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Agilent offers the largest, most modern liquid chromatography (LC) column portfolios for small molecule analysis, with columns suitable for nearly all separation modes and applications.


Whether you are performing conventional or ultra-fast chromatography, separating biomolecules, or analyzing complex compounds, the industry’s highest-performing compounds deliver fast, reproducible results – all engineered with unparalleled quality and reliability.

Catalog No. Product Net Price
AGIL966967-906 ZORBAX RR Eclipse XDB-C8, 80Å, 4.6 x 75 mm, 3.5 µm 609 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 75 mm
  • Phase
  • Eclipse XDB-C8
  • UNSPSC Code
  • 41115709
  • USP Designation
  • L7
  • Brand
  • ZORBAX
  • Carbon Load
  • 7.6 %
  • Endcapped
  • Double
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC
  • Maximum Temperature
  • 40 °C at pH 6-9 60 °C at pH 2-6 40 °C at pH 6-960 °C at pH 2-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 3.5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-9
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
AGIL966967-912 ZORBAX RR Eclipse XDB-Phenyl, 80Å, 4.6 x 75 mm, 3.5 µm 609 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 75 mm
  • Phase
  • Eclipse XDB-Phenyl
  • UNSPSC Code
  • 41115711
  • USP Designation
  • L11
  • Brand
  • ZORBAX
  • Carbon Load
  • 7.2 %
  • Endcapped
  • Double
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC
  • Maximum Temperature
  • 40 °C at pH 6-9 60 °C at pH 2-6 40 °C at pH 6-960 °C at pH 2-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 3.5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-9
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
AGIL971700-902 ZORBAX RR Eclipse XDB-C18, 80Å, 2.1 x 50 mm, 3.5 µm 526 
Add to Cart
  • Inner Diameter (ID)
  • 2.1 mm
  • Length
  • 50 mm
  • Phase
  • Eclipse XDB-C18
  • UNSPSC Code
  • 41115709
  • USP Designation
  • L1
  • Brand
  • ZORBAX
  • Carbon Load
  • 10 %
  • Endcapped
  • Double
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC
  • Maximum Temperature
  • 40 °C at pH 6-9 60 °C at pH 2-6 40 °C at pH 6-960 °C at pH 2-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 3.5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-9
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
AGIL971700-906 ZORBAX RR Eclipse XDB-C8, 80Å, 2.1 x 50 mm, 3.5 µm 526 
Add to Cart
  • Inner Diameter (ID)
  • 2.1 mm
  • Length
  • 50 mm
  • Phase
  • Eclipse XDB-C8
  • UNSPSC Code
  • 41115709
  • USP Designation
  • L7
  • Brand
  • ZORBAX
  • Carbon Load
  • 7.6 %
  • Endcapped
  • Double
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC
  • Maximum Temperature
  • 40 °C at pH 6-9 60 °C at pH 2-6 40 °C at pH 6-960 °C at pH 2-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 3.5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-9
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
AGIL972700-902 ZORBAX RR Eclipse XDB-C18, 80Å, 2.1 x 20 mm, 3.5 µm, 600 bar pressure limit 383 
Add to Cart
  • Inner Diameter (ID)
  • 2.1 mm
  • Length
  • 20 mm
  • Phase
  • Eclipse XDB-C18
  • UNSPSC Code
  • 41115709
  • USP Designation
  • L1
  • Brand
  • ZORBAX
  • Carbon Load
  • 10 %
  • Endcapped
  • Double
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC
  • Maximum Temperature
  • 40 °C at pH 6-9 60 °C at pH 2-6 40 °C at pH 6-960 °C at pH 2-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 3.5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-9
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 600 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Methanol/Water
AGIL973700-932 ZORBAX RR Eclipse XDB-C1, 80Å, 3.5 µm, 2.1 x 30 mm, cartridge (RR), 3/pk, use with cartridge hardware 820555-901 844 
Add to Cart
  • Inner Diameter (ID)
  • 2.1 mm
  • Length
  • 30 mm
  • Phase
  • Eclipse XDB-C18
  • UNSPSC Code
  • 41115709
  • USP Designation
  • L1
  • Brand
  • ZORBAX
  • Carbon Load
  • 10 %
  • Endcapped
  • Double
  • Guard Column
  • No
  • Hardware
  • Cartridge
  • LC Platform
  • HPLC
  • Maximum Temperature
  • 40 °C at pH 6-9 60 °C at pH 2-6 40 °C at pH 6-960 °C at pH 2-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 3.5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-9
