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Agilent offers the largest, most modern liquid chromatography (LC) column portfolios for small molecule analysis, with columns suitable for nearly all separation modes and applications.


Whether you are performing conventional or ultra-fast chromatography, separating biomolecules, or analyzing complex compounds, the industry’s highest-performing compounds deliver fast, reproducible results – all engineered with unparalleled quality and reliability.

Catalog No. Product Net Price
AGIL820750-941 AdvanceBio Oligonucleotide, 4.6 mm, guard, 4µm. HPLC columns offer a high-quality, high-resolution IP-RP column chemistry platform that support analytical characterization through purification with method scale-up. The 4.6 mm, 4µm fast guard is a phased m 634 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 5 mm
  • Phase
  • HPH-C18
  • Brand
  • AdvanceBio Oligonucleotide
  • Guard Column
  • No
  • Hardware
  • SS
  • LC Platform
  • HPLC
  • Maximum Temperature
  • 65 °C
  • Particle Size
  • 4 µm
  • Particle Type
  • Superficially Porous
  • pH Range
  • 3-11
  • Pore Size
  • 120 Å
  • Pressure Rating
  • 600 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC & LC/MS
AGIL821725-921 AdvanceBio Oligonucleotide, 2.1 mm, fast guard 636 
Add to Cart
  • Inner Diameter (ID)
  • 2.1 mm
  • Length
  • 5 mm
  • Phase
  • HPH-C18
  • UNSPSC Code
  • 41115711
  • Brand
  • AdvanceBio Oligonucleotide
  • Guard Column
  • Yes
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 65 °C
  • Part Number Application
  • Oligos
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 2.7 µm
  • Particle Type
  • Superficially Porous
  • pH Range
  • 3-11
  • Pore Size
  • 120 Å
  • Pressure Rating
  • 600 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC & LC/MS
AGIL651750-902 AdvanceBio Peptide Mapping 120Å, 2.1 x 250 mm, 2.7 µm 1028 
Add to Cart
  • Inner Diameter (ID)
  • 2.1 mm
  • Length
  • 250 mm
  • Phase
  • C18
  • UNSPSC Code
  • 41115711
  • Brand
  • AdvanceBio Peptide Mapping
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 60 °C
  • Part Number Application
  • Peptide Mapping
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 2.7 µm
  • Particle Type
  • Superficially Porous
  • pH Range
  • 2-8
  • Pore Size
  • 120 Å
  • Pressure Rating
  • 600 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC LC & LC/MS
AGIL653750-902 AdvanceBio Peptide Mapping 120Å, 2.1 x 150 mm, 2.7 µm 872 
Add to Cart
  • Inner Diameter (ID)
  • 2.1 mm
  • Length
  • 150 mm
  • Phase
  • C18
  • UNSPSC Code
  • 41115711
  • Brand
  • AdvanceBio Peptide Mapping
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 60 °C
  • Part Number Application
  • Peptide Mapping
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 2.7 µm
  • Particle Type
  • Superficially Porous
  • pH Range
  • 2-8
  • Pore Size
  • 120 Å
  • Pressure Rating
  • 600 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC LC & LC/MS
AGIL655750-902 AdvanceBio Peptide Mapping 120Å, 2.1 x 100 mm, 2.7 µm 800 
Add to Cart
  • Inner Diameter (ID)
  • 2.1 mm
  • Length
  • 100 mm
  • Phase
  • C18
  • UNSPSC Code
  • 41115711
  • Brand
  • AdvanceBio Peptide Mapping
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 60 °C
  • Part Number Application
  • Peptide Mapping
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 2.7 µm
  • Particle Type
  • Superficially Porous
  • pH Range
  • 2-8
  • Pore Size
  • 120 Å
  • Pressure Rating
  • 600 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC LC & LC/MS
AGIL851725-911 AdvanceBio Peptide Mapping 120Å, 2.1 x 5 mm, 2.7 µm, guard, 3/pk 629 
Add to Cart
  • Inner Diameter (ID)
  • 2.1 mm
  • Length
  • 5 mm
  • Phase
  • C18
  • UNSPSC Code
  • 41115709
  • Brand
  • AdvanceBio Peptide Mapping
  • Guard Column
  • Yes
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 60 °C
  • Part Number Application
