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Agilent offers the largest, most modern liquid chromatography (LC) column portfolios for small molecule analysis, with columns suitable for nearly all separation modes and applications.


Whether you are performing conventional or ultra-fast chromatography, separating biomolecules, or analyzing complex compounds, the industry’s highest-performing compounds deliver fast, reproducible results – all engineered with unparalleled quality and reliability.

Catalog No. Product Net Price
AGIL821125-937 ZORBAX Eclipse Plus C8, 95Å, 2.1 x 12.5 mm, 5 µm, 400 bar pressure limit, guard cartridge (ZGC), 4/pk 230 
Add to Cart
  • Inner Diameter (ID)
  • 2.1 mm
  • Length
  • 13 mm
  • Phase
  • Eclipse Plus C8
  • UNSPSC Code
  • 41115709
  • USP Designation
  • L7
  • Brand
  • ZORBAX
  • Carbon Load
  • 7 %
  • Endcapped
  • Double
  • Guard Column
  • Yes
  • Hardware
  • Conventional
  • LC Platform
  • HPLC
  • Maximum Temperature
  • 40 °C at pH 6-9 60 °C at pH 2-6 40 °C at pH 6-960 °C at pH 2-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-9
  • Pore Size
  • 95 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
AGIL821700-902 ZORBAX RRHT StableBond C18, 1.8 µm, 2.1 x 15 mm cartridge (RR). 80Å, use with cartridge hardware 820555-901. 322 
Add to Cart
  • Inner Diameter (ID)
  • 2.1 mm
  • Length
  • 15 mm
  • Phase
  • SB-C18
  • UNSPSC Code
  • 41115709
  • USP Designation
  • L1
  • Brand
  • ZORBAX
  • Carbon Load
  • 10 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Cartridge
  • LC Platform
  • HPLC
  • Maximum Temperature
  • 40 °C at pH 6-8 90 °C at pH 1-6 40 °C at pH 6-890 °C at pH 1-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 1.8 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 0.8-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
AGIL821700-932 ZORBAX RRHT StableBond C18, 1.8 µm, 2.1 x 15 mm cartridge (RR), 3/pk. 80Å, use with cartridge hardware 820555-901. 788 
Add to Cart
  • Inner Diameter (ID)
  • 2.1 mm
  • Length
  • 15 mm
  • Phase
  • SB-C18
  • UNSPSC Code
  • 41115709
  • USP Designation
  • L1
  • Brand
  • ZORBAX
  • Carbon Load
  • 10 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Cartridge
  • LC Platform
  • HPLC
  • Maximum Temperature
  • 40 °C at pH 6-8 90 °C at pH 1-6 40 °C at pH 6-890 °C at pH 1-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 1.8 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 0.8-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
AGIL821725-901 ZORBAX RRHD Eclipse Plus C18, 2.1 mm, 1.8 µm, 1200 bar pressure limit, UHPLC guard, 3/pk 583 
Add to Cart
  • Inner Diameter (ID)
  • 2.1 mm
  • Length
  • 5 mm
  • Phase
  • Eclipse Plus C18
  • UNSPSC Code
  • 41115709
  • USP Designation
  • L1
  • Agency Method
  • EPA 537.1,EPA 533,ASTM D7979
  • Brand
  • ZORBAX
  • Carbon Load
  • 9 %
  • Endcapped
  • Double
  • Guard Column
  • Yes
  • Hardware
  • Conventional
  • LC Platform
  • HPLC UHPLC Low Dispersion U
  • Maximum Temperature
  • 40 °C at pH 6-9 60 °C at pH 2-6 40 °C at pH 6-960 °C at pH 2-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 1.8 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-9
  • Pore Size
  • 95 Å
  • Pressure Rating
  • 1200 bar
  • Separation Mode
  • Reversed Phase
AGIL821725-902 ZORBAX RRHD StableBond C18, 2.1 mm, 1.8 µm, 1200 bar, UHPLC guard, 3/pk 583 
Add to Cart
  • Inner Diameter (ID)
  • 2.1 mm
  • Length
  • 5 mm
  • Phase
  • SB-C18
  • UNSPSC Code
  • 41115709
  • USP Designation
  • L1
  • Agency Method
  • EPA 8327
  • Brand
  • ZORBAX
  • Carbon Load
  • 10 %
  • Endcapped
  • No
  • Guard Column
  • Yes
  • Hardware
  • Conventional
  • LC Platform
  • HPLC UHPLC Low Dispersion U
  • Maximum Temperature
  • 40 °C at pH 6-8 90 °C at pH 1-6 40 °C at pH 6-890 °C at pH 1-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 1.8 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 0.8-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 1200 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
AGIL821725-903 ZORBAX Eclipse XDB-C18, 80Å, 2.1 mm, 1.8 µm, 1200 bar pressure limit, UHPLC guard, 3/pk 583 
Add to Cart
  • Inner Diameter (ID)
  • 2.1 mm
  • Length
  • 5 mm
  • Phase
  • Eclipse XDB-C18
  • UNSPSC Code
  • 41115709
  • USP Designation
  • L1
  • Brand
  • ZORBAX
  • Carbon Load
  • 10 %
  • Endcapped
  • Double
  • Guard Column
  • Yes
  • Hardware
  • Conventional
  • LC Platform
