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Agilent offers the largest, most modern liquid chromatography (LC) column portfolios for small molecule analysis, with columns suitable for nearly all separation modes and applications.


Whether you are performing conventional or ultra-fast chromatography, separating biomolecules, or analyzing complex compounds, the industry’s highest-performing compounds deliver fast, reproducible results – all engineered with unparalleled quality and reliability.

Catalog No. Product Net Price
AGIL823750-946 AdvanceBio Amino Acid Analysis (AAA), 3.0 x 5 mm, guard column, 3/pk 725 
Add to Cart
  • Inner Diameter (ID)
  • 3 mm
  • Length
  • 5 mm
  • Phase
  • C18
  • UNSPSC Code
  • 41115709
  • Brand
  • AdvanceBio Amino Acid Analysis
  • Guard Column
  • Yes
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 65 °C
  • Part Number Application
  • Amino Acid Analysis
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 2.7 µm
  • Particle Type
  • Superficially Porous
  • pH Range
  • 3-11
  • Pore Size
  • 100 Å
  • Pressure Rating
  • 600 bar
  • Separation Mode
  • HILIC Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC
PL1612-1102 AdvanceBio Desalting-RP, 2.1 mm, 12.5 mm, 3/pk. Requires Cartridge Holder, P/N 820999-901 available separately 530 
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  • Inner Diameter (ID)
  • 2.1 mm
  • Length
  • 12.5 mm
  • Phase
  • DVB
  • UNSPSC Code
  • 41115711
  • Brand
  • PLRP-S
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 80 °C
  • Part Number Application
  • Aggregate & Fragment AnalysisMonoclonal Antibodies (mABs)PeptidesProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-13
  • Pore Size
  • 1000 Å
  • Pressure Rating
  • 100 bar
  • Separation Mode
  • Polymeric Reversed Phase
  • Technique
  • LC & LC/MS
AGIL675775-902 AdvanceBio EC-C18, 2.1x100mm, 2.7um, PEEK 1172 
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  • Inner Diameter (ID)
  • 2.1 mm
  • Length
  • 100 mm
  • Phase
  • EC-C18
  • Brand
  • AdvanceBio Peptide Mapping
  • Hardware
  • PEEK Lined SS
  • LC Platform
  • BioInert
  • Particle Size
  • 2.7 µm
  • Separation Mode
  • Reversed Phase
AGIL679775-902 AdvanceBio EC-C18,2.1x50mm,2.7um,PEEK 1017 
Add to Cart
  • Inner Diameter (ID)
  • 2.1 mm
  • Length
  • 50 mm
  • Phase
  • EC-C18
  • Brand
  • AdvanceBio Peptide Mapping
  • Hardware
  • PEEK Lined SS
  • LC Platform
  • BioInert
  • Particle Size
  • 2.7 µm
  • Separation Mode
  • Reversed Phase
AGIL651750-913 AdvanceBio Glycan Mapping 120Å, 2.1 x 250 mm, 2.7 µm. This column has superficially porous particles with amide HILIC chemistry for high resolution at <600 bar pressure. 1102 
Add to Cart
  • Inner Diameter (ID)
  • 2.1 mm
  • Length
  • 250 mm
  • Phase
  • Amide HILIC
  • UNSPSC Code
  • 41115711
  • Brand
  • AdvanceBio Glycan Mapping
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 40 °C
  • Part Number Application
  • Glycan Analysis
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 2.7 µm
  • Particle Type
  • Superficially Porous
  • pH Range
  • 2-7
  • Pore Size
  • 120 Å
  • Pressure Rating
  • 600 bar
  • Separation Mode
  • HILIC
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC & LC/MS
AGIL680975-913 AdvanceBio Glycan Mapping 120Å, 4.6 x 250 mm, 2.7 µm. This column has superficially porous particles with amide HILIC chemistry for high resolution at <600 bar pressure. 1153 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 250 mm
  • Phase
  • Amide HILIC
  • UNSPSC Code
  • 41115711
  • Brand
  • AdvanceBio Glycan Mapping
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 40 °C
  • Part Number Application
  • Glycan Analysis
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 2.7 µm
  • Particle Type
  • Superficially Porous
  • pH Range
  • 2-7
  • Pore Size
  • 120 Å
  • Pressure Rating
  • 600 bar
  • Separation Mode
  • HILIC
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC & LC/MS
AGIL683775-913 AdvanceBio Glycan Mapping 120Å, 2.1 x 150 mm, 2.7 µm. This column has superficially porous particles with amide HILIC chemistry for high resolution at <600 bar pressure. 936 
