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Agilent offers the largest, most modern liquid chromatography (LC) column portfolios for small molecule analysis, with columns suitable for nearly all separation modes and applications.


Whether you are performing conventional or ultra-fast chromatography, separating biomolecules, or analyzing complex compounds, the industry’s highest-performing compounds deliver fast, reproducible results – all engineered with unparalleled quality and reliability.

Catalog No. Product Net Price
AGIL440910-901 Agilent Prep-Sil Scalar column, 100Å, 4.6 x 250 mm, 10 µm, 400 bar pressure limit 519 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 250 mm
  • Phase
  • Prep-Sil
  • UNSPSC Code
  • 41115711
  • Brand
  • Agilent Prep
  • Carbon Load
  • 0 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • Preparative HPLC
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 10 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-10
  • Pore Size
  • 100 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Normal Phase
  • Shipping Solvent
  • Hexane
AGIL443905-901 Agilent Prep-Sil Scalar column, 100Å, 4.6 x 150 mm, 5 µm, 400 bar pressure limit 469 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 150 mm
  • Phase
  • Prep-Sil
  • UNSPSC Code
  • 41115711
  • Brand
  • Agilent Prep
  • Carbon Load
  • 0 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • Preparative HPLC
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-10
  • Pore Size
  • 100 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Normal Phase
  • Shipping Solvent
  • Hexane
AGIL443910-901 Agilent Prep-Sil Scalar column, 100Å, 4.6 x 150 mm, 10 µm, 400 bar pressure limit 469 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 150 mm
  • Phase
  • Prep-Sil
  • UNSPSC Code
  • 41115711
  • Brand
  • Agilent Prep
  • Carbon Load
  • 0 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • Preparative HPLC
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 10 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-10
  • Pore Size
  • 100 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Normal Phase
  • Shipping Solvent
  • Hexane
AGIL446905-501 Agilent Prep-Sil, 50 x 50 mm, 5 µm 5915 
Add to Cart
  • Inner Diameter (ID)
  • 50 mm
  • Length
  • 50 mm
  • Phase
  • Prep-Sil
  • UNSPSC Code
  • 41115711
  • Brand
  • Agilent Prep
  • Carbon Load
  • 0 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • Preparative HPLC
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-8
  • Pore Size
  • 100 Å
  • Pressure Rating
  • 340 bar
  • Separation Mode
  • Normal Phase
AGIL446905-901 Agilent Prep-Sil Scalar column, 100Å, 4.6 x 50 mm, 5 µm, 400 bar pressure limit 393 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 50 mm
  • Phase
  • Prep-Sil
  • UNSPSC Code
  • 41115711
  • Brand
  • Agilent Prep
  • Carbon Load
  • 0 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • Preparative HPLC
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-10
  • Pore Size
  • 100 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Normal Phase
  • Shipping Solvent
  • Hexane
AGIL449905-501 Agilent Prep-Sil, 50 x 100 mm, 5 µm 6052 
Add to Cart
  • Inner Diameter (ID)
  • 50 mm
  • Length
  • 100 mm
  • Phase
  • Prep-Sil
  • UNSPSC Code
  • 41115711
  • Brand
  • Agilent Prep
  • Carbon Load
  • 0 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • Preparative HPLC
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-8
  • Pore Size
  • 100 Å
  • Pressure Rating
  • 200 bar
  • Separation Mode
  • Normal Phase
AGIL449905-901 Agilent Prep-Sil Scalar column, 100Å, 4.6 x 100 mm, 5 µm, 400 bar pressure limit 448 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 100 mm
  • Phase
  • Prep-Sil
  • UNSPSC Code
  • 41115711
  • Brand
  • Agilent Prep
  • Carbon Load
  • 0 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • Preparative HPLC
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-10
  • Pore Size
  • 100 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Normal Phase
  • Shipping Solvent
  • Hexane
NMA080505 NOVEMA Max, 8 x 50 mm, 5 µm. GPC/SEC guard column, ships in water 591 
Add to Cart
  • Inner Diameter (ID)
  • 8 mm
  • Length
  • 50 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • NOVEMA Max
  • Guard Column
  • Yes
  • Maximum Temperature
  • 80 °C
  • Particle Size
  • 5 µm
  • pH Range
  • 2-12
  • Pressure Rating
  • 150 bar
  • Shipping Solvent
  • Water
NMA0830051E3 NOVEMA Max, 1000Å, 8 x 300 mm, 5 µm. GPC/SEC column, molecular weight range 1000 to 10^6, ships in water 2270 
Add to Cart
  • Inner Diameter (ID)
  • 8 mm
  • Length
  • 300 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • NOVEMA Max
  • Guard Column
  • No
  • Maximum Temperature
  • 80 °C
  • Molecular Weight Lower Limit
  • 1000 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Individual Pore Size
  • pH Range
  • 2-12
  • Pore Size
  • 1000 µm
  • Pressure Rating
  • 150 bar
  • Shipping Solvent
  • Water
NMA0830053E1 NOVEMA Max, 30Å, 8 x 300 mm, 5 µm. GPC/SEC column, molecular weight range 100 to 3x10^4, ships in water 2270 
Add to Cart
  • Inner Diameter (ID)
  • 8 mm
  • Length
  • 300 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • NOVEMA Max
  • Guard Column
  • No
  • Maximum Temperature
  • 80 °C
  • Molecular Weight Lower Limit
  • 100 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Individual Pore Size
  • pH Range
  • 2-12
  • Pore Size
  • 30 µm
  • Pressure Rating
  • 150 bar
  • Shipping Solvent
  • Water

Overview

The small molecule column portfolio includes state-of-the-art superficially porous InfinityLab Poroshell 120 columns as well as traditional fully porous ZORBAX, Polaris, and Pursuit columns.

When you choose Agilent small molecule LC columns, you get more than just a dependable product. You also get unmatched technical support from the world’s largest chromatography supplier.


Agilent gel permeation chromatography (GPC) and size exclusion chromatography (SEC) columns and standards have been the top-selling in the polymer industry for over 40 years. GPC and SEC is used to determine the molecular weight and size distribution of macromolecules. SEC and GPC columns generate accurate, reliable data for critical polymer parameters, including dispersity (PDI), molecular weight mass average (Mw), number average (Mn), and z-average (Mz).


The importance of understanding the attributes of a biologic drug, and the processes used to create it, cannot be underestimated.  Agilent AdvanceBio LC columns are designed and produced to provide results you can be sure of when analyzing highly complex biotherapeutic molecules and monitoring their purity, potency, and other critical quality attributes.



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