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Methanol/Water
AGIL974700-902 ZORBAX RR Eclipse XDB-C18, 80Å, 2.1 x 30 mm, 3.5 µm, 600 bar pressure limit 456 
Add to Cart
  • Inner Diameter (ID)
  • 2.1 mm
  • Length
  • 30 mm
  • Phase
  • Eclipse XDB-C18
  • UNSPSC Code
  • 41115709
  • USP Designation
  • L1
  • Brand
  • ZORBAX
  • Carbon Load
  • 10 %
  • Endcapped
  • Double
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC
  • Maximum Temperature
  • 40 °C at pH 6-9 60 °C at pH 2-6 40 °C at pH 6-960 °C at pH 2-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 3.5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-9
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 600 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Methanol/Water
AGIL975700-932 ZORBAX RR Eclipse XDB-C1, 80Å, 3.5 µm, 2.1 x 15 mm, cartridge (RR), 3/pk, use with cartridge hardware 820555-901 622 
Add to Cart
  • Inner Diameter (ID)
  • 2.1 mm
  • Length
  • 15 mm
  • Phase
  • Eclipse XDB-C18
  • UNSPSC Code
  • 41115709
  • USP Designation
  • L1
  • Brand
  • ZORBAX
  • Carbon Load
  • 10 %
  • Endcapped
  • Double
  • Guard Column
  • No
  • Hardware
  • Cartridge
  • LC Platform
  • HPLC
  • Maximum Temperature
  • 40 °C at pH 6-9 60 °C at pH 2-6 40 °C at pH 6-960 °C at pH 2-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 3.5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-9
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Methanol/Water
AGIL975700-936 ZORBAX RR Eclipse XDB-C8, 80Å, 2.1 x 15 mm, 3.5 µm, cartridge (RR) 3/pk, use with cartridge hardware 820555-901 622 
Add to Cart
  • Inner Diameter (ID)
  • 2.1 mm
  • Length
  • 15 mm
  • Phase
  • Eclipse XDB-C8
  • UNSPSC Code
  • 41115709
  • USP Designation
  • L7
  • Brand
  • ZORBAX
  • Carbon Load
  • 7.6 %
  • Endcapped
  • Double
  • Guard Column
  • No
  • Hardware
  • Cartridge
  • LC Platform
  • HPLC
  • Maximum Temperature
  • 40 °C at pH 6-9 60 °C at pH 2-6 40 °C at pH 6-960 °C at pH 2-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 3.5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-9
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
AGIL981757-302 ZORBAX RRHD Eclipse XDB-C18, 80Å, 3.0 x 50 mm, 1.8 µm, 1200 bar pressure limit 723 
Add to Cart
  • Inner Diameter (ID)
  • 3 mm
  • Length
  • 50 mm
  • Phase
  • Eclipse XDB-C18
  • UNSPSC Code
  • 41115709
  • USP Designation
  • L1
  • Brand
  • ZORBAX
  • Carbon Load
  • 10 %
  • Endcapped
  • Double
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC UHPLC Low Dispersion U
  • Maximum Temperature
  • 40 °C at pH 6-9 60 °C at pH 2-6 40 °C at pH 6-960 °C at pH 2-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 1.8 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-9
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 1200 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water

Overview

The small molecule column portfolio includes state-of-the-art superficially porous InfinityLab Poroshell 120 columns as well as traditional fully porous ZORBAX, Polaris, and Pursuit columns.

When you choose Agilent small molecule LC columns, you get more than just a dependable product. You also get unmatched technical support from the world’s largest chromatography supplier.


Agilent gel permeation chromatography (GPC) and size exclusion chromatography (SEC) columns and standards have been the top-selling in the polymer industry for over 40 years. GPC and SEC is used to determine the molecular weight and size distribution of macromolecules. SEC and GPC columns generate accurate, reliable data for critical polymer parameters, including dispersity (PDI), molecular weight mass average (Mw), number average (Mn), and z-average (Mz).


The importance of understanding the attributes of a biologic drug, and the processes used to create it, cannot be underestimated.  Agilent AdvanceBio LC columns are designed and produced to provide results you can be sure of when analyzing highly complex biotherapeutic molecules and monitoring their purity, potency, and other critical quality attributes.



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