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Catalog No. MN720081.40
Part No. 720081.40
Supplier MACHEREY‑NAGEL
EC HPLC column (analytical), NUCLEOSIL CHIRAL-1, 5 µm, 250x4 mm
Net Price
Special offer
Availability

6 weeks

PROPERTIES
  • Recommended application(s)
    Chiral, enantiomers, Enantiomers with two polar functional groups, HPLC, Lactic acid, α-amino acids, α-hydroxycarboxylic acids
  • Storage temperature
    RT
  • Scope of delivery
    1x analytical HPLC column, instruction leaflet, certificate of analysis
  • Hazardous material
    No
  • Method
    HPLC, analytical
  • Brand
    NUCLEOSIL
  • Base material
    NUCLEOSIL - the standard silica
  • Phase
    NUCLEOSIL CHIRAL-1
  • USP listing
    L32
  • Surface chemistry
    L-hydroxyproline – Cu²⁺ complexes (chiral selector) modification
  • Mode
    Special application or diverse
  • Type
    EC HPLC column (analytical)
  • Hardware
    Stainless steel
  • Column length
    250 mm
  • Column inner diameter
    4 mm
  • Particle type
    Fully porous particles (FPP)
  • Particle shape
    Spherical
  • Particle size
    5 µm
  • Eluent in HPLC column
    0.5 mmol/L copper sulfate solution
  • Endcapped
    No
  • Carbon content
    Not available or proprietary
  • pH stability
    2.0–8.0
  • Pore size
    120 Å
  • Specific surface according to BET
    200 m²/g
  • Temperature stability (max)
    60 °C
  • Pressure stability (max)
    400 bar
  • Column volume
    3.15 mL
DESCRIPTION
Silica-based phase for HPLC enantiomer separation. Principal interaction mode - formation of ternary mixed-ligand complexes with Cu(II) ions. Differences in the stability of the diastereomeric complexes cause chromatographic separation. Based on the original NUCLEOSIL silica gel. It is one of the first spherical silicas for HPLC and was originally developed by MACHEREY-NAGEL in 1974. It is exclusively manufactured in Germany and is still one of the most used HPLC silicas in quality control around the globe.
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