Add to Cart
  • Inner Diameter (ID)
  • 2.1 mm
  • Length
  • 150 mm
  • Phase
  • Amide HILIC
  • UNSPSC Code
  • 41115711
  • Brand
  • AdvanceBio Glycan Mapping
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 40 °C
  • Part Number Application
  • Glycan Analysis
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 2.7 µm
  • Particle Type
  • Superficially Porous
  • pH Range
  • 2-7
  • Pore Size
  • 120 Å
  • Pressure Rating
  • 600 bar
  • Separation Mode
  • HILIC
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC & LC/MS
AGIL683975-913 AdvanceBio Glycan Mapping 120Å, 4.6 x 150 mm, 2.7 µm. This column has superficially porous particles with amide HILIC chemistry for high resolution at <600 bar pressure. 936 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 150 mm
  • Phase
  • Amide HILIC
  • UNSPSC Code
  • 41115711
  • Brand
  • AdvanceBio Glycan Mapping
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 40 °C
  • Part Number Application
  • Glycan Analysis
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 2.7 µm
  • Particle Type
  • Superficially Porous
  • pH Range
  • 2-7
  • Pore Size
  • 120 Å
  • Pressure Rating
  • 600 bar
  • Separation Mode
  • HILIC
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC & LC/MS
AGIL685775-913 AdvanceBio Glycan Mapping 120Å, 2.1 x 100 mm, 2.7 µm. This column has superficially porous particles with amide HILIC chemistry for high resolution at <600 bar pressure. 859 
Add to Cart
  • Inner Diameter (ID)
  • 2.1 mm
  • Length
  • 100 mm
  • Phase
  • Amide HILIC
  • UNSPSC Code
  • 41115711
  • Brand
  • AdvanceBio Glycan Mapping
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 40 °C
  • Part Number Application
  • Glycan Analysis
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 2.7 µm
  • Particle Type
  • Superficially Porous
  • pH Range
  • 2-7
  • Pore Size
  • 120 Å
  • Pressure Rating
  • 600 bar
  • Separation Mode
  • HILIC
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC & LC/MS
AGIL685975-913 AdvanceBio Glycan Mapping 120Å, 4.6 x 100 mm, 2.7 µm. This column has superficially porous particles with amide HILIC chemistry for high resolution at <600 bar pressure. 859 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 100 mm
  • Phase
  • Amide HILIC
  • UNSPSC Code
  • 41115711
  • Brand
  • AdvanceBio Glycan Mapping
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 40 °C
  • Part Number Application
  • Glycan Analysis
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 2.7 µm
  • Particle Type
  • Superficially Porous
  • pH Range
  • 2-7
  • Pore Size
  • 120 Å
  • Pressure Rating
  • 600 bar
  • Separation Mode
  • HILIC
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC & LC/MS

Overview

The small molecule column portfolio includes state-of-the-art superficially porous InfinityLab Poroshell 120 columns as well as traditional fully porous ZORBAX, Polaris, and Pursuit columns.

When you choose Agilent small molecule LC columns, you get more than just a dependable product. You also get unmatched technical support from the world’s largest chromatography supplier.


Agilent gel permeation chromatography (GPC) and size exclusion chromatography (SEC) columns and standards have been the top-selling in the polymer industry for over 40 years. GPC and SEC is used to determine the molecular weight and size distribution of macromolecules. SEC and GPC columns generate accurate, reliable data for critical polymer parameters, including dispersity (PDI), molecular weight mass average (Mw), number average (Mn), and z-average (Mz).


The importance of understanding the attributes of a biologic drug, and the processes used to create it, cannot be underestimated.  Agilent AdvanceBio LC columns are designed and produced to provide results you can be sure of when analyzing highly complex biotherapeutic molecules and monitoring their purity, potency, and other critical quality attributes.



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