LiChrospher® RP-8 is a reliable and versatile traditionally produced spherical silica gel carrier with C-8 reversed phase properties. It is well suited for the separation of neutral, acidic and weak basic compounds. This sorbent is packed into a LiChroCART® 25-4 HPLC pre-cartridge, to be used in connection with LiChroCART® HPLC cartridges, packed with LiChrospher® Si 60 (5µm or 10µm). The connection is being accomplished by use of the LiChroCART® coupling kit (1.50082).