LiChrospher® CN has polar and hydrophobic properties, thus can be used as less polar alternative to LiChrospher® Si 60 in normal phase applications or as less hydrophobic alternative to LiChrospher® RP-8 in reversed phase applications. This sorbent is packed into a LiChroCART® 250-4 HPLC cartridge for semipreparative separations. The connection to the HPLC system is being accomplished by use of the manu-CART® cartrige holder (1.51486)