Pegasus™ Protect membrane in Kleenpak™ capsules, a Pall Life Sciences product, enables process developers to quickly deliver a robust, scalable virus filtration process using a minimum of sample volume, and be confident of successful virus validation. Pegasus Protect virus prefiltration combines with Pegasus Prime virus filtration to deliver the first gamma-sterilized pre-filter & virus filter combination. Together, these simplify process development, validation and operations while saving time and delivering improved process economy. Process developers can quickly deliver a robust, scalable virus filtration process using a minimum of sample volume, and be confident of successful virus validation. This choice supports clinical manufacturing with a solution that is easy to use and versatile to work alone or with integrated and automated single-use systems. Materials of Construction Filter Membrane: Nylon Support and Drainage: Polyester Core and cage: Polypropylene Capsule hardware: Polyester Retention Ratings Pore size : 0.2 μm nominal Effective Filter Area (EFA) (Nominal) 286 cm2 Operating Parameters Maximum Temperature: 40°C Maximum Pressure: 4.1 bar (60 psi)* Maximum Differential Pressure: 4.1 bar (60 psi)* Recommended Operating Conditions 35 mbard (0.5 psid) or 2 mL/min water at 20°C* *when used with Pegasus Prime Mini Kleenpak capsules at 2.1 bard (30 psid) Steam Autoclaving Cumulative autoclave time: 16 hours at 125°C* 4 hours at 140°C * laboratory tests (1-hour cycles). Contact Pall for recommended procedures Warning; Kleenpak capsules must not be steam sterilized in-situ by passing steam through under pressure Typical Hold-Up Volume (with air purge) Dimensions (Nominal) Length: 11.7 cm (4.6 in.) Diameter including valves: 9.4 cm (3.7 in.) Connection Type 1 in. sanitary flange inlet ½ in. sanitary flange outlet Scalable Solutions Prefiltration area and flowrate are critical variables that may affect the performance of Pegasus Protect prefiltration and Pegasus Prime virus removal filters when used in combination. To control these variables Pegasus Protect prefiltration media is available in a range of formats, designed to maintain a consistent pre-filter to virus-filter ratio. This control ensures predictable and consistent performance at all scales from the initial Microdisc scale trials to clinical manufacturing.