Butyl-S Sepharose 6 Fast Flow is the least hydrophobic resin in the Sepharose Fast Flow hydrophobic interaction chromatography (HIC) range and is particularly useful during the initial stages of a purification process to remove the bulk of impurities Binds and elutes relatively strong hydrophobic molecules at comparatively low salt concentrations The least hydrophobic resin in the well proven Sepharose Fast Flow HIC range Purifies recombinant Hepatitis B virus surface antigen from CHO cells Developed and optimized in cooperation with a process-scale manufacturer of biopharmaceuticals The hydrophilic nature of the base matrix ensures low levels of non-specific binding. Butyl-S Sepharose 6 Fast Flow is part of the Sepharose Fast Flow HIC platform, which has been an industrial standard for HIC chromatography during recent decades. Butyl-S Sepharose 6 Fast Flow is composed of cross-linked 6% agarose beads modified with butyl groups via a thio-ether linkage. It will exhibit a different selectivity compared to Butyl Sepharose 4 Fast Flow and other HIC Sepharose Fast Flow products.This resin is designed for the binding and elution of relatively strong hydrophobic molecules at comparatively low salt concentrations. Butyl-S Sepharose 6 Fast Flow is particularly useful during the initial stages of a separation process to remove the bulk of impurities without stringent requirements for conditioning of the sample (e.g. adjustment of pH, salt concentration etc.)Butyl-S Sepharose 6 Fast Flow is available in a range of different bulk pack sizes and convenient pre-packed formats for easy scale-up and process development. As member of the BioProcess resins range, Butyl-S Sepharose 6 Fast Flow meets industrial demands with security of supply and comprehensive technical and regulatory support