MultiScreen IP Filter Plate, 0.45 µm, clear, non-sterile
Net Price
189
Availability
4 weeks
PROPERTIES
Automation Compatible
No
Background Information
Increasing drug candidate predictability earlier in the discovery pipeline using non-cell-based assays can improve candidate throughput during the ADME stage. Non-cell-based permeability assays are predictive models for oral absorption of development candidates.MultiScreen Permeability, MultiScreen-IP, and MultiScreen Acceptor plates support artificial membrane strategies for predicting passive transport.Membranes have uniform pore structure and density for reliable transport: - Individual wells minimize candidate cross-talk - Compatibility with automated liquid handling systems increases throughput Permeability Assay: - The MultiScreen Permeability plate has a polycarbonate membrane, which supports a hexane/hexadecane artificial layer for permeability assays.1PAMPA Assay: - The MultiScreen-IP plate has a hydrophobic PVDF membrane, which supports a lipid bilayer for PAMPA asays.2,3MultiScreen Acceptor Plate: - The MultiScreen Acceptor plate can be used with either plate to capture passively transported compounds. Constructed of 100% PTFE, the plate can improve LC/MS results depending on the charge of the small molecules being evaluated.
Catalogue Number
MAIPNTR10
Chemistry
Hydrophobic Polyvinylidene Fluoride (PVDF)
Color Code
Clear
Device Material
Acrylic
Filter Code
IP
Key Applications
PAMPA
Material Size
10
Media
Immobilon®-P
Number of Wells
96
Pore Size
0.45 µm
Sterility
Non-Sterile
Trade Name
MultiScreen
Volume
50 µL–250 µL
DESCRIPTION
This clear 96 well filter plate has a Hydrophobic PVDF membrane used for PAMPA.