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Agilent offers the largest, most modern liquid chromatography (LC) column portfolios for small molecule analysis, with columns suitable for nearly all separation modes and applications.


Whether you are performing conventional or ultra-fast chromatography, separating biomolecules, or analyzing complex compounds, the industry’s highest-performing compounds deliver fast, reproducible results – all engineered with unparalleled quality and reliability.

Catalog No. Product Net Price
AGIL7995118-344 ZORBAX RR Eclipse XDB-C1, 80Å, 3.5 µm, 4.6 x 75 mm, cartridge (AC), use with cartridge hardware PN 5021-1845 609 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 75 mm
  • Phase
  • Eclipse XDB-C18
  • UNSPSC Code
  • 41115709
  • USP Designation
  • L1
  • Brand
  • ZORBAX
  • Carbon Load
  • 10 %
  • Endcapped
  • Double
  • Guard Column
  • No
  • Hardware
  • Cartridge
  • LC Platform
  • HPLC
  • Maximum Temperature
  • 40 °C at pH 6-9 60 °C at pH 2-6 40 °C at pH 6-960 °C at pH 2-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 3.5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-9
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Methanol/Water
AGIL7995118-504 ZORBAX RR Eclipse XDB-C18, 80Å, 5 µm, 4.0 x 4 mm, guard cartridge (AC), 10/pk, use with cartridge hardware PN 5021-1845 322 
Add to Cart
  • Inner Diameter (ID)
  • 4 mm
  • Length
  • 4 mm
  • Phase
  • Eclipse XDB-C18
  • UNSPSC Code
  • 41115711
  • USP Designation
  • L1
  • Brand
  • ZORBAX
  • Carbon Load
  • 10 %
  • Endcapped
  • Double
  • Guard Column
  • No
  • Hardware
  • Cartridge
  • LC Platform
  • HPLC
  • Maximum Temperature
  • 40 °C at pH 6-9 60 °C at pH 2-6 40 °C at pH 6-960 °C at pH 2-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-9
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Methanol/Water
AGIL7995118-585 ZORBAX RR Eclipse XDB-C18, 80Å, 5 µm, 4.6 x 250 mm, cartridge (AC), use with cartridge hardware PN 5021-1845 644 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 250 mm
  • Phase
  • Eclipse XDB-C18
  • UNSPSC Code
  • 41115709
  • USP Designation
  • L1
  • Brand
  • ZORBAX
  • Carbon Load
  • 10 %
  • Endcapped
  • Double
  • Guard Column
  • No
  • Hardware
  • Cartridge
  • LC Platform
  • HPLC
  • Maximum Temperature
  • 40 °C at pH 6-9 60 °C at pH 2-6 40 °C at pH 6-960 °C at pH 2-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-9
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Methanol/Water
AGIL7995208-344 ZORBAX RR StableBond C8, 4.6 x 75 mm, 3.5 µm, cartridge (AC). Use with cartridge hardware 5021-1845. 628 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 75 mm
  • Phase
  • SB-C8
  • UNSPSC Code
  • 41115709
  • Brand
  • ZORBAX
  • Carbon Load
  • 5.5 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Cartridge
  • LC Platform
  • HPLC
  • Maximum Temperature
  • 40 °C at pH 6-8 80 °C at pH 1-6 40 °C at pH 6-880 °C at pH 1-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 3.5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Methanol/Water
AGIL7995208-585 ZORBAX StableBond C8, 4.6 x 250 mm, 5 µm, 400 bar, cartridge (AC). Use with cartridge hardware 5021-1845. 638 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 250 mm
  • Phase
  • SB-C8
  • UNSPSC Code
  • 41115709
  • Brand
  • ZORBAX
  • Carbon Load
  • 5.5 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Cartridge
  • LC Platform
  • HPLC
  • Maximum Temperature
  • 40 °C at pH 6-8 80 °C at pH 1-6 40 °C at pH 6-880 °C at pH 1-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
AGIL7995208-595 ZORBAX StableBond C8, 4.6 x 150 mm, 5 µm, 400 bar, cartridge (AC). Use with cartridge hardware 5021-1845. 564 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 150 mm
  • Phase
  • SB-C8
  • UNSPSC Code
  • 41115709
  • Brand
  • ZORBAX
  • Carbon Load
  • 5.5 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Cartridge
  • LC Platform
