CYT17072703 - Cytiva - Resins - Chromatography - Lab supplies

: Catalog No. CYT17072703

Part No. 17072703
Supplier Cytiva

SOURCE 15RPC, 500 mL

Net Price

5793

Availability

4 weeks

PROPERTIES

Pack size

200 mL
Autoclavable

20 min at 121°C
Chemical stability

Stable in commonly used aqueous buffers 1.0 M HCl, 1 M NaOH, 1 M HCl/ 90% methanol, 90% HAc, 0.45 M NaOH/40% 2-propanol, 6 M guanidine hydrochloride, n-propanol, 20% ethanol, acetone
Storage

4 to 30°C, 20% Ethanol or 70% Acetonitrile
Certificate of Analysis

Yes
BioProcess resin

Yes
Ligand

Matrix surface
Matrix

Polystyrene/divinyl benzene
Pressure/Flow Specification

400 cm/h, 1000 kPa, FineLINE 100 column, bed height 10 cm, i.d. 10 cm
pH stability, CIP

1–14
pH stability, operational

1–12
Binding Capacity/ml Chromatography Medium

~10 mg BSA /mL resin at 300 cm/h, ~30 mg bacitracin/mL resin\nat 300 cm/h, ~50 mg insulin/mL resin at 300 cm/h

DESCRIPTION

Source 15RPC is designed for reversed phase chromatography (RPC) with full pH range stability and suitable for polishing steps in industrial processes requiring high flow velocities and low back-pressure Mono-sized 15 µm rigid beads gives low back pressures and high flow rates allowing for high productivity. Designed for high resolution reversed phase chromatography of proteins, peptides and oligonucleotides. High chemical stability allowing for wide range of working conditions with good resistance to cleaning conditions at high pH BioProcess resin supported for industrial applications. SOURCE 15RPC is based on a 15 μm, monosized, rigid polystyrene/divinyl benzene matrix. This gives low back pressures and high flow rates during operation allowing for high productivity. The 15 μm bead size allows for very high resolution chromatography steps. High quality assurance standards in combination with the patented production method, particle structure is consistent both bead-to-bead and batch-to-batch.A controlled pore size distribution and large specific surface area offer excellent capacity for a wide range of molecules, from small peptides and oligonucleotides up to large proteins. With full pH range stability, SOURCE 15RPC is a strong alternative to silica-based RPC matrices.SOURCE 15RPC is available in a range of different bulk pack sizes for easy scale-up and process development. As member of the BioProcess resin range, SOURCE 15RPC meets industrial demands with security of supply and comprehensive technical and regulatory support