These ReadyToProcess chromatography columns are prepacked with Capto adhere chromatography resin and are excellent for intermediate purification polishing and purification after protein A capture. ReadyToProcess columns are validated high-performance bioprocessing columns that are supplied prepacked and ready for use. Wide operational window of pH and conductivity. High capacity and productivity in flow-through mode. Two-step chromatographic process with protein A affinity, saves time and cuts operating costs. No cross contamination Removes contaminants to formulation levels. About Capto adhereCapto adhere is a multimodal anion exchange chromatography resin for intermediate purification and polishing of monoclonal antibodies after the Protein A capture step, giving the possibility to design a two-step chromatographic downstream process. Enables a two-step chromatographic processThe resin is composed of a rigid, high-flow agarose matrix and a novel multimodal ligand. The strong multimodal ligand gives a different selectivity compared with traditional ion exchangers. Capto adhere can remove key contaminants such as DNA, host cell proteins (HCP), leached protein A, dimers and larger aggregates, and viruses in a single step. Together with a Protein A capture step, like MabSelect SuRe, Capto adhere allows the design of a two-step chromatographic process for mAbs. For optimized performance of Capto adhere, screening and optimization of loading conditions is recommended, preferably using modern high-throughput process development tools, such as PreDictor 96-well filter plates.Key benefits of ReadyToProcess columns include:Robust column design and validated packing methods enable consistent column performance.Standardized column formats allow reduced column cost and off-the-shelf availability for short delivery lead times.Cost-savings by eliminating the need for column preparation, packing, and validation procedures.Fulfills industrial demands for security of supply, robust performance, and regulatory support.