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Agilent offers the largest, most modern liquid chromatography (LC) column portfolios for small molecule analysis, with columns suitable for nearly all separation modes and applications.


Whether you are performing conventional or ultra-fast chromatography, separating biomolecules, or analyzing complex compounds, the industry’s highest-performing compounds deliver fast, reproducible results – all engineered with unparalleled quality and reliability.

Catalog No. Product Net Price
PL1570-5810 Hi-Plex Ca USP L19, 4.0 x 250 mm, 8 µm HPLC column 935 
Add to Cart
  • Inner Diameter (ID)
  • 4 mm
  • Length
  • 250 mm
  • Phase
  • Ca
  • UNSPSC Code
  • 41115711
  • USP Designation
  • L19
  • Brand
  • Hi-Plex
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Conventional
  • Maximum Temperature
  • 90 °C
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 8 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 7-7
  • Pressure Rating
  • 50 bar
  • Separation Mode
  • Ion Exclusion/Ligand Exchange
PL1570-6810 Hi-Plex Ca, 4.6 x 250 mm 1267 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 250 mm
  • Phase
  • Ca
  • UNSPSC Code
  • 41115711
  • USP Designation
  • L19
  • Brand
  • Hi-Plex
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Conventional
  • Maximum Temperature
  • 90 °C
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 8 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 7-7
  • Pressure Rating
  • 50 bar
  • Separation Mode
  • Ion Exclusion/Ligand Exchange
PL1570-6830 Hi-Plex H, 4.6 x 250 mm 1267 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 250 mm
  • Phase
  • H
  • UNSPSC Code
  • 41115711
  • USP Designation
  • L17L22
  • Brand
  • Hi-Plex
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Conventional
  • Maximum Temperature
  • 70 °C
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 8 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 0-7
  • Pressure Rating
  • 50 bar
  • Separation Mode
  • Ion Exclusion/Ligand Exchange
PL1670-0810 Hi-Plex Ca, 3.0 x 5.0 mm, 8 µm Guard cartridges, 2/pk 252 
Add to Cart
  • Inner Diameter (ID)
  • 3 mm
  • Length
  • 5 mm
  • Phase
  • Ca
  • UNSPSC Code
  • 41115711
  • USP Designation
  • L19
  • Brand
  • Hi-Plex
  • Endcapped
  • No
  • Guard Column
  • Yes
  • Hardware
  • Cartridge
  • Maximum Temperature
  • 90 °C
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 8 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 7-7
  • Pressure Rating
  • 50 bar
  • Separation Mode
  • Ion Exclusion/Ligand Exchange
PL1670-0820 Hi-Plex Pb, 3.0 x 5.0 mm, 8 µm Guard cartridges, 2/pk 252 
Add to Cart
  • Inner Diameter (ID)
  • 3 mm
  • Length
  • 5 mm
  • Phase
  • Pb
  • UNSPSC Code
  • 41115711
  • USP Designation
  • L34
  • Brand
  • Hi-Plex
  • Endcapped
  • No
  • Guard Column
  • Yes
  • Hardware
  • Cartridge
  • Maximum Temperature
  • 90 °C
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 8 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 7-7
  • Pressure Rating
  • 50 bar
  • Separation Mode
  • Ion Exclusion/Ligand Exchange
PL1670-0830 Hi-Plex H, 3.0 x 5.0 mm, 8 µm Guard cartridges, 2/pk 252 
Add to Cart
  • Inner Diameter (ID)
  • 3 mm
  • Length
  • 5 mm
  • Phase
  • H
  • UNSPSC Code
  • 41115711
  • USP Designation
  • L17L22
  • Brand
  • Hi-Plex
  • Endcapped
  • No
  • Guard Column
  • Yes
  • Hardware
  • Cartridge
  • Maximum Temperature
  • 70 °C
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 8 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 0-7
  • Pressure Rating
  • 50 bar
  • Separation Mode
  • Ion Exclusion/Ligand Exchange
PL1670-0840 Hi-Plex Na (Octo), 3.0 x 5.0 mm, 8 µm Guard cartridges, 2/pk 252 
Add to Cart
  • Inner Diameter (ID)
  • 3 mm
  • Length
  • 5 mm
  • Phase
  • Na
  • UNSPSC Code
  • 41115711
  • USP Designation
  • L58
  • Brand
  • Hi-Plex
  • Endcapped
  • No
  • Guard Column
  • Yes
  • Hardware
  • Cartridge
  • Maximum Temperature
  • 90 °C
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 8 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 7-13
  • Pressure Rating
  • 50 bar
  • Separation Mode
  • Ion Exclusion/Ligand Exchange
PL1670-0850 Hi-Plex Ca (Duo), 3.0 x 5.0 mm, 8 µm Guard cartridges, 2/pk 252 
Add to Cart
  • Inner Diameter (ID)
  • 3 mm
  • Length
  • 5 mm
  • Phase
  • Ca
  • UNSPSC Code
  • 41115711
  • USP Designation
  • L19
  • Brand
  • Hi-Plex
  • Endcapped
  • No
  • Guard Column
  • Yes
  • Hardware
  • Cartridge
  • Maximum Temperature
  • 90 °C
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 8 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 7-7
  • Pressure Rating
  • 50 bar
  • Separation Mode
  • Ion Exclusion/Ligand Exchange
PL1670-0860 Hi-Plex K, 3.0 x 5.0 mm, 8 µm Guard cartridges, 2/pk 252 
Add to Cart
  • Inner Diameter (ID)
  • 3 mm
  • Length
  • 5 mm
  • Phase
  • K
  • UNSPSC Code
  • 41115711
  • Brand
  • Hi-Plex
  • Endcapped
  • No
  • Guard Column
  • Yes
  • Hardware
  • Cartridge
  • Maximum Temperature
  • 90 °C
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 8 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 7-7
  • Pressure Rating
  • 50 bar
  • Separation Mode
  • Ion Exclusion/Ligand Exchange
PL1671-0140 Hi-Plex Na, 3.0 x 5.0 mm, 10 µm Guard cartridges, 2/pk 252 
Add to Cart
  • Inner Diameter (ID)
  • 3 mm
  • Length
  • 5 mm
  • Phase
  • Na
  • UNSPSC Code
  • 41115711
  • USP Designation
  • L58
  • Brand
  • Hi-Plex
  • Endcapped
  • No
  • Guard Column
  • Yes
  • Hardware
  • Cartridge
  • Maximum Temperature
  • 90 °C
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 10 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 7-7
  • Pressure Rating
  • 25 bar
  • Separation Mode
  • Ion Exclusion/Ligand Exchange

Overview

The small molecule column portfolio includes state-of-the-art superficially porous InfinityLab Poroshell 120 columns as well as traditional fully porous ZORBAX, Polaris, and Pursuit columns.

When you choose Agilent small molecule LC columns, you get more than just a dependable product. You also get unmatched technical support from the world’s largest chromatography supplier.


Agilent gel permeation chromatography (GPC) and size exclusion chromatography (SEC) columns and standards have been the top-selling in the polymer industry for over 40 years. GPC and SEC is used to determine the molecular weight and size distribution of macromolecules. SEC and GPC columns generate accurate, reliable data for critical polymer parameters, including dispersity (PDI), molecular weight mass average (Mw), number average (Mn), and z-average (Mz).


The importance of understanding the attributes of a biologic drug, and the processes used to create it, cannot be underestimated.  Agilent AdvanceBio LC columns are designed and produced to provide results you can be sure of when analyzing highly complex biotherapeutic molecules and monitoring their purity, potency, and other critical quality attributes.



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