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Catalog No. CYT17545802
Part No. 17545802
Supplier Cytiva
KappaSelect, 200 mL
Net Price
6463
Availability

4 weeks

PROPERTIES
  • Chromatography technique
    Antibody affinity chromatography
  • Pack size
    25 mL
  • Order Information
    If you are interested in large-scale quantities, please contact your local Cytiva representative
  • Chemical stability
    Stable to commonly used aqueous buffers: 6 M urea, 6 M guanidine hydrochloride, 70 % ethanol, 30 % isopropanol
  • Application
    KappaSelect is an affinity chromatography resin designed for the purification of Fab (kappa) with high binding capacity, purity and yield
  • Storage
    2 to 8°C, 20% Ethanol
  • BioProcess resin
    Yes
  • Ligand
    Recombinant protein (Mr 13 000), produced in S. cerevisiae, with affinity for the constant domain of the immunoglobulin kappa light chain
  • Matrix
    Highly cross-linked agarose
  • Pressure/Flow Specification
    300 kPa at 600 cm/h, 1 m diameter column, 20 cm bed height
  • pH stability, CIP
    2–12
  • pH stability, operational
    3–10
  • Binding Capacity/ml Chromatography Medium
    Approximately 15 mg Fab/mL of resin
  • Ligand Coupling Method
    Amide linkage
DESCRIPTION
Antibody fragments, especially Fabs, are getting increased attention as potential biopharmaceuticals because they have some advantages over monoclonal antibodies (MAbs), KappaSelect is an affinity resin designed for the purification of human Fab (kappa) fragments
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