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Agilent offers the largest, most modern liquid chromatography (LC) column portfolios for small molecule analysis, with columns suitable for nearly all separation modes and applications.


Whether you are performing conventional or ultra-fast chromatography, separating biomolecules, or analyzing complex compounds, the industry’s highest-performing compounds deliver fast, reproducible results – all engineered with unparalleled quality and reliability.

Catalog No. Product Net Price
AMA0830101E2LS GRAM Lux, 100Å, 8 x 300 mm, 10 µm. GPC/SEC column, molecular weight range 100 to 6x10^4, ships in DMAc, pre-equilibrated for use with light scattering detectors 2108 
Add to Cart
  • Inner Diameter (ID)
  • 8 mm
  • Length
  • 300 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • GRAM
  • Guard Column
  • No
  • Maximum Temperature
  • 90 °C
  • Molecular Weight Lower Limit
  • 100 Da
  • Particle Size
  • 10 µm
  • Particle Type
  • Individual Pore Size
  • Pore Size
  • 100 µm
  • Pressure Rating
  • 100 bar
  • Shipping Solvent
  • DMAc
AMA0830101E3LS GRAM Lux, 1000Å, 8 x 300 mm, 10 µm. GPC/SEC column, molecular weight range 1000 to 10^6, ships in DMAc, pre-equilibrated for use with light scattering detectors 2108 
Add to Cart
  • Inner Diameter (ID)
  • 8 mm
  • Length
  • 300 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • GRAM
  • Guard Column
  • No
  • Maximum Temperature
  • 90 °C
  • Molecular Weight Lower Limit
  • 1000 Da
  • Particle Size
  • 10 µm
  • Particle Type
  • Individual Pore Size
  • Pore Size
  • 1000 µm
  • Pressure Rating
  • 100 bar
  • Shipping Solvent
  • DMAc
AMA0830101E4 GRAM, 10^4Å, 8 x 300 mm, 10 µm. GPC/SEC column, molecular weight range 10^4 to 5x10^7, ships in DMAc 1874 
Add to Cart
  • Inner Diameter (ID)
  • 8 mm
  • Length
  • 300 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • GRAM
  • Guard Column
  • No
  • Maximum Temperature
  • 90 °C
  • Molecular Weight Lower Limit
  • 10000 Da
  • Particle Size
  • 10 µm
  • Particle Type
  • Individual Pore Size
  • Pore Size
  • 10000 µm
  • Pressure Rating
  • 100 bar
  • Shipping Solvent
  • DMAc
AMA0830103E3LS GRAM Lux, 3000Å, 8 x 300 mm, 10 µm. GPC/SEC column, molecular weight range 5000 to 5x10^6, ships in DMAc, pre-equilibrated for use with light scattering detectors 2108 
Add to Cart
  • Inner Diameter (ID)
  • 8 mm
  • Length
  • 300 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • GRAM
  • Guard Column
  • No
  • Maximum Temperature
  • 90 °C
  • Molecular Weight Lower Limit
  • 5000 Da
  • Particle Size
  • 10 µm
  • Particle Type
  • Individual Pore Size
  • Pore Size
  • 3000 µm
  • Pressure Rating
  • 100 bar
  • Shipping Solvent
  • DMAc
MCA080505 MCX, 8 x 50 mm, 5 µm. GPC/SEC guard column, ships in water 591 
Add to Cart
  • Inner Diameter (ID)
  • 8 mm
  • Length
  • 50 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • MCX
  • Guard Column
  • Yes
  • Maximum Temperature
  • 80 °C
  • Particle Size
  • 5 µm
  • pH Range
  • 1-13
  • Pressure Rating
  • 120 bar
  • Shipping Solvent
  • Water
MCA080510 MCX, 8 x 50 mm, 10 µm. GPC/SEC guard column, ships in water 591 
Add to Cart
  • Inner Diameter (ID)
  • 8 mm
  • Length
  • 50 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • MCX
  • Guard Column
  • Yes
  • Maximum Temperature
  • 80 °C
  • Particle Size
  • 10 µm
  • pH Range
  • 1-13
  • Pressure Rating
  • 80 bar
  • Shipping Solvent
  • Water
MCA0830051E2 MCX, 100Å, 8 x 300 mm, 5 µm. GPC/SEC column, molecular weight range 100 to 10^4, ships in water 2202 
Add to Cart
  • Inner Diameter (ID)
  • 8 mm
  • Length
  • 300 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • MCX
  • Guard Column
  • No
  • Maximum Temperature
  • 80 °C
  • Molecular Weight Lower Limit
  • 100 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Individual Pore Size
  • pH Range
  • 1-13
  • Pore Size
  • 100 µm
  • Pressure Rating
  • 120 bar
  • Shipping Solvent
  • Water
MCA0830051E3 MCX, 1000Å, 8 x 300 mm, 5 µm. GPC/SEC column, molecular weight range 100 to 7x10^4, ships in water 2202 
Add to Cart
  • Inner Diameter (ID)
  • 8 mm
  • Length
  • 300 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • MCX
  • Guard Column
  • No
  • Maximum Temperature
  • 80 °C
  • Molecular Weight Lower Limit
  • 100 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Individual Pore Size
  • pH Range
  • 1-13
  • Pore Size
  • 1000 µm
  • Pressure Rating
  • 120 bar
  • Shipping Solvent
  • Water
MCA0830051E5 MCX, 10^5Å, 8 x 300 mm, 5 µm. GPC/SEC column, molecular weight range 1000 to 10^6, ships in water 2202 
Add to Cart
  • Inner Diameter (ID)
  • 8 mm
  • Length
  • 300 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • MCX
  • Guard Column
  • No
  • Maximum Temperature
  • 80 °C
  • Molecular Weight Lower Limit
  • 1000 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Individual Pore Size
  • pH Range
  • 1-13
  • Pore Size
  • 100000 µm
  • Pressure Rating
  • 120 bar
  • Shipping Solvent
  • Water
MCA0830055E2 MCX, 500Å, 8 x 300 mm, 5 µm. GPC/SEC column, molecular weight range 100 to 3.5x10^4, ships in water 2202 
Add to Cart
  • Inner Diameter (ID)
  • 8 mm
  • Length
  • 300 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • MCX
  • Guard Column
  • No
  • Maximum Temperature
  • 80 °C
  • Molecular Weight Lower Limit
  • 100 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Individual Pore Size
  • pH Range
  • 1-13
  • Pore Size
  • 500 µm
  • Pressure Rating
  • 120 bar
  • Shipping Solvent
  • Water

Overview

The small molecule column portfolio includes state-of-the-art superficially porous InfinityLab Poroshell 120 columns as well as traditional fully porous ZORBAX, Polaris, and Pursuit columns.

When you choose Agilent small molecule LC columns, you get more than just a dependable product. You also get unmatched technical support from the world’s largest chromatography supplier.


Agilent gel permeation chromatography (GPC) and size exclusion chromatography (SEC) columns and standards have been the top-selling in the polymer industry for over 40 years. GPC and SEC is used to determine the molecular weight and size distribution of macromolecules. SEC and GPC columns generate accurate, reliable data for critical polymer parameters, including dispersity (PDI), molecular weight mass average (Mw), number average (Mn), and z-average (Mz).


The importance of understanding the attributes of a biologic drug, and the processes used to create it, cannot be underestimated.  Agilent AdvanceBio LC columns are designed and produced to provide results you can be sure of when analyzing highly complex biotherapeutic molecules and monitoring their purity, potency, and other critical quality attributes.



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