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Agilent offers the largest, most modern liquid chromatography (LC) column portfolios for small molecule analysis, with columns suitable for nearly all separation modes and applications.


Whether you are performing conventional or ultra-fast chromatography, separating biomolecules, or analyzing complex compounds, the industry’s highest-performing compounds deliver fast, reproducible results – all engineered with unparalleled quality and reliability.

Catalog No. Product Net Price
PL1212-3201 PLRP-S 300Å, 25 x 150 mm, 15-20 µm 2764 
Add to Cart
  • Inner Diameter (ID)
  • 25 mm
  • Length
  • 150 mm
  • Phase
  • PLRP-S
  • UNSPSC Code
  • 41115711
  • Brand
  • PLRP-S
  • Hardware
  • SS
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 200 °C
  • Part Number Application
  • Intact & Subunit Analysis OligosPeptides
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 15 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-14
  • Pore Size
  • 300 Å
  • Pressure Rating
  • 103 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC & LC/MS
PL1212-3702 PLRP-S 1000Å, 25 x 150 mm, 30 µm 2837 
Add to Cart
  • Inner Diameter (ID)
  • 25 mm
  • Length
  • 150 mm
  • Phase
  • DVB
  • UNSPSC Code
  • 41115711
  • Brand
  • PLRP-S
  • Hardware
  • SS
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 200 °C
  • Part Number Application
  • Peptides Preparative HPLC Columns & Bulk MediaProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 30 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-14
  • Pore Size
  • 1000 Å
  • Pressure Rating
  • 103 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC LC & LC/MS
PL1212-3703 PLRP-S 4000Å, 25 x 150 mm, 30 µm 2837 
Add to Cart
  • Inner Diameter (ID)
  • 25 mm
  • Length
  • 150 mm
  • Phase
  • DVB
  • UNSPSC Code
  • 41115711
  • Brand
  • PLRP-S
  • Hardware
  • SS
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 200 °C
  • Part Number Application
  • Peptides Preparative HPLC Columns & Bulk MediaProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 30 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-14
  • Pore Size
  • 4000 Å
  • Pressure Rating
  • 103 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC LC & LC/MS
PL1212-3800 PLRP-S 100Å, 25 x 150 mm, 8 µm 2849 
Add to Cart
  • Inner Diameter (ID)
  • 25 mm
  • Length
  • 150 mm
  • Phase
  • DVB
  • UNSPSC Code
  • 41115711
  • Brand
  • PLRP-S
  • Hardware
  • SS
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 200 °C
  • Part Number Application
  • Peptides Preparative HPLC Columns & Bulk MediaProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 8 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-14
  • Pore Size
  • 100 Å
  • Pressure Rating
  • 207 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC LC & LC/MS
PL1212-3801 PLRP-S 300Å, 25 x 150 mm, 8 µm 3172 
Add to Cart
  • Inner Diameter (ID)
  • 25 mm
  • Length
  • 150 mm
  • Phase
  • DVB
  • UNSPSC Code
  • 41115711
  • Brand
  • PLRP-S
  • Hardware
  • SS
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 200 °C
  • Part Number Application
  • Peptides Preparative HPLC Columns & Bulk MediaProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 8 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-14
  • Pore Size
  • 300 Å
  • Pressure Rating
  • 207 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC LC & LC/MS
PL1212-4201 PLRP-S 300Å, 25 x 25 mm, 20 µm, guard 1331 
Add to Cart
  • Inner Diameter (ID)
  • 25 mm
  • Length
  • 25 mm
  • Phase
  • DVB
  • UNSPSC Code
  • 41115711
  • Brand
  • PLRP-S
  • Guard Column
  • Yes
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 200 °C
  • Part Number Application
  • Peptides Preparative HPLC Columns & Bulk MediaProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 20 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-14
  • Pore Size
  • 300 Å
  • Pressure Rating
  • 103 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC LC & LC/MS
PL1212-4800 PLRP-S 300Å, 25 x 25 mm, 8 µm, guard (1/16 in) 1331 
Add to Cart
  • Inner Diameter (ID)
  • 25 mm
  • Length
  • 25 mm
  • Phase
  • DVB
  • UNSPSC Code
  • 41115711
  • Brand
  • PLRP-S
  • Guard Column
  • Yes
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 200 °C
  • Part Number Application
  • Peptides Preparative HPLC Columns & Bulk MediaProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 8 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-14
  • Pore Size
  • 300 Å
  • Pressure Rating
  • 207 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC LC & LC/MS
PL1212-6100 PLRP-S 100Å, 25 x 300 mm, 10 µm 3793 
Add to Cart
  • Inner Diameter (ID)
  • 25 mm
  • Length
  • 300 mm
  • Phase
  • DVB
  • UNSPSC Code
  • 41115711
  • Brand
  • PLRP-S
  • Hardware
  • SS
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 200 °C
  • Part Number Application
  • Peptides Preparative HPLC Columns & Bulk MediaProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 10 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-14
  • Pore Size
  • 100 Å
  • Pressure Rating
  • 207 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC LC & LC/MS
PL1212-6101 PLRP-S 300Å, 25 x 300 mm, 10 µm 4548 
Add to Cart
  • Inner Diameter (ID)
  • 25 mm
  • Length
  • 300 mm
  • Phase
  • DVB
  • UNSPSC Code
  • 41115711
  • Brand
  • PLRP-S
  • Hardware
  • SS
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 200 °C
  • Part Number Application
  • Peptides Preparative HPLC Columns & Bulk MediaProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 10 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-14
  • Pore Size
  • 300 Å
  • Pressure Rating
  • 207 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC LC & LC/MS
PL1212-6201 PLRP-S 300Å, 25 x 300 mm, 15-20 µm 3630 
Add to Cart
  • Inner Diameter (ID)
  • 25 mm
  • Length
  • 300 mm
  • Phase
  • DVB
  • UNSPSC Code
  • 41115711
  • Brand
  • PLRP-S
  • Hardware
  • SS
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 200 °C
  • Part Number Application
  • Peptides Preparative HPLC Columns & Bulk MediaProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 20 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-14
  • Pore Size
  • 300 Å
  • Pressure Rating
  • 103 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC LC & LC/MS

Overview

The small molecule column portfolio includes state-of-the-art superficially porous InfinityLab Poroshell 120 columns as well as traditional fully porous ZORBAX, Polaris, and Pursuit columns.

When you choose Agilent small molecule LC columns, you get more than just a dependable product. You also get unmatched technical support from the world’s largest chromatography supplier.


Agilent gel permeation chromatography (GPC) and size exclusion chromatography (SEC) columns and standards have been the top-selling in the polymer industry for over 40 years. GPC and SEC is used to determine the molecular weight and size distribution of macromolecules. SEC and GPC columns generate accurate, reliable data for critical polymer parameters, including dispersity (PDI), molecular weight mass average (Mw), number average (Mn), and z-average (Mz).


The importance of understanding the attributes of a biologic drug, and the processes used to create it, cannot be underestimated.  Agilent AdvanceBio LC columns are designed and produced to provide results you can be sure of when analyzing highly complex biotherapeutic molecules and monitoring their purity, potency, and other critical quality attributes.



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