  • HPLC
  • Maximum Temperature
  • 40 °C at pH 6-8 80 °C at pH 1-6 40 °C at pH 6-880 °C at pH 1-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
AGIL7995218-344 ZORBAX RR StableBond C18, 4.6 x 75 mm, 3.5 µm, cartridge (AC). Use with cartridge hardware 5021-1845. 628 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 75 mm
  • Phase
  • SB-C18
  • UNSPSC Code
  • 41115709
  • USP Designation
  • L1
  • Brand
  • ZORBAX
  • Carbon Load
  • 10 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Cartridge
  • LC Platform
  • HPLC
  • Maximum Temperature
  • 40 °C at pH 6-8 90 °C at pH 1-6 40 °C at pH 6-890 °C at pH 1-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 3.5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 0.8-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
AGIL7995218-585 ZORBAX StableBond C18, 4.6 x 250 mm, 5 µm, 400 bar, cartridge (AC). Use with cartridge hardware 5021-1845. 638 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 250 mm
  • Phase
  • SB-C18
  • UNSPSC Code
  • 41115709
  • USP Designation
  • L1
  • Brand
  • ZORBAX
  • Carbon Load
  • 10 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Cartridge
  • LC Platform
  • HPLC
  • Maximum Temperature
  • 40 °C at pH 6-8 90 °C at pH 1-6 40 °C at pH 6-890 °C at pH 1-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 0.8-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
AGIL7995218-595 ZORBAX StableBond C18, 4.6 x 150 mm, 5 µm, 400 bar, cartridge (AC). Use with cartridge hardware 5021-1845. 564 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 150 mm
  • Phase
  • SB-C18
  • UNSPSC Code
  • 41115709
  • USP Designation
  • L1
  • Brand
  • ZORBAX
  • Carbon Load
  • 10 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Cartridge
  • LC Platform
  • HPLC
  • Maximum Temperature
  • 40 °C at pH 6-8 90 °C at pH 1-6 40 °C at pH 6-890 °C at pH 1-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 0.8-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
AGIL820212-920 ZORBAX StableBond C18, 15.8 x 10 mm guard cartridge (PrepHT), 5 µm, 2/pk. Use with end-fitting 820444-901, or standalone hardware kit 420420-901. 341 
Add to Cart
  • Inner Diameter (ID)
  • 16 mm
  • Length
  • 8 mm
  • Phase
  • SB-C18
  • UNSPSC Code
  • 41115711
  • USP Designation
  • L1
  • Brand
  • ZORBAX
  • Carbon Load
  • 10 %
  • Endcapped
  • No
  • Guard Column
  • Yes
  • Hardware
  • Cartridge
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 40 °C at pH 6-8 90 °C at pH 1-6 40 °C at pH 6-890 °C at pH 1-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 0.8-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 340 bar
  • Separation Mode
  • Reversed Phase

Overview

The small molecule column portfolio includes state-of-the-art superficially porous InfinityLab Poroshell 120 columns as well as traditional fully porous ZORBAX, Polaris, and Pursuit columns.

When you choose Agilent small molecule LC columns, you get more than just a dependable product. You also get unmatched technical support from the world’s largest chromatography supplier.


Agilent gel permeation chromatography (GPC) and size exclusion chromatography (SEC) columns and standards have been the top-selling in the polymer industry for over 40 years. GPC and SEC is used to determine the molecular weight and size distribution of macromolecules. SEC and GPC columns generate accurate, reliable data for critical polymer parameters, including dispersity (PDI), molecular weight mass average (Mw), number average (Mn), and z-average (Mz).


The importance of understanding the attributes of a biologic drug, and the processes used to create it, cannot be underestimated.  Agilent AdvanceBio LC columns are designed and produced to provide results you can be sure of when analyzing highly complex biotherapeutic molecules and monitoring their purity, potency, and other critical quality attributes.



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