AcroPak™ 500, 1000, & 1500 capsules with Supor™ membrane, a Pall Life Sciences product, are designed for cost-effective filtration of buffers, tissue culture media, and other biological solutions Newer technology recommended for simplified scale-up Disposable design reduces labor costs associated with assembling, cleaning, and testing stainless steel filter holders Encapsulated format for ease of use Extended life with built-in MachV asymmetric prefilter layer for maximum flow and throughput performance Low adsorption and high chemical compatibility with hydrophilic polyethersulfone membrane for high compatibility over the entire pH range and low protein binding Gamma-irradiated, non-pyrogenic, and non-cytotoxic Inherently hydrophilic for reliable integrity testing Materials of Construction Filter Media: Supor EKV [hydrophilic polyethersulfone (PES)] membrane Housing, Vent Plug, and Support Material: Polypropylene Filling Bell: Polycarbonate (no filling bell on sanitary flange option) Sealing Technology: Thermal bonding without adhesives Pore Size 0.2 μmEffective Filtration Area 400 Series: 375 cm2 800 Series: 750 cm2 1500 Series: 1500 cm2 Dimensions Housing Diameter (including valves): 9.4 cm (3.7 in.) 400 Series Housing Length: 12460: 11.7 cm (4.6 in.) 12461: 15.7 cm (6.2 in.) 800 Series Housing Length: 12463: 15.7 cm (6.2 in.) 12464: 19.7 cm (7.7 in.) 1500 Series Housing Length: 12466: 17.4 cm (6.8 in.) 12467: 21.0 cm (8.3 in.) Inlet/Outlet Connections 400 Series 12460: 25 - 38 mm (1 - 1.5 in.) sanitary flange inlet/outlet connection 12461: 13 mm (1/2 in.) hose barb inlet/outlet connection 800 Series 12463: 25 - 38 mm (1 - 1.5 in.) sanitary flange inlet/outlet connection 12464: 13 mm (1/2 in.) hose barb inlet/outlet connection 1500 Series 12466: 25 - 38 mm (1 - 1.5 in.) sanitary flange inlet/outlet connection 12467: 13 mm (1/2 in.) hose barb inlet/outlet connection Maximum Operating Temperature 40°C (104°F) at 4.0 bar (400 kPa, 58 psi) Maximum Operating Pressure 5.2 bar (520 kPa, 75 psi) at 20°C (68°F) Recommended Integrity Test Minimum Bubble Point - Water 3.32 bar (332 kPa, 48 psi) Typical Water Flow Rate Typical Water Flow Rate 400 Series: 700 mL/min/0.1 bar (483 mL/min/psi) 800 Series: 1.5 L/min/0.1 bar (1.0 L/min/psi) 1500 Series: 3.2 L/min/0.1 bar (2.2 L/min/psi) Bacterial Retention Lot samples retain a minimum of 107 cfu/cm2 of B. diminuta per modified ASTM F838, current revision Endotoxin Level Biological Safety Passes United States Pharmacopeia (USP) Biological Reactivity Test, In Vivo Sterilization Sterilized by gamma irradiation and individually packaged Applications Suitable for sterile filtration of a wide range of fluids, including: Buffers Biological fluids Cell culture media Ophthalmic products