  • Peptide Mapping
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 2.7 µm
  • Particle Type
  • Superficially Porous
  • pH Range
  • 2-8
  • Pore Size
  • 120 Å
  • Pressure Rating
  • 600 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC LC & LC/MS
AGIL5065-9925 AdvanceBio Peptide Mapping, 0.075 x 150 mm, 2.7 µm, LC column 681 
Add to Cart
  • Inner Diameter (ID)
  • 0.075 mm
  • Length
  • 150 mm
  • Phase
  • C18
  • UNSPSC Code
  • 41115711
  • Brand
  • AdvanceBio Peptide Mapping
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 60 °C
  • Part Number Application
  • Peptide Mapping
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 2.7 µm
  • Particle Type
  • Superficially Porous
  • pH Range
  • 2-8
  • Pore Size
  • 120 Å
  • Pressure Rating
  • 600 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC LC & LC/MS
AGIL5065-9946 AdvanceBio Peptide Mapping Guard, 0.3 x 5.0 mm, 2.7 µm, 5 pack 417 
Add to Cart
  • Inner Diameter (ID)
  • 0.3 mm
  • Length
  • 50 mm
  • Phase
  • C18
  • UNSPSC Code
  • 41115711
  • USP Designation
  • L1
  • Brand
  • AdvanceBio Peptide Mapping
  • Guard Column
  • Yes
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 60 °C
  • Part Number Application
  • Peptide Mapping
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 2.7 µm
  • Particle Type
  • Superficially Porous
  • pH Range
  • 2-8
  • Pore Size
  • 120 Å
  • Pressure Rating
  • 600 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC LC & LC/MS
AGIL653950-302 AdvanceBio Peptide Mapping 120Å, 3.0 x 150 mm, 2.7 µm 872 
Add to Cart
  • Inner Diameter (ID)
  • 3 mm
  • Length
  • 150 mm
  • Phase
  • C18
  • UNSPSC Code
  • 41115711
  • Brand
  • AdvanceBio Peptide Mapping
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 60 °C
  • Part Number Application
  • Peptide Mapping
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 2.7 µm
  • Particle Type
  • Superficially Porous
  • pH Range
  • 2-8
  • Pore Size
  • 120 Å
  • Pressure Rating
  • 600 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC LC & LC/MS
AGIL653950-902 AdvanceBio Peptide Mapping 120Å, 4.6 x 150 mm, 2.7 µm 872 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 150 mm
  • Phase
  • C18
  • UNSPSC Code
  • 41115711
  • Brand
  • AdvanceBio Peptide Mapping
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 60 °C
  • Part Number Application
  • Peptide Mapping
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 2.7 µm
  • Particle Type
  • Superficially Porous
  • pH Range
  • 2-8
  • Pore Size
  • 120 Å
  • Pressure Rating
  • 600 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC LC & LC/MS

Overview

The small molecule column portfolio includes state-of-the-art superficially porous InfinityLab Poroshell 120 columns as well as traditional fully porous ZORBAX, Polaris, and Pursuit columns.

When you choose Agilent small molecule LC columns, you get more than just a dependable product. You also get unmatched technical support from the world’s largest chromatography supplier.


Agilent gel permeation chromatography (GPC) and size exclusion chromatography (SEC) columns and standards have been the top-selling in the polymer industry for over 40 years. GPC and SEC is used to determine the molecular weight and size distribution of macromolecules. SEC and GPC columns generate accurate, reliable data for critical polymer parameters, including dispersity (PDI), molecular weight mass average (Mw), number average (Mn), and z-average (Mz).


The importance of understanding the attributes of a biologic drug, and the processes used to create it, cannot be underestimated.  Agilent AdvanceBio LC columns are designed and produced to provide results you can be sure of when analyzing highly complex biotherapeutic molecules and monitoring their purity, potency, and other critical quality attributes.



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