  • HPLC UHPLC Low Dispersion U
  • Maximum Temperature
  • 40 °C at pH 6-9 60 °C at pH 2-6 40 °C at pH 6-960 °C at pH 2-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 1.8 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-9
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 1200 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
AGIL821725-907 ZORBAX Extend-C18, 80Å, 2.1 mm, 1.8 µm, 1200 bar pressure limit, UHPLC guard, 3/pk 550 
Add to Cart
  • Inner Diameter (ID)
  • 2.1 mm
  • Length
  • 5 mm
  • Phase
  • Extend-C18
  • UNSPSC Code
  • 41115709
  • USP Designation
  • L1
  • Brand
  • ZORBAX
  • Carbon Load
  • 12.5 %
  • Endcapped
  • Double
  • Guard Column
  • Yes
  • LC Platform
  • HPLC UHPLC Low Dispersion U
  • Maximum Temperature
  • 40 °C at pH 8-9 60 °C at pH 2-8 40 °C at pH 8-11.560 °C at pH 2-8
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 1.8 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-11.5
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 1200 bar
  • Separation Mode
  • Reversed Phase
AGIL821725-932 ZORBAX RRHD Eclipse Plus Phenyl-Hexyl, 2.1 mm, 1.8 μm, Plus C8, 3.0 mm, 1.8 μm, 1200 bar pressure limit, UHPLC guard, 3/pk 583 
Add to Cart
  • Inner Diameter (ID)
  • 2.1 mm
  • Length
  • 5 mm
  • Phase
  • Eclipse Plus Phenyl-Hexyl
  • UNSPSC Code
  • 41115709
  • USP Designation
  • L11
  • Brand
  • ZORBAX
  • Carbon Load
  • 9 %
  • Endcapped
  • Double
  • Guard Column
  • Yes
  • Hardware
  • Conventional
  • LC Platform
  • HPLC UHPLC Low Dispersion U
  • Maximum Temperature
  • 40 °C at pH 6-9 60 °C at pH 2-6 40 °C at pH 6-860 °C at pH 2-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 1.8 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-8
  • Pore Size
  • 95 Å
  • Pressure Rating
  • 1200 bar
  • Separation Mode
  • Reversed Phase
AGIL821725-933 ZORBAX RRHD Eclipse PAH, 95Å, 2.1 mm, 1.8 μm, 1200 bar pressure limit, UHPLC guard, 3/pk 583 
Add to Cart
  • Inner Diameter (ID)
  • 2.1 mm
  • Length
  • 5 mm
  • Phase
  • Eclipse PAH
  • UNSPSC Code
  • 41115709
  • Brand
  • ZORBAX
  • Carbon Load
  • 14 %
  • Endcapped
  • No
  • Guard Column
  • Yes
  • Hardware
  • Conventional
  • LC Platform
  • HPLC UHPLC Low Dispersion U
  • Maximum Temperature
  • 40 °C at pH 6-9 60 °C at pH 2-6 40 °C at pH 6-860 °C at pH 2-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 1.8 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-8
  • Pore Size
  • 95 Å
  • Pressure Rating
  • 1200 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
AGIL821725-935 ZORBAX RRHD StableBond Phenyl, 2.1 mm, 1.8 μm, 1200 bar, UHPLC guard, 3/pk 583 
Add to Cart
  • Inner Diameter (ID)
  • 2.1 mm
  • Length
  • 5 mm
  • Phase
  • SB-Phenyl
  • UNSPSC Code
  • 41115709
  • Brand
  • ZORBAX
  • Carbon Load
  • 5.5 %
  • Endcapped
  • No
  • Guard Column
  • Yes
  • Hardware
  • Conventional
  • LC Platform
  • HPLC UHPLC Low Dispersion U
  • Maximum Temperature
  • 40 °C at pH 6-8 80 °C at pH 1-6 40 °C at pH 6-880 °C at pH 1-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 1.8 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 1200 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water

Overview

The small molecule column portfolio includes state-of-the-art superficially porous InfinityLab Poroshell 120 columns as well as traditional fully porous ZORBAX, Polaris, and Pursuit columns.

When you choose Agilent small molecule LC columns, you get more than just a dependable product. You also get unmatched technical support from the world’s largest chromatography supplier.


Agilent gel permeation chromatography (GPC) and size exclusion chromatography (SEC) columns and standards have been the top-selling in the polymer industry for over 40 years. GPC and SEC is used to determine the molecular weight and size distribution of macromolecules. SEC and GPC columns generate accurate, reliable data for critical polymer parameters, including dispersity (PDI), molecular weight mass average (Mw), number average (Mn), and z-average (Mz).


The importance of understanding the attributes of a biologic drug, and the processes used to create it, cannot be underestimated.  Agilent AdvanceBio LC columns are designed and produced to provide results you can be sure of when analyzing highly complex biotherapeutic molecules and monitoring their purity, potency, and other critical quality attributes.



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