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Catalog No. CYT17372404
Part No. 17372404
Supplier Cytiva
Capto Core 400, 5L
Net Price
Special offer
Availability

4 weeks

PROPERTIES
  • Pack size
    25 mL
  • Chemical stability
    All commonly used aqueous buffers, 1 M sodium hydroxide (NaOH)§, 6 M guanidine hydrochloride, 30% isopropanol, and 70% ethanol.
  • BioProcess resin
    Yes
  • Ionic Capacity
    40-85 µmol/mL(Cl-)
  • Ligand
    Octylamine
  • Matrix
    Highly cross‑linked agarose
  • pH stability, CIP
    3 to 14
  • pH stability, operational
    3 to 13
  • Avoid Using
    Oxidizing agents, citrate buffers
  • Flow velocity
    700 cm/h
DESCRIPTION
Novel core bead technology and multimodal ligand give Capto Core 400 dual functionality, size exclusion and binding chromatography, in one chromatography resin. Significantly improved productivity enabled by up to 100‑fold higher sample load and significantly higher flow rates compared with SEC. Bead with ligand‑activated core and inactive shell allows efficient capture of impurities, while target molecules are collected in the flowthrough. Straightforward optimization due to flow-through chromatography and robust performance, allowing for a wide window of operation. Capto Core 400 is an excellent alternative to size‑exclusion chromatography (SEC) resins that are typically employed in the final stages of virus purification in vaccine manufacture. Learn about prepacked HiScreen Capto Core 400 and HiTrap Capto Core 400 columns or the Capto Core 700 resin.
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