AcroPak™ 20 Filters with Supor™ membrane, a Pall Life Sciences product, deliver efficient processing of liquid volumes up to 2 L. Supor membrane has high flow rates and throughputs, and is ideal for solutions where low protein binding is required. Not recommended for use with some ketones. Efficiently processes up to 2 L of chemical and biological fluids. Sterilization by gamma irradiation eliminates potential contamination by EtO residuals. Upstream vent prevents vapor lock. Built-in prefilter extends filter life when particulate-laden solutions such as serum-containing media are processed. Materials of Construction Filter Media: Supor [hydrophilic polyethersulfone (PES)] membrane Housing, Vent Plug: Polypropylene Sealing Technology: Thermal bonding Filling Bell: Polycarbonate Pore Size 0.8/0.2 μm Effective Filtration Area 20 cm2 Dimensions Housing Length: 8.3 cm (3.3 in.) Housing Diameter: 6.7 cm (2.7 in.) Inlet/Outlet Connections 6.4 - 12.7 mm (1/4 - 1/2 in.) diameter stepped hose barb with female luer slip interior and filling bell outlet Typical Hold-Up Volume (with 10 psi air purge)≤ 2.5 mL Maximum Operating Temperature and Pressure 60°C (140°F) at 1.0 bar (100 kPa, 15 psi) 4.1 bar (410 kPa, 60 psi) at 21 - 24°C (70 - 75°F) Recommended Integrity Test Minimum Bubble Point - Water 3.5 bar (350 kPa, 51 psi) Typical Water Flow Rate mL/min at 0.1 bar (10 kPa): 40 mL/min/psi: 28 Bacterial Retention Lot samples retain a minimum of 107 cfu/cm2 of B. diminuta per modified ASTM F838, current revision Endotoxin Level Biological Safety Passes United States Pharmacopeia (USP) Biological Reactivity Test, In Vivo Sterilization Can withstand one autoclave cycle at 125°C (257°F) for 60 minutes; water wet capsule prior to autoclaving PN 12203 is sterilized by gamma irradiation and individually packaged Applications Designed to add convenience to small- and medium-volume filtration (sterile and non-sterile) Suitable for use with fluids containing dilute proteins, preservatives, or other critical components Sterile filtration of media and buffers