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Agilent offers the largest, most modern liquid chromatography (LC) column portfolios for small molecule analysis, with columns suitable for nearly all separation modes and applications.


Whether you are performing conventional or ultra-fast chromatography, separating biomolecules, or analyzing complex compounds, the industry’s highest-performing compounds deliver fast, reproducible results – all engineered with unparalleled quality and reliability.

Catalog No. Product Net Price
PL1512-5801 PLRP-S 300Å, 4.6 x 250 mm, 8 µm 961 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 250 mm
  • Phase
  • DVB
  • UNSPSC Code
  • 41115711
  • Brand
  • PLRP-S
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 200 °C
  • Part Number Application
  • Aggregate & Fragment AnalysisMonoclonal Antibodies (mABs)PeptidesProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 8 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-14
  • Pore Size
  • 300 Å
  • Pressure Rating
  • 207 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC LC & LC/MS
PL1512-5802 PLRP-S 1000Å, 4.6 x 250 mm, 8 µm 950 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 250 mm
  • Phase
  • DVB
  • UNSPSC Code
  • 41115711
  • Brand
  • PLRP-S
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 200 °C
  • Part Number Application
  • Aggregate & Fragment AnalysisMonoclonal Antibodies (mABs)PeptidesProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 8 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-14
  • Pore Size
  • 1000 Å
  • Pressure Rating
  • 207 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC LC & LC/MS
PL1612-1801 PLRP-S 300Å, 3 x 5 mm, 5 µm, guard cartridge (PL), 2/pk 156 
Add to Cart
  • Inner Diameter (ID)
  • 3 mm
  • Length
  • 5 mm
  • Phase
  • DVB
  • UNSPSC Code
  • 41115711
  • Brand
  • PLRP-S
  • Guard Column
  • Yes
  • Maximum Temperature
  • 80 °C
  • Part Number Application
  • Aggregate & Fragment AnalysisMonoclonal Antibodies (mABs)PeptidesProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • Pore Size
  • 300 Å
  • Separation Mode
  • Reversed Phase
  • Technique
  • LC LC & LC/MS
PL1712-3101 PLRP-S 300Å, 50 x 150 mm, 10 µm 9925 
Add to Cart
  • Inner Diameter (ID)
  • 50 mm
  • Length
  • 150 mm
  • Phase
  • DVB
  • UNSPSC Code
  • 41115711
  • Brand
  • PLRP-S
  • Hardware
  • SS
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 200 °C
  • Part Number Application
  • Peptides Preparative HPLC Columns & Bulk MediaProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 10 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-14
  • Pore Size
  • 300 Å
  • Pressure Rating
  • 207 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC LC & LC/MS
PL1712-3102 PLRP-S 1000Å, 50 x 150 mm, 10 µm 10805 
Add to Cart
  • Inner Diameter (ID)
  • 50 mm
  • Length
  • 150 mm
  • Phase
  • DVB
  • UNSPSC Code
  • 41115711
  • Brand
  • PLRP-S
  • Hardware
  • SS
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 200 °C
  • Part Number Application
  • Peptides Preparative HPLC Columns & Bulk MediaProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 10 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-14
  • Pore Size
  • 1000 Å
  • Pressure Rating
  • 207 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC LC & LC/MS
PL1712-3103 PLRP-S 4000Å, 50 x 150 mm, 10 µm 10805 
Add to Cart
  • Inner Diameter (ID)
  • 50 mm
  • Length
  • 150 mm
  • Phase
  • DVB
  • UNSPSC Code
  • 41115711
  • Brand
  • PLRP-S
  • Hardware
  • SS
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 200 °C
  • Part Number Application
  • Peptides Preparative HPLC Columns & Bulk MediaProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 10 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-14
  • Pore Size
  • 4000 Å
  • Pressure Rating
  • 207 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC LC & LC/MS
PL1712-3201 PLRP-S 300Å, 50 x 150 mm, 15-20 µm 8364 
Add to Cart
  • Inner Diameter (ID)
  • 50 mm
  • Length
  • 150 mm
  • Phase
  • DVB
  • UNSPSC Code
  • 41115711
  • Brand
  • PLRP-S
  • Hardware
  • SS
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 200 °C
  • Part Number Application
  • Peptides Preparative HPLC Columns & Bulk MediaProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 20 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-14
  • Pore Size
  • 300 Å
  • Pressure Rating
  • 103 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC LC & LC/MS
PL1712-3400 PLRP-S 100Å, 50 x 150 mm, 10-15 µm 8164 
Add to Cart
  • Inner Diameter (ID)
  • 50 mm
  • Length
  • 150 mm
  • Phase
  • DVB
  • UNSPSC Code
  • 41115711
  • Brand
  • PLRP-S
  • Hardware
  • SS
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 200 °C
  • Part Number Application
  • Peptides Preparative HPLC Columns & Bulk MediaProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 10 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-14
  • Pore Size
  • 100 Å
  • Pressure Rating
  • 103 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC LC & LC/MS
PL1712-3401 PLRP-S 300Å, 50 x 150 mm, 10-15 µm 9019 
Add to Cart
  • Inner Diameter (ID)
  • 50 mm
  • Length
  • 150 mm
  • Phase
  • DVB
  • UNSPSC Code
  • 41115711
  • Brand
  • PLRP-S
  • Hardware
  • SS
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 200 °C
  • Part Number Application
  • Peptides Preparative HPLC Columns & Bulk MediaProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 10 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-14
  • Pore Size
  • 300 Å
  • Pressure Rating
  • 103 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC LC & LC/MS
PL1712-3703 PLRP-S 4000Å, 50 x 150 mm, 30 µm 9107 
Add to Cart
  • Inner Diameter (ID)
  • 50 mm
  • Length
  • 150 mm
  • Phase
  • DVB
  • UNSPSC Code
  • 41115711
  • Brand
  • PLRP-S
  • Hardware
  • SS
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 200 °C
  • Part Number Application
  • Peptides Preparative HPLC Columns & Bulk MediaProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 30 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-14
  • Pore Size
  • 4000 Å
  • Pressure Rating
  • 103 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC LC & LC/MS

Overview

The small molecule column portfolio includes state-of-the-art superficially porous InfinityLab Poroshell 120 columns as well as traditional fully porous ZORBAX, Polaris, and Pursuit columns.

When you choose Agilent small molecule LC columns, you get more than just a dependable product. You also get unmatched technical support from the world’s largest chromatography supplier.


Agilent gel permeation chromatography (GPC) and size exclusion chromatography (SEC) columns and standards have been the top-selling in the polymer industry for over 40 years. GPC and SEC is used to determine the molecular weight and size distribution of macromolecules. SEC and GPC columns generate accurate, reliable data for critical polymer parameters, including dispersity (PDI), molecular weight mass average (Mw), number average (Mn), and z-average (Mz).


The importance of understanding the attributes of a biologic drug, and the processes used to create it, cannot be underestimated.  Agilent AdvanceBio LC columns are designed and produced to provide results you can be sure of when analyzing highly complex biotherapeutic molecules and monitoring their purity, potency, and other critical quality attributes.



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