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Agilent offers the largest, most modern liquid chromatography (LC) column portfolios for small molecule analysis, with columns suitable for nearly all separation modes and applications.


Whether you are performing conventional or ultra-fast chromatography, separating biomolecules, or analyzing complex compounds, the industry’s highest-performing compounds deliver fast, reproducible results – all engineered with unparalleled quality and reliability.

Catalog No. Product Net Price
A2021250X020 Polaris 180Å C18-Ether, 2.0 x 250 mm, 3 µm HPLC column 836 
Add to Cart
  • Inner Diameter (ID)
  • 2 mm
  • Length
  • 250 mm
  • Phase
  • C18-Ether
  • UNSPSC Code
  • 41115709
  • Brand
  • Polaris
  • Carbon Load
  • 12.1 %
  • Endcapped
  • Yes
  • Guard Column
  • No
  • Hardware
  • Conventional
  • Maximum Temperature
  • 60 °C
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 3 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-8
  • Pore Size
  • 180 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
A2021250X046 Polaris 180Å C18-Ether, 4.6 x 250 mm, 3 µm HPLC column 836 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 250 mm
  • Phase
  • C18-Ether
  • UNSPSC Code
  • 41115709
  • Brand
  • Polaris
  • Carbon Load
  • 12.1 %
  • Endcapped
  • Yes
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC
  • Maximum Temperature
  • 60 °C
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 3 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-8
  • Pore Size
  • 180 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
A2030050X020 Polaris 180Å C8-Ether, 2.0 x 50 mm, 5 µm HPLC column 520 
Add to Cart
  • Inner Diameter (ID)
  • 2 mm
  • Length
  • 50 mm
  • Phase
  • C8-Ether
  • UNSPSC Code
  • 41115709
  • Brand
  • Polaris
  • Carbon Load
  • 7.1 %
  • Endcapped
  • Yes
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC
  • Maximum Temperature
  • 60 °C
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-8
  • Pore Size
  • 180 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
A2030150X020 Polaris 180Å C8-Ether, 2.0 x 150 mm, 5 µm HPLC column 724 
Add to Cart
  • Inner Diameter (ID)
  • 2 mm
  • Length
  • 150 mm
  • Phase
  • C8-Ether
  • UNSPSC Code
  • 41115709
  • Brand
  • Polaris
  • Carbon Load
  • 7.1 %
  • Endcapped
  • Yes
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC
  • Maximum Temperature
  • 60 °C
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-8
  • Pore Size
  • 180 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
A2030150X046 Polaris 180Å C8-Ether, 4.6 x 150 mm, 5 µm HPLC column 724 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 150 mm
  • Phase
  • C8-Ether
  • UNSPSC Code
  • 41115709
  • Brand
  • Polaris
  • Carbon Load
  • 7.1 %
  • Endcapped
  • Yes
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC
  • Maximum Temperature
  • 60 °C
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-8
  • Pore Size
  • 180 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
A2030250X020 Polaris 180Å C8-Ether, 2.0 x 250 mm, 5 µm HPLC column 769 
Add to Cart
  • Inner Diameter (ID)
  • 2 mm
  • Length
  • 250 mm
  • Phase
  • C8-Ether
  • UNSPSC Code
  • 41115709
  • Brand
  • Polaris
  • Carbon Load
  • 7.1 %
  • Endcapped
  • Yes
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC
  • Maximum Temperature
  • 60 °C
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-8
  • Pore Size
  • 180 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
A2030250X100 Polaris 180Å C8-Ether, 10 x 250 mm, 5 µm HPLC column 2564 
Add to Cart
  • Inner Diameter (ID)
  • 10 mm
  • Length
  • 250 mm
  • Phase
  • C8-Ether
  • UNSPSC Code
  • 41115709
  • Brand
  • Polaris
  • Carbon Load
  • 7.1 %
  • Endcapped
  • Yes
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 60 °C
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-8
  • Pore Size
  • 180 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
A2031050X020 Polaris 180Å C8-Ether, 2.0 x 50 mm, 3 µm HPLC column 520 
Add to Cart
  • Inner Diameter (ID)
  • 2 mm
  • Length
  • 50 mm
  • Phase
  • C8-Ether
  • UNSPSC Code
  • 41115709
  • Brand
  • Polaris
  • Carbon Load
  • 7.1 %
  • Endcapped
  • Yes
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC
  • Maximum Temperature
  • 60 °C
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 3 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-8
  • Pore Size
  • 180 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
A2031050X030 Polaris 180Å C8-Ether, 3.0 x 50 mm, 3 µm HPLC column 520 
Add to Cart
  • Inner Diameter (ID)
  • 3 mm
  • Length
  • 50 mm
  • Phase
  • C8-Ether
  • UNSPSC Code
  • 41115709
  • Brand
  • Polaris
  • Carbon Load
  • 7.1 %
  • Endcapped
  • Yes
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC
  • Maximum Temperature
  • 60 °C
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 3 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-8
  • Pore Size
  • 180 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
A2031050X046 Polaris 180Å C8-Ether, 4.6 x 50 mm, 3 µm HPLC column 520 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 50 mm
  • Phase
  • C8-Ether
  • UNSPSC Code
  • 41115709
  • Brand
  • Polaris
  • Carbon Load
  • 7.1 %
  • Endcapped
  • Yes
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC
  • Maximum Temperature
  • 60 °C
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 3 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-8
  • Pore Size
  • 180 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase

Overview

The small molecule column portfolio includes state-of-the-art superficially porous InfinityLab Poroshell 120 columns as well as traditional fully porous ZORBAX, Polaris, and Pursuit columns.

When you choose Agilent small molecule LC columns, you get more than just a dependable product. You also get unmatched technical support from the world’s largest chromatography supplier.


Agilent gel permeation chromatography (GPC) and size exclusion chromatography (SEC) columns and standards have been the top-selling in the polymer industry for over 40 years. GPC and SEC is used to determine the molecular weight and size distribution of macromolecules. SEC and GPC columns generate accurate, reliable data for critical polymer parameters, including dispersity (PDI), molecular weight mass average (Mw), number average (Mn), and z-average (Mz).


The importance of understanding the attributes of a biologic drug, and the processes used to create it, cannot be underestimated.  Agilent AdvanceBio LC columns are designed and produced to provide results you can be sure of when analyzing highly complex biotherapeutic molecules and monitoring their purity, potency, and other critical quality attributes.



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