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Agilent offers the largest, most modern liquid chromatography (LC) column portfolios for small molecule analysis, with columns suitable for nearly all separation modes and applications.


Whether you are performing conventional or ultra-fast chromatography, separating biomolecules, or analyzing complex compounds, the industry’s highest-performing compounds deliver fast, reproducible results – all engineered with unparalleled quality and reliability.

Catalog No. Product Net Price
A2014100X046 Polaris NH2 HPLC column, 180 Å, 3 µm, 100 x 4.6 mm, 1/pk 711 
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  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 100 mm
  • Phase
  • NH2
  • UNSPSC Code
  • 41115711
  • USP Designation
  • L8
  • Brand
  • Polaris
  • Carbon Load
  • 5.5 %
  • Endcapped
  • Amide
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 3 µm
  • Particle Type
  • Fully Porous
  • Pore Size
  • 180 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • HILIC Normal Phase Reversed Phase SFC
PSA080505 PolarSil, 8 x 50 mm, 5 µm. GPC/SEC guard column, ships in DMAc 591 
Add to Cart
  • Inner Diameter (ID)
  • 8 mm
  • Length
  • 50 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • PolarSil
  • Guard Column
  • Yes
  • Maximum Temperature
  • 70 °C
  • Particle Size
  • 5 µm
  • Pressure Rating
  • 120 bar
  • Shipping Solvent
  • DMAc
PSA0830051E2 PolarSil, 100Å, 8 x 300 mm, 5 µm. GPC/SEC column, molecular weight range 100 to 4x10^4, ships in DMAc 1959 
Add to Cart
  • Inner Diameter (ID)
  • 8 mm
  • Length
  • 300 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • PolarSil
  • Guard Column
  • No
  • Maximum Temperature
  • 70 °C
  • Molecular Weight Lower Limit
  • 100 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Individual Pore Size
  • Pore Size
  • 100 µm
  • Pressure Rating
  • 120 bar
  • Shipping Solvent
  • DMAc
PSA0830051E3 PolarSil, 1000Å, 8 x 300 mm, 5 µm. GPC/SEC column, molecular weight range 10^4 to 10^6, ships in DMAc 1959 
Add to Cart
  • Inner Diameter (ID)
  • 8 mm
  • Length
  • 300 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • PolarSil
  • Guard Column
  • No
  • Maximum Temperature
  • 70 °C
  • Molecular Weight Lower Limit
  • 10000 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Individual Pore Size
  • Pore Size
  • 1000 µm
  • Pressure Rating
  • 120 bar
  • Shipping Solvent
  • DMAc
PSA083005LIM PolarSil, Linear-M, 8 x 300 mm, 5 µm. GPC/SEC column, molecular weight range 100 to 10^6, ships in DMAc 2180 
Add to Cart
  • Inner Diameter (ID)
  • 8 mm
  • Length
  • 300 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • PolarSil
  • Guard Column
  • No
  • Maximum Temperature
  • 70 °C
  • Molecular Weight Lower Limit
  • 100 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Mixed Pore Size
  • Pressure Rating
  • 120 bar
  • Shipping Solvent
  • DMAc
PSA083005LIS PolarSil, Linear-S, 8 x 300 mm, 5 µm. GPC/SEC column, molecular weight range 100 to 3x10^5, ships in DMAc 2180 
Add to Cart
  • Inner Diameter (ID)
  • 8 mm
  • Length
  • 300 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • PolarSil
  • Guard Column
  • No
  • Maximum Temperature
  • 70 °C
  • Molecular Weight Lower Limit
  • 100 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Mixed Pore Size
  • Pressure Rating
  • 120 bar
  • Shipping Solvent
  • DMAc
PSM050303 PolarSil, 4.6 x 30 mm, 3 µm. GPC/SEC guard column, ships in DMAc 591 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 30 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • PolarSil
  • Guard Column
  • Yes
  • Maximum Temperature
  • 70 °C
  • Particle Size
  • 3 µm
  • Pressure Rating
  • 150 bar
  • Shipping Solvent
  • DMAc
PSM0525031E2 PolarSil, 100Å, 4.6 x 250 mm, 3 µm. GPC/SEC column, molecular weight range 100 to 4x10^4, ships in DMAc 2180 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 250 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • PolarSil
  • Guard Column
  • No
  • Maximum Temperature
  • 70 °C
  • Molecular Weight Lower Limit
  • 100 Da
  • Particle Size
  • 3 µm
  • Particle Type
  • Individual Pore Size
  • Pore Size
  • 100 µm
  • Pressure Rating
  • 150 bar
  • Shipping Solvent
  • DMAc
PSM0525031E3 PolarSil, 1000Å, 4.6 x 250 mm, 3 µm. GPC/SEC column, molecular weight range 10^4 to 10^6, ships in DMAc 2180 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 250 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • PolarSil
  • Guard Column
  • No
  • Maximum Temperature
  • 70 °C
  • Molecular Weight Lower Limit
  • 10000 Da
  • Particle Size
  • 3 µm
  • Particle Type
  • Individual Pore Size
  • Pore Size
  • 1000 µm
  • Pressure Rating
  • 150 bar
  • Shipping Solvent
  • DMAc
PSM0525033E2 PolarSil, 300Å, 4.6 x 250 mm, 3 µm. GPC/SEC column, molecular weight range 1000 to 3x10^5, ships in DMAc 2180 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 250 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • PolarSil
  • Guard Column
  • No
  • Maximum Temperature
  • 70 °C
  • Molecular Weight Lower Limit
  • 1000 Da
  • Particle Size
  • 3 µm
  • Particle Type
  • Individual Pore Size
  • Pore Size
  • 300 µm
  • Pressure Rating
  • 150 bar
  • Shipping Solvent
  • DMAc

Overview

The small molecule column portfolio includes state-of-the-art superficially porous InfinityLab Poroshell 120 columns as well as traditional fully porous ZORBAX, Polaris, and Pursuit columns.

When you choose Agilent small molecule LC columns, you get more than just a dependable product. You also get unmatched technical support from the world’s largest chromatography supplier.


Agilent gel permeation chromatography (GPC) and size exclusion chromatography (SEC) columns and standards have been the top-selling in the polymer industry for over 40 years. GPC and SEC is used to determine the molecular weight and size distribution of macromolecules. SEC and GPC columns generate accurate, reliable data for critical polymer parameters, including dispersity (PDI), molecular weight mass average (Mw), number average (Mn), and z-average (Mz).


The importance of understanding the attributes of a biologic drug, and the processes used to create it, cannot be underestimated.  Agilent AdvanceBio LC columns are designed and produced to provide results you can be sure of when analyzing highly complex biotherapeutic molecules and monitoring their purity, potency, and other critical quality attributes.



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