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Catalog No. CYT17531605
Part No. 17531605
Supplier Cytiva
Capto Q, 10 L
Net Price
Special offer
Availability

4 weeks

PROPERTIES
  • Chromatography technique
    Ion Exchange Chromatography
  • Pack size
    100 mL
  • Chemical stability
    Commonly used aqueous buffers, 1 M acetic acid, 1 M NaOH, 8 M urea, 6 M guanidine hydrochloride, 30% isopropanol and 70% ethanol
  • Storage
    4 to 30°C, 20% Ethanol
  • BioProcess resin
    Yes
  • Ion Exchanger Type
    Strong anion exchanger
  • Ionic Capacity
    0.16-0.22 mmol Cl-/ml medium
  • Ligand
    Quaternary amine
  • Matrix
    Highly cross-linked agarose with dextran surface extender
  • Pressure/Flow Specification
    0.3 MPa at 700 cm/h, 1 m diameter column, 20 cm bed height
  • pH stability, CIP
    2–14
  • pH stability, operational
    2–12
DESCRIPTION
Designed to meet the demands of modern, large-scale manufacturers Capto Q’s shorter processing times can reduce exposure of the target protein. Strong anion exchanger for high-productivity capture and intermediate purification when high volume throughput is essential. High dynamic binding capacity at high flow raises productivity. High-volume throughput cuts process times. Cost-effective processing with smaller unit operations. Resin fulfills industrial demands for security of supply, robust performance, and regulatory support. Offers increased productivityCapto Q is designed for capture and intermediate purification of proteins from large feed volumes. It is composed of a rigid, high-flow agarose matrix modified with dextran surface extenders and a strong quaternary ammonium (Q) anion exchanger. The combination of high volume throughput and high dynamic binding capacity for Capto Q raises the productivity in industrial downstream processes. Durable and stableCapto Q withstands effective and rigorous cleaning-in-place (CIP) procedure and the chemical stability supports long resin lifetime.Prepacked columns and other formatsCapto Q is available in the following formats: Process development scale – prepackedPreDictor Capto Q filter plates – 96-well plates for high-throughput screening or process development.PreDictor Capto Q RoboColumn™ units – miniaturized columns for high-throughput process development.HiScreen Capto Q columns – optimized for method and process development. Lab/research scale – prepacked for manual purificationHiTrap Capto Q columns – for easy use with a syringe, peristaltic pump, or chromatography system.Lab/research scale – prepacked for automated purification and analysisHiTrap Capto Q columns – for easy use with a syringe, peristaltic pump, or chromatography system.Process-scale purification – prepackedReadyToProcess Capto Q columns – 1 L and larger columns for clinical manufacturing that avoid the need for cleaning and cleaning validation.Lab/research scale – prepacked for manual purificationHiTrap Capto Q ImpRes columns – for easy use with a syringe, peristaltic pump, or chromatography system.Lab/research scale – prepacked for automated purification and analysisHiTrap Capto Q ImpRes columns – for easy use with a syringe, peristaltic pump, or chromatography system.Process-scale purification – prepackedReadyToProcess Capto Q ImpRes columns – 1 L and larger columns for clinical manufacturing that avoid the need for cleaning and cleaning validation.
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