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Agilent offers the largest, most modern liquid chromatography (LC) column portfolios for small molecule analysis, with columns suitable for nearly all separation modes and applications.


Whether you are performing conventional or ultra-fast chromatography, separating biomolecules, or analyzing complex compounds, the industry’s highest-performing compounds deliver fast, reproducible results – all engineered with unparalleled quality and reliability.

Catalog No. Product Net Price
AGIL5190-1435 ZORBAX Selectivity Method Development Kit, 4.6 x 100 mm, 3.5 µm; includes ZORBAX Eclipse Plus C18, Bonus RP, and Eclipse Plus Phenyl-Hexyl columns 1484 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 100 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • ZORBAX
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 3.5 µm
  • Particle Type
  • Fully Porous
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
AGIL5190-6152 ZORBAX RRHD pH Method Development Kit, 2.1 x 50 mm, 1.8 µm, 1200 bar pressure limit; includes StableBond SB-C18, Eclipse Plus C18, and Extend-C18 columns 1659 
Add to Cart
  • Inner Diameter (ID)
  • 2.1 mm
  • Length
  • 50 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • ZORBAX
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • UHPLC
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 1.8 µm
  • Particle Type
  • Fully Porous
  • Pressure Rating
  • 1200 bar
  • Separation Mode
  • Reversed Phase
AGIL5190-6153 ZORBAX RRHD Eclipse Plus Method Development Kit, 2.1 x 50 mm, 1.8 µm, 1200 bar pressure limit; includes Eclipse Plus C18, Eclipse Plus C8, Eclipse Plus Phenyl-Hexyl columns 1659 
Add to Cart
  • Inner Diameter (ID)
  • 2.1 mm
  • Length
  • 50 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • ZORBAX
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC UHPLC Low Dispersion U
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 1.8 µm
  • Particle Type
  • Fully Porous
  • Pore Size
  • 95 Å
  • Pressure Rating
  • 1200 bar
  • Separation Mode
  • Reversed Phase
AGIL5190-6154 ZORBAX RRHD Aqueous Method Development Kit, includes SB-Aq, Bonus-RP, and Eclipse Plus Phenyl-Hexyl columns, 2.1 x 50 mm, 1.8 µm, 1200 bar pressure limit 1659 
Add to Cart
  • Inner Diameter (ID)
  • 2.1 mm
  • Length
  • 50 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • ZORBAX
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC UHPLC
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 1.8 µm
  • Particle Type
  • Fully Porous
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 1200 bar
  • Separation Mode
  • Reversed Phase
AGIL5190-6155 InfinityLab Poroshell 120 Selectivity Method Development Kit, includes Poroshell 120 EC-C18, Phenyl-Hexyl, Bonus-RP columns, 2.1 x 50 mm 1364 
Add to Cart
  • Inner Diameter (ID)
  • 2.1 mm
  • Length
  • 50 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • InfinityLab Poroshell 120
  • Endcapped
  • Yes
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC UHPLC
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 2.7 µm
  • Particle Type
  • Superficially Porous
  • Pore Size
  • 120 Å
  • Pressure Rating
  • 600 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
AGIL5190-6156 InfinityLab Poroshell 120 Selectivity Method Development Kit, includes Poroshell 120 EC-C18, Phenyl-Hexyl, Bonus-RP columns, 4.6 x 50 mm, 2.7 µm 1364 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 50 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • InfinityLab Poroshell 120
  • Endcapped
  • Yes
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC UHPLC
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 2.7 µm
  • Particle Type
  • Superficially Porous
  • Pore Size
  • 120 Å
  • Pressure Rating
  • 600 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
AGIL5190-6157 InfinityLab Poroshell 120 Aqueous Method Development Kit, 2.1 x 50 mm, 2.7 µm, 3/pk. includes Poroshell 120 SB-Aq, Phenyl-Hexyl and Bonus-RP columns. 1364 
Add to Cart
  • Inner Diameter (ID)
  • 2.1 mm
  • Length
  • 50 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • InfinityLab Poroshell 120
  • Endcapped
  • Yes
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC UHPLC
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 2.7 µm
  • Particle Type
  • Superficially Porous
  • Pore Size
  • 120 Å
  • Pressure Rating
  • 600 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
AGIL5190-6158 InfinityLab Poroshell 120 Aqueous Method Development Kit, includes Poroshell 120 SB-Aq, Phenyl-Hexyl, and Bonus-RP columns, 4.6 x 50 mm, 2.7 µm 1364 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 50 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • InfinityLab Poroshell 120
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • UHPLC
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 2.7 µm
  • Particle Type
  • Superficially Porous
  • Pore Size
  • 120 Å
  • Pressure Rating
  • 600 bar
  • Separation Mode
  • Reversed Phase
AGIL5190-6159 InfinityLab Poroshell 120 L1, L7, and L10 USP Method Development Kit, includes Poroshell 120 EC-C18, EC-C8, EC-CN columns, 4.6 x 100 mm, 2.7 µm 1669 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 100 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • InfinityLab Poroshell 120
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC UHPLC
  • Maximum Temperature
  • 60 °C
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 2.7 µm
  • Particle Type
  • Superficially Porous
  • Pore Size
  • 120 Å
  • Pressure Rating
  • 600 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
AGIL5190-2511K Agilent Bio SEC-3, 300Å, 7.8, 300 mm, MVK 3/pk. A size exclusion column for aggregate analysis of peptides and small proteins. Resolving range 5-1,250 kDa. This method validation kit contains 3 columns, each from a different lot. 7904 
Add to Cart
  • Inner Diameter (ID)
  • 7.8 mm
  • Length
  • 300 mm
  • Phase
  • SEC
  • UNSPSC Code
  • 41115709
  • Brand
  • Agilent Bio SEC-3
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 80 °C
  • Molecular Weight Lower Limit
  • 5000 Da
  • Part Number Application
  • Aggregate & Fragment AnalysisMonoclonal Antibodies (mABs)PeptidesProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-8.5
  • Pore Size
  • 300 Å
  • Pressure Rating
  • 240 bar
  • Separation Mode
  • Size Exclusion (SEC)
  • Shipping Solvent
  • Phosphate Buffer
  • Technique
  • LC

Overview

The small molecule column portfolio includes state-of-the-art superficially porous InfinityLab Poroshell 120 columns as well as traditional fully porous ZORBAX, Polaris, and Pursuit columns.

When you choose Agilent small molecule LC columns, you get more than just a dependable product. You also get unmatched technical support from the world’s largest chromatography supplier.


Agilent gel permeation chromatography (GPC) and size exclusion chromatography (SEC) columns and standards have been the top-selling in the polymer industry for over 40 years. GPC and SEC is used to determine the molecular weight and size distribution of macromolecules. SEC and GPC columns generate accurate, reliable data for critical polymer parameters, including dispersity (PDI), molecular weight mass average (Mw), number average (Mn), and z-average (Mz).


The importance of understanding the attributes of a biologic drug, and the processes used to create it, cannot be underestimated.  Agilent AdvanceBio LC columns are designed and produced to provide results you can be sure of when analyzing highly complex biotherapeutic molecules and monitoring their purity, potency, and other critical quality attributes.



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