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Agilent offers the largest, most modern liquid chromatography (LC) column portfolios for small molecule analysis, with columns suitable for nearly all separation modes and applications.


Whether you are performing conventional or ultra-fast chromatography, separating biomolecules, or analyzing complex compounds, the industry’s highest-performing compounds deliver fast, reproducible results – all engineered with unparalleled quality and reliability.

Catalog No. Product Net Price
AGIL5064-8259 ZORBAX 300SB-C18 3.5µm, 0.3 x 100 mm. A reversed-phase C18 HPLC column with fully porous ZORBAX particles. StableBond technology ensures stability at low pH. 612 
Add to Cart
  • Inner Diameter (ID)
  • 0.3 mm
  • Length
  • 100 mm
  • Phase
  • 300SB-C18
  • UNSPSC Code
  • 41115709
  • Brand
  • ZORBAX 300SB-C18
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 90 °C
  • Part Number Application
  • Monoclonal Antibodies (mABs) PeptidesProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 3.5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-8
  • Pore Size
  • 300 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC LC & LC/MS
AGIL5064-8268 ZORBAX 300SB-C18 3.5µm, 0.5 x 150 mm. A reversed-phase C18 HPLC column with fully porous ZORBAX particles. StableBond technology ensures stability at low pH. 706 
Add to Cart
  • Inner Diameter (ID)
  • 0.5 mm
  • Length
  • 150 mm
  • Phase
  • 300SB-C18
  • UNSPSC Code
  • 41115709
  • Brand
  • ZORBAX 300SB-C18
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 90 °C
  • Part Number Application
  • Monoclonal Antibodies (mABs) PeptidesProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 3.5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-8
  • Pore Size
  • 300 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC LC & LC/MS
AGIL5064-8268 ZORBAX 300SB-C18 3.5µm, 0.5 x 150 mm. A reversed-phase C18 HPLC column with fully porous ZORBAX particles. StableBond technology ensures stability at low pH. 706 
Add to Cart
  • Inner Diameter (ID)
  • 0.5 mm
  • Length
  • 150 mm
  • Phase
  • 300SB-C18
  • UNSPSC Code
  • 41115709
  • Brand
  • ZORBAX 300SB-C18
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 90 °C
  • Part Number Application
  • Monoclonal Antibodies (mABs) PeptidesProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 3.5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-8
  • Pore Size
  • 300 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC LC & LC/MS
AGIL820212-918 ZORBAX StableBond 300 C8, 15.8 x 10 mm, 5 µm, guard cartridge (PrepHT) 2/pk. 300 Å pore size. Requires guard cartridge hardware kit, p/n 820999-901. 361 
Add to Cart
  • Inner Diameter (ID)
  • 17 mm
  • Length
  • 8 mm
  • Phase
  • 300SB-C8
  • UNSPSC Code
  • 41115711
  • Brand
  • ZORBAX
  • Guard Column
  • Yes
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 80 °C
  • Part Number Application
  • Monoclonal Antibodies (mABs) PeptidesProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-8
  • Pore Size
  • 300 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC LC & LC/MS
AGIL820675-124 ZORBAX StableBond 300 C3, 9.4 x 15 mm, 7 µm, guard cartridge (P) 2/pk 233 
Add to Cart
  • Inner Diameter (ID)
  • 9.4 mm
  • Length
  • 15 mm
  • Phase
  • 300SB-C3
  • UNSPSC Code
  • 41115711
  • Brand
  • ZORBAX
  • Guard Column
  • Yes
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 80 °C
  • Part Number Application
  • Monoclonal Antibodies (mABs) PeptidesProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 7 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-8
  • Pore Size
  • 300 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC LC & LC/MS
AGIL820950-918 ZORBAX StableBond 300 C8, 4.6 x 12.5 mm, 5 µm, guard cartridge (ZGC) 4/pk. 300 Å pore size. Requires guard cartridge hardware kit, p/n 820999-901. 218 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 13 mm
  • Phase
  • 300SB-C8
  • UNSPSC Code
  • 41115711
  • Brand
  • ZORBAX
  • Guard Column
  • Yes
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 80 °C
  • Part Number Application
  • Monoclonal Antibodies (mABs) PeptidesProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-8
  • Pore Size
  • 300 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC LC & LC/MS
AGIL820950-918 ZORBAX StableBond 300 C8, 4.6 x 12.5 mm, 5 µm, guard cartridge (ZGC) 4/pk. 300 Å pore size. Requires guard cartridge hardware kit, p/n 820999-901. 218 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 13 mm
  • Phase
  • 300SB-C8
  • UNSPSC Code
  • 41115711
  • Brand
  • ZORBAX
  • Guard Column
  • Yes
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 80 °C
  • Part Number Application
  • Monoclonal Antibodies (mABs) PeptidesProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-8
  • Pore Size
  • 300 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC LC & LC/MS
AGIL820950-921 ZORBAX StableBond 300 C18, 4.6 x 12.5 mm, 5 µm, guard cartridge (ZGC) 4/pk. 300 Å pore size. Use with hardware kit 820999-901. 218 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 13 mm
  • Phase
  • 300SB-C18
  • UNSPSC Code
  • 41115711
  • Brand
  • ZORBAX
  • Guard Column
  • Yes
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 90 °C
  • Part Number Application
  • Monoclonal Antibodies (mABs) PeptidesProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-8
  • Pore Size
  • 300 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC LC & LC/MS
AGIL820950-921 ZORBAX StableBond 300 C18, 4.6 x 12.5 mm, 5 µm, guard cartridge (ZGC) 4/pk. 300 Å pore size. Use with hardware kit 820999-901. 218 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 13 mm
  • Phase
  • 300SB-C18
  • UNSPSC Code
  • 41115711
  • Brand
  • ZORBAX
  • Guard Column
  • Yes
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 90 °C
  • Part Number Application
  • Monoclonal Antibodies (mABs) PeptidesProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-8
  • Pore Size
  • 300 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC LC & LC/MS
AGIL820950-923 ZORBAX StableBond 300 CN, 4.6 x 12.5 mm, 5 µm, guard cartridge (ZGC) 4/pk. 300 Å pore size. Requires guard cartridge hardware kit, p/n 820999-901. 218 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 13 mm
  • Phase
  • 300SB-CN
  • UNSPSC Code
  • 41115711
  • Brand
  • ZORBAX
  • Guard Column
  • Yes
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 80 °C
  • Part Number Application
  • Monoclonal Antibodies (mABs) PeptidesProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-8
  • Pore Size
  • 300 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC LC & LC/MS

Overview

The small molecule column portfolio includes state-of-the-art superficially porous InfinityLab Poroshell 120 columns as well as traditional fully porous ZORBAX, Polaris, and Pursuit columns.

When you choose Agilent small molecule LC columns, you get more than just a dependable product. You also get unmatched technical support from the world’s largest chromatography supplier.


Agilent gel permeation chromatography (GPC) and size exclusion chromatography (SEC) columns and standards have been the top-selling in the polymer industry for over 40 years. GPC and SEC is used to determine the molecular weight and size distribution of macromolecules. SEC and GPC columns generate accurate, reliable data for critical polymer parameters, including dispersity (PDI), molecular weight mass average (Mw), number average (Mn), and z-average (Mz).


The importance of understanding the attributes of a biologic drug, and the processes used to create it, cannot be underestimated.  Agilent AdvanceBio LC columns are designed and produced to provide results you can be sure of when analyzing highly complex biotherapeutic molecules and monitoring their purity, potency, and other critical quality attributes.



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