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Agilent offers the largest, most modern liquid chromatography (LC) column portfolios for small molecule analysis, with columns suitable for nearly all separation modes and applications.


Whether you are performing conventional or ultra-fast chromatography, separating biomolecules, or analyzing complex compounds, the industry’s highest-performing compounds deliver fast, reproducible results – all engineered with unparalleled quality and reliability.

Catalog No. Product Net Price
PL1212-6400 PLRP-S 100Å, 25 x 300 mm, 10-15 µm 3420 
Add to Cart
  • Inner Diameter (ID)
  • 25 mm
  • Length
  • 300 mm
  • Phase
  • DVB
  • UNSPSC Code
  • 41115711
  • Brand
  • PLRP-S
  • Hardware
  • SS
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 200 °C
  • Part Number Application
  • Peptides Preparative HPLC Columns & Bulk MediaProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 10 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-14
  • Pore Size
  • 100 Å
  • Pressure Rating
  • 103 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC LC & LC/MS
PL1212-6401 PLRP-S 300Å, 25 x 300 mm, 10-15 µm 3868 
Add to Cart
  • Inner Diameter (ID)
  • 25 mm
  • Length
  • 300 mm
  • Phase
  • DVB
  • UNSPSC Code
  • 41115711
  • Brand
  • PLRP-S
  • Hardware
  • SS
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 200 °C
  • Part Number Application
  • Peptides Preparative HPLC Columns & Bulk MediaProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 10 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-14
  • Pore Size
  • 300 Å
  • Pressure Rating
  • 103 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC LC & LC/MS
PL1212-6800 PLRP-S 100Å, 25 x 300 mm, 8 µm 3977 
Add to Cart
  • Inner Diameter (ID)
  • 25 mm
  • Length
  • 300 mm
  • Phase
  • DVB
  • UNSPSC Code
  • 41115711
  • Brand
  • PLRP-S
  • Hardware
  • SS
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 200 °C
  • Part Number Application
  • Peptides Preparative HPLC Columns & Bulk MediaProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 8 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-14
  • Pore Size
  • 100 Å
  • Pressure Rating
  • 207 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC LC & LC/MS
PL1312-1802 PLRP-S 1000Å, 1.0 x 50 mm, 8 µm 594 
Add to Cart
  • Inner Diameter (ID)
  • 1 mm
  • Length
  • 50 mm
  • Phase
  • DVB
  • UNSPSC Code
  • 41115711
  • Brand
  • PLRP-S
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 200 °C
  • Part Number Application
  • Aggregate & Fragment AnalysisMonoclonal Antibodies (mABs)PeptidesProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 8 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-14
  • Pore Size
  • 1000 Å
  • Pressure Rating
  • 207 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC LC & LC/MS
PL1312-3300 PLRP-S 100Å, 1.0 x 150 mm, 3 µm 659 
Add to Cart
  • Inner Diameter (ID)
  • 1 mm
  • Length
  • 150 mm
  • Phase
  • DVB
  • UNSPSC Code
  • 41115711
  • Brand
  • PLRP-S
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 200 °C
  • Part Number Application
  • Aggregate & Fragment AnalysisMonoclonal Antibodies (mABs)PeptidesProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 3 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-14
  • Pore Size
  • 100 Å
  • Pressure Rating
  • 275 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC LC & LC/MS
PL1512-1301 PLRP-S 300Å, 4.6 x 50 mm, 3 µm 582 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 50 mm
  • Phase
  • DVB
  • UNSPSC Code
  • 41115711
  • Brand
  • PLRP-S
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 200 °C
  • Part Number Application
  • Aggregate & Fragment AnalysisMonoclonal Antibodies (mABs)PeptidesProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 3 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-14
  • Pore Size
  • 300 Å
  • Pressure Rating
  • 275 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC LC & LC/MS
PL1512-1501 PLRP-S 300Å, 4.6 x 50 mm, 5 µm 684 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 50 mm
  • Phase
  • DVB
  • UNSPSC Code
  • 41115711
  • Brand
  • PLRP-S
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 200 °C
  • Part Number Application
  • Aggregate & Fragment AnalysisMonoclonal Antibodies (mABs)PeptidesProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-14
  • Pore Size
  • 300 Å
  • Pressure Rating
  • 207 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC LC & LC/MS
PL1512-1502 PLRP-S 1000Å, 4.6 x 50 mm, 5 µm 649 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 50 mm
  • Phase
  • DVB
  • UNSPSC Code
  • 41115711
  • Brand
  • PLRP-S
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 200 °C
  • Part Number Application
  • Aggregate & Fragment AnalysisMonoclonal Antibodies (mABs)PeptidesProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-14
  • Pore Size
  • 1000 Å
  • Pressure Rating
  • 207 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC LC & LC/MS
PL1512-1503 PLRP-S 4000Å, 4.6 x 50 mm, 5 µm 696 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 50 mm
  • Phase
  • DVB
  • UNSPSC Code
  • 41115711
  • Brand
  • PLRP-S
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 200 °C
  • Part Number Application
  • Aggregate & Fragment AnalysisMonoclonal Antibodies (mABs)PeptidesProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-14
  • Pore Size
  • 4000 Å
  • Pressure Rating
  • 207 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC LC & LC/MS
PL1512-1802 PLRP-S 1000Å, 4.6 x 50 mm, 8 µm 591 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 50 mm
  • Phase
  • DVB
  • UNSPSC Code
  • 41115711
  • Brand
  • PLRP-S
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 200 °C
  • Part Number Application
  • Aggregate & Fragment AnalysisMonoclonal Antibodies (mABs)PeptidesProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 8 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-14
  • Pore Size
  • 1000 Å
  • Pressure Rating
  • 207 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC LC & LC/MS

Overview

The small molecule column portfolio includes state-of-the-art superficially porous InfinityLab Poroshell 120 columns as well as traditional fully porous ZORBAX, Polaris, and Pursuit columns.

When you choose Agilent small molecule LC columns, you get more than just a dependable product. You also get unmatched technical support from the world’s largest chromatography supplier.


Agilent gel permeation chromatography (GPC) and size exclusion chromatography (SEC) columns and standards have been the top-selling in the polymer industry for over 40 years. GPC and SEC is used to determine the molecular weight and size distribution of macromolecules. SEC and GPC columns generate accurate, reliable data for critical polymer parameters, including dispersity (PDI), molecular weight mass average (Mw), number average (Mn), and z-average (Mz).


The importance of understanding the attributes of a biologic drug, and the processes used to create it, cannot be underestimated.  Agilent AdvanceBio LC columns are designed and produced to provide results you can be sure of when analyzing highly complex biotherapeutic molecules and monitoring their purity, potency, and other critical quality attributes.



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