DESCRIPTION
The prepackaged MassPREP™ Oligonucleotide Separation Technology (OST) Standard is designed for verification of HPLC/UPLC instrument and column performance for analysis of synthetic oligonucleotides. Approximately equimolar amounts of 15, 20, 25, 30 and 35 nucleotide (nt) long oligodeoxythymidines are lyophilized and packaged in 1.5 ml LC vials. The shipped vial is vacuum-sealed in foil pouches to reduce degradation that can occur by excessive exposure to light and air. Approximately 1 nmole of each oligonucleotide is present in the vial. It is recommended that this standard be used on a regular basis for benchmarking column and system performance, similar to the QCRM product line.