DESCRIPTION
Octet® SPR HisCap sensor chips consist of pre-immobilized nitrilotriacetic acid (NTA) within a nondextran polysaccharide 3D surface, which can be used for affinity capture coupling. In comparison to the strong interaction between streptavidin and biotin, the lower bond strength observed between NTA and a His-tag allows easy removal of His-tagged ligand proteins and regeneration of sensor chip surfaces using a variety of conditions, including imidazole, SDS and EDTA.
Top Features of the Octet® SPR HisCap Sensor Chip:
High binding capacity
Popular Applications for the Octet® SPR HisCap Sensor Chip:
Kinetics
Affinity
Screening
LMW binding