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Agilent offers the largest, most modern liquid chromatography (LC) column portfolios for small molecule analysis, with columns suitable for nearly all separation modes and applications.


Whether you are performing conventional or ultra-fast chromatography, separating biomolecules, or analyzing complex compounds, the industry’s highest-performing compounds deliver fast, reproducible results – all engineered with unparalleled quality and reliability.

Catalog No. Product Net Price
AGIL575250-902 InfinityLab ZORBAX Eclipse Plus C18, 30 x 250 mm, 5 µm. reversed phase high performance liquid chromatography (HPLC) columns provide seamless scale-up between analytical and preparative columns. 9666 
Add to Cart
  • Inner Diameter (ID)
  • 30 mm
  • Length
  • 250 mm
  • Phase
  • Eclipse Plus C18
  • USP Designation
  • L1
  • Brand
  • ZORBAX
  • Carbon Load
  • 9 %
  • Endcapped
  • Double
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 40 °C at pH 6-9 60 °C at pH 2-6 40 °C at pH 6-960 °C at pH 2-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-9
  • Pore Size
  • 95 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
AGIL575250-906 InfinityLab ZORBAX Eclipse Plus C8, 30 x 250 mm, 5 µm. reversed phase high performance liquid chromatography (HPLC) columns provide seamless scale-up between analytical and preparative columns. 9666 
Add to Cart
  • Inner Diameter (ID)
  • 30 mm
  • Length
  • 250 mm
  • Phase
  • Eclipse Plus C8
  • USP Designation
  • L7
  • Brand
  • ZORBAX
  • Carbon Load
  • 7 %
  • Endcapped
  • Double
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 40 °C at pH 6-9 60 °C at pH 2-6 40 °C at pH 6-960 °C at pH 2-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-9
  • Pore Size
  • 95 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
AGIL585050-902 InfinityLab ZORBAX SB-C18, 21.2 x 50 mm, 5 µm. Preparative LC column 1804 
Add to Cart
  • Inner Diameter (ID)
  • 21.2 mm
  • Length
  • 50 mm
  • Phase
  • SB-C18
  • USP Designation
  • L1
  • Brand
  • ZORBAX
  • Carbon Load
  • 10 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 40 °C at pH 6-8 90 °C at pH 1-6 40 °C at pH 6-890 °C at pH 1-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
AGIL585100-902 InfinityLab ZORBAX SB-C18, 21.2 x 100 mm, 5 µm. Preparative LC column 2606 
Add to Cart
  • Inner Diameter (ID)
  • 21.2 mm
  • Length
  • 100 mm
  • Phase
  • SB-C18
  • USP Designation
  • L1
  • Brand
  • ZORBAX
  • Carbon Load
  • 10 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 40 °C at pH 6-8 90 °C at pH 1-6 40 °C at pH 6-890 °C at pH 1-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
AGIL585100-906 InfinityLab ZORBAX SB-C8, 21.2 x 100 mm, 5 µm. Preparative LC column 2607 
Add to Cart
  • Inner Diameter (ID)
  • 21.2 mm
  • Length
  • 100 mm
  • Phase
  • SB-C8
  • Brand
  • ZORBAX
  • Carbon Load
  • 5.5 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 40 °C at pH 6-8 80 °C at pH 1-6 40 °C at pH 6-880 °C at pH 1-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
AGIL585150-902 InfinityLab ZORBAX SB-C18, 21.2 x 150 mm, 5 µm. Preparative LC column 3006 
Add to Cart
  • Inner Diameter (ID)
  • 21.2 mm
  • Length
  • 150 mm
  • Phase
  • SB-C18
  • USP Designation
  • L1
  • Brand
  • ZORBAX
  • Carbon Load
  • 10 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 40 °C at pH 6-8 90 °C at pH 1-6 40 °C at pH 6-890 °C at pH 1-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
AGIL585250-902 InfinityLab ZORBAX SB-C18, 21.2 x 250 mm, 5 µm. Preparative LC column 3558 
Add to Cart
  • Inner Diameter (ID)
  • 21.2 mm
  • Length
  • 250 mm
  • Phase
  • SB-C18
  • USP Designation
  • L1
  • Brand
  • ZORBAX
  • Carbon Load
  • 10 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 40 °C at pH 6-8 90 °C at pH 1-6 40 °C at pH 6-890 °C at pH 1-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
AGIL595050-902 InfinityLab ZORBAX Eclipse Plus C18, 21.2 x 50 mm, 5 µm. Preparative LC column 1804 
Add to Cart
  • Inner Diameter (ID)
  • 21.2 mm
  • Length
  • 50 mm
  • Phase
  • Eclipse Plus C18
  • USP Designation
  • L1
  • Brand
  • ZORBAX
  • Carbon Load
  • 9 %
  • Endcapped
  • Double
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 40 °C at pH 6-9 60 °C at pH 2-6 40 °C at pH 6-960 °C at pH 2-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-9
  • Pore Size
  • 95 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
AGIL595050-906 InfinityLab ZORBAX Eclipse Plus C8, 21.2 x 50 mm, 5 µm. Preparative LC column 1804 
Add to Cart
  • Inner Diameter (ID)
  • 21.2 mm
  • Length
  • 50 mm
  • Phase
  • Eclipse Plus C8
  • Brand
  • ZORBAX
  • Carbon Load
  • 7 %
  • Endcapped
  • Double
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 40 °C at pH 6-9 60 °C at pH 2-6 40 °C at pH 6-960 °C at pH 2-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-9
  • Pore Size
  • 95 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
AGIL595050-912 InfinityLab ZORBAX Eclipse Plus Phenyl-Hexyl, 21.2 x 50 mm, 5 µm. Preparative LC column 1804 
Add to Cart
  • Inner Diameter (ID)
  • 21.2 mm
  • Length
  • 50 mm
  • Phase
  • Eclipse Plus Phenyl-Hexyl
  • Brand
  • ZORBAX
  • Carbon Load
  • 9 %
  • Endcapped
  • Double
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 40 °C at pH 6-9 60 °C at pH 2-6 40 °C at pH 6-860 °C at pH 2-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-8
  • Pore Size
  • 95 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water

Overview

The small molecule column portfolio includes state-of-the-art superficially porous InfinityLab Poroshell 120 columns as well as traditional fully porous ZORBAX, Polaris, and Pursuit columns.

When you choose Agilent small molecule LC columns, you get more than just a dependable product. You also get unmatched technical support from the world’s largest chromatography supplier.


Agilent gel permeation chromatography (GPC) and size exclusion chromatography (SEC) columns and standards have been the top-selling in the polymer industry for over 40 years. GPC and SEC is used to determine the molecular weight and size distribution of macromolecules. SEC and GPC columns generate accurate, reliable data for critical polymer parameters, including dispersity (PDI), molecular weight mass average (Mw), number average (Mn), and z-average (Mz).


The importance of understanding the attributes of a biologic drug, and the processes used to create it, cannot be underestimated.  Agilent AdvanceBio LC columns are designed and produced to provide results you can be sure of when analyzing highly complex biotherapeutic molecules and monitoring their purity, potency, and other critical quality attributes.



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