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Catalog No. CYT17051004
Part No. 17051004
Supplier Cytiva
Q Sepharose Fast Flow, 5 L
Net Price
Special offer
Availability

4 weeks

PROPERTIES
  • Pack size
    300 mL
  • Chemical stability
    Stable to commonly used aqueous buffers:1.0 M NaOH, 8 M urea, 8 M guanidine hydrochloride, 70% ethanol
  • Storage
    4 to 30°C, 20% Ethanol
  • Certificate of Analysis
    Yes
  • BioProcess resin
    Yes
  • Ion Exchanger Type
    Strong anion exchanger
  • Ionic Capacity
    0.18-0.24 mmol Cl-/ml medium
  • Ligand
    Quaternary amine
  • Matrix
    cross-linked, 6% agarose particles
  • Pressure/Flow Specification
    400-700 cm/h, 100 kPa, XK 50/30 column, bed height 15 cm
  • pH stability, CIP
    2–14
  • pH stability, operational
    2–12
DESCRIPTION
Q Sepharose Fast Flow is a strong anion exchanger based on the well established Sepharose Fast Flow ion exchange platform, extensively used for preparative protein separations in both research and industrial applications. Well-proven strong anion exchanger developed for industrial downstream processes. Used extensively for capture and intermediate purification of a wide range of approved biopharmaceuticals The industry standard for ion exchange chromatography during recent decades High chemical stability allows for well proven CIP and sanitization protocols The hydrophilic nature of the base matrix ensures low levels of non-specific binding leading to low levels of host cell-derived impurities in the elution pool. Q Sepharose Fast Flow is part of the Sepharose Fast Flow ion exchange platform, which has been the industrial standard for ion exchange chromatography during recent decades. It is composed of crosslinked 6% agarose beads, with quaternary ammonium (Q) strong anion exchange groups. Q Sepharose Fast Flow has high chemical stability, allowing well proven cleaning-in-place (CIP) and sanitization protocols. Scale-up with Q Sepharose Fast Flow is straight forward and the resin is available in a range of pre-packed process development tools. As member of the BioProcess resins range, Q Sepharose Fast Flow meets industrial demands with security of supply and comprehensive technical and regulatory support.
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