly complex biotherapeutic molecules and monitoring their purity, potency, and other critical quality attributes.



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