LiChrospher® RP-18 endcapped is a reliable and versatile traditionally produced spherical silica gel carrier with revered phase properties. It is well suited for the separation of neutral, acidic and weak basic compounds. This sorbent is packed into a LiChroCART® 25-4 HPLC pre-cartridge, to be used in connection with LiChroCART® HPLC cartridges, packed with LiChrospher® RP-18 endcapped (5µm or 10µm). The connection is being accomplished by use of the LiChroCART® coupling kit (1.50082).